Lack of correlation between rabies virus replication in the brain and antibody isotype profile in genetically modified mice

• Published in: Journal of Venomous Animals and Toxins including Tropical Diseases
• Main Authors: C. A. Consales, C. A. Pereira, E. C. Passos, M. L. Carrieri, N. M. F. Galina, O. A. Sant'Anna
• Format: Article in Journal/Newspaper
• Language: English
• Published: SciELO 2006
• Subjects: rabies; infection; isotypes; nervous system; Arctic medicine. Tropical medicine; RC955-962; Toxicology. Poisons; RA1190-1270; Zoology; QL1-991; Arctic; Pasteur
• Online Access: https://doi.org/10.1590/S1678-91992006000300007; https://doaj.org/article/4da5322c3f8342c7a3897aa0d0dd0a91

The relationship among the phenotypes resistance to infection, virus replication in the brain and isotype production was investigated in genetically modified High (H) or Low (L) antibody responder mouse lines. Although they express the same innate susceptibility to rabies infection, these lines diff...