Co-infection of Dengue virus by serotypes 3 and 4 in patients from Amazonas, Brazil

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Regina M.P. de Figueiredo, Felipe Gomes Naveca, Cintia Mara Oliveira, Michele de Souza Bastos, Maria Paula Gomes Mourão, Suziane de S. Viana, Miriam do N. Melo, Evaulino F. Itapirema, Cassiano J. Saatkamp, Izeni P. Farias
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 2011
• Subjects: Brazil; Dengue; Co-infection; Flavivirus; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1590/S0036-46652011000600004; https://doaj.org/article/4bfe65621f3340b59a8955f16cf40fea

The natural co-infection with dengue virus can occur in highly endemic areas where different serotypes have been observed for many years. We report here four cases of DENV-3/DENV-4 co-infection detected by serological and molecular tests among 674 patients with acute undifferentiated fever from the tropical medicine reference center of Manaus City, Brazil, between 2005 and 2010. Analysis of the sequences obtained indicated the presence of genotype 3 and 1 for DENV-3 and DENV-4 respectively.