Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909
The life cycle of Lagochilascaris minor was studied using material collected from human lesion and applying the experimental model: rodents (mice, hamsters), and carnivorae (cats, dogs). In mice given infective eggs, orally, hatch of the third stage larvae was noted in the gut wall, with migration t...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Universidade de São Paulo (USP)
1992
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Online Access: | https://doi.org/10.1590/S0036-46651992000400003 https://doaj.org/article/4d9b91dd681b4d91b6f46845385b348b |
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ftdoajarticles:oai:doaj.org/article:4d9b91dd681b4d91b6f46845385b348b 2024-09-09T19:28:26+00:00 Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909 Dulcinéa Maria Barbosa Campos Lindomar G. Freire Filha Miguel Alípio Vieira Julieta Machado Paçô Moacir A. Maia 1992-08-01T00:00:00Z https://doi.org/10.1590/S0036-46651992000400003 https://doaj.org/article/4d9b91dd681b4d91b6f46845385b348b EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651992000400003 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651992000400003 0036-4665 1678-9946 https://doaj.org/article/4d9b91dd681b4d91b6f46845385b348b Revista do Instituto de Medicina Tropical de São Paulo, Vol 34, Iss 4, Pp 277-287 (1992) Lagochilascaris minor Experimental life cycle Transmission mechanisms Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1992 ftdoajarticles https://doi.org/10.1590/S0036-46651992000400003 2024-08-05T17:49:31Z The life cycle of Lagochilascaris minor was studied using material collected from human lesion and applying the experimental model: rodents (mice, hamsters), and carnivorae (cats, dogs). In mice given infective eggs, orally, hatch of the third stage larvae was noted in the gut wall, with migration to liver, lungs, skeletal musculature and subcutaneous tissue becoming, soon after, encysted. In cats infected with skinned carcasses of mice (60 to 235 days of infection) it was observed: hatch of third stage larvae from the nodules (cysts) in the stomach, migration through the oesophagus, pharynx, trachea, related tissues (rhino-oropharynx), and cervical lymphonodes developing to the mature stage in any of these sites on days 9-20 post inoculation (P.I.). There was no parasite development up to the mature stage in cats inoculated orally with infective eggs, which indicates that the life cycle of this parasite includes an obligatory intermediate host. In one of the cats (fed carcass of infected mice) necropsied on day 43 P.I., it was observed the occurence of the self-infective cycle of L. minor in the lung tissues and in the cervical region which was characterized by the finding of eggs in different stages of development, third stage larvae and mature worms. It's believed that some component of the carnivorae gastrointestinal tracts may preclude the development of third stage larvae from L. minor eggs what explains the interruption of the life cycle in animals fed infective eggs. It's also pointed out the role of the intermediate host in the first stages of the life cycle of this helminth. A partir de material colhido de lesões humanas estudou-se o ciclo evolutivo de Lagochilascaris minor empregando-se o modelo experimental: roedores (camundongos, hamster) e carnívoros (gatos, cão). Em camundongos inoculados com ovos infectantes, por via oral, observou-se eclosão de larvas de 3º estágio na parede do intestino, migração das mesmas para o fígado, pulmão, musculatura esquelética e tecido subcutâneo tornando-se em ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 34 4 277 287 |
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Lagochilascaris minor Experimental life cycle Transmission mechanisms Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Lagochilascaris minor Experimental life cycle Transmission mechanisms Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Dulcinéa Maria Barbosa Campos Lindomar G. Freire Filha Miguel Alípio Vieira Julieta Machado Paçô Moacir A. Maia Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909 |
topic_facet |
Lagochilascaris minor Experimental life cycle Transmission mechanisms Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
The life cycle of Lagochilascaris minor was studied using material collected from human lesion and applying the experimental model: rodents (mice, hamsters), and carnivorae (cats, dogs). In mice given infective eggs, orally, hatch of the third stage larvae was noted in the gut wall, with migration to liver, lungs, skeletal musculature and subcutaneous tissue becoming, soon after, encysted. In cats infected with skinned carcasses of mice (60 to 235 days of infection) it was observed: hatch of third stage larvae from the nodules (cysts) in the stomach, migration through the oesophagus, pharynx, trachea, related tissues (rhino-oropharynx), and cervical lymphonodes developing to the mature stage in any of these sites on days 9-20 post inoculation (P.I.). There was no parasite development up to the mature stage in cats inoculated orally with infective eggs, which indicates that the life cycle of this parasite includes an obligatory intermediate host. In one of the cats (fed carcass of infected mice) necropsied on day 43 P.I., it was observed the occurence of the self-infective cycle of L. minor in the lung tissues and in the cervical region which was characterized by the finding of eggs in different stages of development, third stage larvae and mature worms. It's believed that some component of the carnivorae gastrointestinal tracts may preclude the development of third stage larvae from L. minor eggs what explains the interruption of the life cycle in animals fed infective eggs. It's also pointed out the role of the intermediate host in the first stages of the life cycle of this helminth. A partir de material colhido de lesões humanas estudou-se o ciclo evolutivo de Lagochilascaris minor empregando-se o modelo experimental: roedores (camundongos, hamster) e carnívoros (gatos, cão). Em camundongos inoculados com ovos infectantes, por via oral, observou-se eclosão de larvas de 3º estágio na parede do intestino, migração das mesmas para o fígado, pulmão, musculatura esquelética e tecido subcutâneo tornando-se em ... |
format |
Article in Journal/Newspaper |
author |
Dulcinéa Maria Barbosa Campos Lindomar G. Freire Filha Miguel Alípio Vieira Julieta Machado Paçô Moacir A. Maia |
author_facet |
Dulcinéa Maria Barbosa Campos Lindomar G. Freire Filha Miguel Alípio Vieira Julieta Machado Paçô Moacir A. Maia |
author_sort |
Dulcinéa Maria Barbosa Campos |
title |
Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909 |
title_short |
Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909 |
title_full |
Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909 |
title_fullStr |
Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909 |
title_full_unstemmed |
Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909 |
title_sort |
experimental life cycle of lagochilascaris minor leiper, 1909 ciclo evolutivo experimental de lagochilascaris minor, leiper 1909 |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1992 |
url |
https://doi.org/10.1590/S0036-46651992000400003 https://doaj.org/article/4d9b91dd681b4d91b6f46845385b348b |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 34, Iss 4, Pp 277-287 (1992) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651992000400003 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651992000400003 0036-4665 1678-9946 https://doaj.org/article/4d9b91dd681b4d91b6f46845385b348b |
op_doi |
https://doi.org/10.1590/S0036-46651992000400003 |
container_title |
Revista do Instituto de Medicina Tropical de São Paulo |
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34 |
container_issue |
4 |
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287 |
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