A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial
Objectives: The aim of the study was twofold; 1) to develop a clinical pharmacist-led 12 month lasting follow-up program for patients with established coronary heart disease (CHD) discharged from the University Hospital of North Norway, and 2) to explore the impact of the program with regards to adh...
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Centro de Investigaciones y Publicaciones Farmaceuticas
2015
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ftdoajarticles:oai:doaj.org/article:4c5ee8e1fc3e493cb6990ba424fa3dbe 2023-05-15T17:39:21+02:00 A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial Garcia BH Giverhaug T Høgli JU Skjold F Småbrekke L 2015-06-01T00:00:00Z https://doaj.org/article/4c5ee8e1fc3e493cb6990ba424fa3dbe EN eng Centro de Investigaciones y Publicaciones Farmaceuticas http://www.pharmacypractice.org/journal/index.php/pp/article/view/575/394 https://doaj.org/toc/1885-642X https://doaj.org/toc/1886-3655 1885-642X 1886-3655 https://doaj.org/article/4c5ee8e1fc3e493cb6990ba424fa3dbe Pharmacy Practice, Vol 13, Iss 2, Pp 575-575 (2015) Pharmaceutical Services Medication Reconciliation Pharmacists Coronary Disease Randomized Controlled Trials as Topic Norway Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441 article 2015 ftdoajarticles 2022-12-30T22:05:59Z Objectives: The aim of the study was twofold; 1) to develop a clinical pharmacist-led 12 month lasting follow-up program for patients with established coronary heart disease (CHD) discharged from the University Hospital of North Norway, and 2) to explore the impact of the program with regards to adherence to a medication assessment tool for secondary prevention of CHD and change in biomedical risk factors. Methods: A total of 102 patients aged 18-82 years were enrolled in a non-blinded randomized controlled trial with an intervention group and a control group. The intervention comprised medication reconciliation, medication review and patient education during three meetings; at discharge, after three months and after twelve months. The control group received standard care from their general practitioner. Primary outcomes were adherence to clinical guideline recommendations concerning prescription, therapy goal achievement and lifestyle education defined in the medication assessment tool for secondary prevention of CHD (MAT-CHDSP). Secondary outcomes included changes in the biomedical risk factors cholesterol, blood pressure and blood glucose. Results: Ninety-four patients completed the trial, 48 intervention group patients and 46 controls. Appropriate prescribing was high, but therapy goal achievement was low in both groups. Overall adherence to MAT-CHDSP criteria increased in both groups and was significantly higher in the intervention group at study end, 78.4% vs. 62.0%, p<0.001. The difference was statistically significant for the documented lifestyle advices in intervention group patients. No significant improvements in biomedical risk factors were observed in favor of the intervention group. Conclusions: The study showed an increased guideline adherence in both study groups. This indicates that attention to clinical practice guideline recommendations in itself increases adherence – which may be a clinical pharmacist task. A larger adequately powered study is needed to show a significant difference in ... Article in Journal/Newspaper North Norway Directory of Open Access Journals: DOAJ Articles Norway |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Pharmaceutical Services Medication Reconciliation Pharmacists Coronary Disease Randomized Controlled Trials as Topic Norway Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441 |
spellingShingle |
Pharmaceutical Services Medication Reconciliation Pharmacists Coronary Disease Randomized Controlled Trials as Topic Norway Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441 Garcia BH Giverhaug T Høgli JU Skjold F Småbrekke L A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial |
topic_facet |
Pharmaceutical Services Medication Reconciliation Pharmacists Coronary Disease Randomized Controlled Trials as Topic Norway Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441 |
description |
Objectives: The aim of the study was twofold; 1) to develop a clinical pharmacist-led 12 month lasting follow-up program for patients with established coronary heart disease (CHD) discharged from the University Hospital of North Norway, and 2) to explore the impact of the program with regards to adherence to a medication assessment tool for secondary prevention of CHD and change in biomedical risk factors. Methods: A total of 102 patients aged 18-82 years were enrolled in a non-blinded randomized controlled trial with an intervention group and a control group. The intervention comprised medication reconciliation, medication review and patient education during three meetings; at discharge, after three months and after twelve months. The control group received standard care from their general practitioner. Primary outcomes were adherence to clinical guideline recommendations concerning prescription, therapy goal achievement and lifestyle education defined in the medication assessment tool for secondary prevention of CHD (MAT-CHDSP). Secondary outcomes included changes in the biomedical risk factors cholesterol, blood pressure and blood glucose. Results: Ninety-four patients completed the trial, 48 intervention group patients and 46 controls. Appropriate prescribing was high, but therapy goal achievement was low in both groups. Overall adherence to MAT-CHDSP criteria increased in both groups and was significantly higher in the intervention group at study end, 78.4% vs. 62.0%, p<0.001. The difference was statistically significant for the documented lifestyle advices in intervention group patients. No significant improvements in biomedical risk factors were observed in favor of the intervention group. Conclusions: The study showed an increased guideline adherence in both study groups. This indicates that attention to clinical practice guideline recommendations in itself increases adherence – which may be a clinical pharmacist task. A larger adequately powered study is needed to show a significant difference in ... |
format |
Article in Journal/Newspaper |
author |
Garcia BH Giverhaug T Høgli JU Skjold F Småbrekke L |
author_facet |
Garcia BH Giverhaug T Høgli JU Skjold F Småbrekke L |
author_sort |
Garcia BH |
title |
A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial |
title_short |
A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial |
title_full |
A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial |
title_fullStr |
A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial |
title_full_unstemmed |
A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial |
title_sort |
pharmacist-led follow-up program for patients with established coronary heart disease in north norway – a randomized controlled trial |
publisher |
Centro de Investigaciones y Publicaciones Farmaceuticas |
publishDate |
2015 |
url |
https://doaj.org/article/4c5ee8e1fc3e493cb6990ba424fa3dbe |
geographic |
Norway |
geographic_facet |
Norway |
genre |
North Norway |
genre_facet |
North Norway |
op_source |
Pharmacy Practice, Vol 13, Iss 2, Pp 575-575 (2015) |
op_relation |
http://www.pharmacypractice.org/journal/index.php/pp/article/view/575/394 https://doaj.org/toc/1885-642X https://doaj.org/toc/1886-3655 1885-642X 1886-3655 https://doaj.org/article/4c5ee8e1fc3e493cb6990ba424fa3dbe |
_version_ |
1766140113452007424 |