The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart
Abstract Background The prevalence of small for gestational age (SGA) may vary depending on the chosen weight-for-gestational-age reference chart. An individual participant data meta-analysis was conducted to assess the implications of using a local reference (STOPPAM) instead of a universal referen...
Published in: | Malaria Journal |
---|---|
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2022
|
Subjects: | |
Online Access: | https://doi.org/10.1186/s12936-022-04307-2 https://doaj.org/article/4dedc147282f44089be3e048f6378425 |
id |
ftdoajarticles:oai:doaj.org/article:4dedc147282f44089be3e048f6378425 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:4dedc147282f44089be3e048f6378425 2023-05-15T15:13:36+02:00 The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart George Mtove Daniel T. R. Minja Omari Abdul Samwel Gesase Kenneth Maleta Titus H. Divala Noel Patson Ulla Ashorn Miriam K. Laufer Mwayiwawo Madanitsa Per Ashorn Don Mathanga Jobiba Chinkhumba Julie R. Gutman Feiko O. ter Kuile Sofie Lykke Møller Ib C. Bygbjerg Michael Alifrangis Thor Theander John P. A. Lusingu Christentze Schmiegelow 2022-10-01T00:00:00Z https://doi.org/10.1186/s12936-022-04307-2 https://doaj.org/article/4dedc147282f44089be3e048f6378425 EN eng BMC https://doi.org/10.1186/s12936-022-04307-2 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04307-2 1475-2875 https://doaj.org/article/4dedc147282f44089be3e048f6378425 Malaria Journal, Vol 21, Iss 1, Pp 1-15 (2022) Malaria in pregnancy Birthweight Reference chart Individual participant data meta-analysis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2022 ftdoajarticles https://doi.org/10.1186/s12936-022-04307-2 2022-12-30T19:49:28Z Abstract Background The prevalence of small for gestational age (SGA) may vary depending on the chosen weight-for-gestational-age reference chart. An individual participant data meta-analysis was conducted to assess the implications of using a local reference (STOPPAM) instead of a universal reference (Intergrowth-21) on the association between malaria in pregnancy and SGA. Methods Individual participant data of 6,236 newborns were pooled from seven conveniently identified studies conducted in Tanzania and Malawi from 2003–2018 with data on malaria in pregnancy, birthweight, and ultrasound estimated gestational age. Mixed-effects regression models were used to compare the association between malaria in pregnancy and SGA when using the STOPPAM and the Intergrowth-21 references, respectively. Results The 10th percentile for birthweights-for-gestational age was lower for STOPPAM than for Intergrowth-21, leading to a prevalence of SGASTOPPAM of 14.2% and SGAIG21 of 18.0%, p < 0.001. The association between malaria in pregnancy and SGA was stronger for STOPPAM (adjusted odds ratio (aOR) 1.30 [1.09–1.56], p < 0.01) than for Intergrowth-21 (aOR 1.19 [1.00–1.40], p = 0.04), particularly among paucigravidae (SGASTOPPAM aOR 1.36 [1.09–1.71], p < 0.01 vs SGAIG21 aOR 1.21 [0.97–1.50], p = 0.08). Conclusions The prevalence of SGA may be overestimated and the impact of malaria in pregnancy underestimated when using Intergrowth-21. Comparing local reference charts to global references when assessing and interpreting the impact of malaria in pregnancy may be appropriate. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 21 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Malaria in pregnancy Birthweight Reference chart Individual participant data meta-analysis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Malaria in pregnancy Birthweight Reference chart Individual participant data meta-analysis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 George Mtove Daniel T. R. Minja Omari Abdul Samwel Gesase Kenneth Maleta Titus H. Divala Noel Patson Ulla Ashorn Miriam K. Laufer Mwayiwawo Madanitsa Per Ashorn Don Mathanga Jobiba Chinkhumba Julie R. Gutman Feiko O. ter Kuile Sofie Lykke Møller Ib C. Bygbjerg Michael Alifrangis Thor Theander John P. A. Lusingu Christentze Schmiegelow The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart |
topic_facet |
Malaria in pregnancy Birthweight Reference chart Individual participant data meta-analysis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background The prevalence of small for gestational age (SGA) may vary depending on the chosen weight-for-gestational-age reference chart. An individual participant data meta-analysis was conducted to assess the implications of using a local reference (STOPPAM) instead of a universal reference (Intergrowth-21) on the association between malaria in pregnancy and SGA. Methods Individual participant data of 6,236 newborns were pooled from seven conveniently identified studies conducted in Tanzania and Malawi from 2003–2018 with data on malaria in pregnancy, birthweight, and ultrasound estimated gestational age. Mixed-effects regression models were used to compare the association between malaria in pregnancy and SGA when using the STOPPAM and the Intergrowth-21 references, respectively. Results The 10th percentile for birthweights-for-gestational age was lower for STOPPAM than for Intergrowth-21, leading to a prevalence of SGASTOPPAM of 14.2% and SGAIG21 of 18.0%, p < 0.001. The association between malaria in pregnancy and SGA was stronger for STOPPAM (adjusted odds ratio (aOR) 1.30 [1.09–1.56], p < 0.01) than for Intergrowth-21 (aOR 1.19 [1.00–1.40], p = 0.04), particularly among paucigravidae (SGASTOPPAM aOR 1.36 [1.09–1.71], p < 0.01 vs SGAIG21 aOR 1.21 [0.97–1.50], p = 0.08). Conclusions The prevalence of SGA may be overestimated and the impact of malaria in pregnancy underestimated when using Intergrowth-21. Comparing local reference charts to global references when assessing and interpreting the impact of malaria in pregnancy may be appropriate. |
format |
Article in Journal/Newspaper |
author |
George Mtove Daniel T. R. Minja Omari Abdul Samwel Gesase Kenneth Maleta Titus H. Divala Noel Patson Ulla Ashorn Miriam K. Laufer Mwayiwawo Madanitsa Per Ashorn Don Mathanga Jobiba Chinkhumba Julie R. Gutman Feiko O. ter Kuile Sofie Lykke Møller Ib C. Bygbjerg Michael Alifrangis Thor Theander John P. A. Lusingu Christentze Schmiegelow |
author_facet |
George Mtove Daniel T. R. Minja Omari Abdul Samwel Gesase Kenneth Maleta Titus H. Divala Noel Patson Ulla Ashorn Miriam K. Laufer Mwayiwawo Madanitsa Per Ashorn Don Mathanga Jobiba Chinkhumba Julie R. Gutman Feiko O. ter Kuile Sofie Lykke Møller Ib C. Bygbjerg Michael Alifrangis Thor Theander John P. A. Lusingu Christentze Schmiegelow |
author_sort |
George Mtove |
title |
The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart |
title_short |
The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart |
title_full |
The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart |
title_fullStr |
The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart |
title_full_unstemmed |
The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart |
title_sort |
choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the intergrowth-21 with a tanzanian birthweight chart |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s12936-022-04307-2 https://doaj.org/article/4dedc147282f44089be3e048f6378425 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 21, Iss 1, Pp 1-15 (2022) |
op_relation |
https://doi.org/10.1186/s12936-022-04307-2 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04307-2 1475-2875 https://doaj.org/article/4dedc147282f44089be3e048f6378425 |
op_doi |
https://doi.org/10.1186/s12936-022-04307-2 |
container_title |
Malaria Journal |
container_volume |
21 |
container_issue |
1 |
_version_ |
1766344139404738560 |