Co-infection of Dengue virus by serotypes 3 and 4 in patients from Amazonas, Brazil

The natural co-infection with dengue virus can occur in highly endemic areas where different serotypes have been observed for many years. We report here four cases of DENV-3/DENV-4 co-infection detected by serological and molecular tests among 674 patients with acute undifferentiated fever from the...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Regina M.P. de Figueiredo, Felipe Gomes Naveca, Cintia Mara Oliveira, Michele de Souza Bastos, Maria Paula Gomes Mourão, Suziane de S. Viana, Miriam do N. Melo, Evaulino F. Itapirema, Cassiano J. Saatkamp, Izeni P. Farias
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2011
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Online Access:https://doi.org/10.1590/S0036-46652011000600004
https://doaj.org/article/4bfe65621f3340b59a8955f16cf40fea
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Summary:The natural co-infection with dengue virus can occur in highly endemic areas where different serotypes have been observed for many years. We report here four cases of DENV-3/DENV-4 co-infection detected by serological and molecular tests among 674 patients with acute undifferentiated fever from the tropical medicine reference center of Manaus City, Brazil, between 2005 and 2010. Analysis of the sequences obtained indicated the presence of genotype 3 and 1 for DENV-3 and DENV-4 respectively.