A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM)
Abstract Coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM) is responsible for a high mortality rate due to its unique and severe host-pathogen interactions. Critically ill or immunocompromised COVID-19 patients are more prone to suffer from aggressive mycoses. Probable victims includ...
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ftdoajarticles:oai:doaj.org/article:4bbd17496a70412f82771d962bd45f31 2023-05-15T15:04:46+02:00 A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM) Nermin A. Osman Mohammed Moustapha Anwar Bivek Singh Girish K. Gupta Amgad M. Rabie 2023-03-01T00:00:00Z https://doi.org/10.1186/s42506-022-00125-1 https://doaj.org/article/4bbd17496a70412f82771d962bd45f31 EN eng SpringerOpen https://doi.org/10.1186/s42506-022-00125-1 https://doaj.org/toc/2090-262X doi:10.1186/s42506-022-00125-1 2090-262X https://doaj.org/article/4bbd17496a70412f82771d962bd45f31 Journal of the Egyptian Public Health Association, Vol 98, Iss 1, Pp 1-9 (2023) Mucormycosis COVID-19 CAM Multidisciplinary team Antifungal therapies Antimicrobial resistance Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles https://doi.org/10.1186/s42506-022-00125-1 2023-03-26T01:33:34Z Abstract Coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM) is responsible for a high mortality rate due to its unique and severe host-pathogen interactions. Critically ill or immunocompromised COVID-19 patients are more prone to suffer from aggressive mycoses. Probable victims include those with uncontrolled diabetes mellitus (DM), metabolic acidosis, prolonged neutropenia, increased ferritin levels, hypoxia, and prolonged hospitalization with/without mechanical ventilators and corticosteroids administration. The current review aims to outline the journey of patients with CAM as well as the advantages and disadvantages of the currently available diagnostic techniques. It also discussed the current status of treatment options and caveats in the management of mucormycosis. Multidisciplinary team, early diagnosis, controlling the predisposing condition(s), complete surgical debridement, effective antifungal therapies (e.g., amphotericin B, isavuconazole, and posaconazole), and implementing antifungal stewardship programs are imperative in CAM cases. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of the Egyptian Public Health Association 98 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Mucormycosis COVID-19 CAM Multidisciplinary team Antifungal therapies Antimicrobial resistance Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Mucormycosis COVID-19 CAM Multidisciplinary team Antifungal therapies Antimicrobial resistance Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Nermin A. Osman Mohammed Moustapha Anwar Bivek Singh Girish K. Gupta Amgad M. Rabie A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM) |
topic_facet |
Mucormycosis COVID-19 CAM Multidisciplinary team Antifungal therapies Antimicrobial resistance Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Abstract Coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM) is responsible for a high mortality rate due to its unique and severe host-pathogen interactions. Critically ill or immunocompromised COVID-19 patients are more prone to suffer from aggressive mycoses. Probable victims include those with uncontrolled diabetes mellitus (DM), metabolic acidosis, prolonged neutropenia, increased ferritin levels, hypoxia, and prolonged hospitalization with/without mechanical ventilators and corticosteroids administration. The current review aims to outline the journey of patients with CAM as well as the advantages and disadvantages of the currently available diagnostic techniques. It also discussed the current status of treatment options and caveats in the management of mucormycosis. Multidisciplinary team, early diagnosis, controlling the predisposing condition(s), complete surgical debridement, effective antifungal therapies (e.g., amphotericin B, isavuconazole, and posaconazole), and implementing antifungal stewardship programs are imperative in CAM cases. |
format |
Article in Journal/Newspaper |
author |
Nermin A. Osman Mohammed Moustapha Anwar Bivek Singh Girish K. Gupta Amgad M. Rabie |
author_facet |
Nermin A. Osman Mohammed Moustapha Anwar Bivek Singh Girish K. Gupta Amgad M. Rabie |
author_sort |
Nermin A. Osman |
title |
A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM) |
title_short |
A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM) |
title_full |
A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM) |
title_fullStr |
A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM) |
title_full_unstemmed |
A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM) |
title_sort |
peek behind the curtain in the diagnosis and management of covid‑19‑associated mucormycosis (cam) |
publisher |
SpringerOpen |
publishDate |
2023 |
url |
https://doi.org/10.1186/s42506-022-00125-1 https://doaj.org/article/4bbd17496a70412f82771d962bd45f31 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of the Egyptian Public Health Association, Vol 98, Iss 1, Pp 1-9 (2023) |
op_relation |
https://doi.org/10.1186/s42506-022-00125-1 https://doaj.org/toc/2090-262X doi:10.1186/s42506-022-00125-1 2090-262X https://doaj.org/article/4bbd17496a70412f82771d962bd45f31 |
op_doi |
https://doi.org/10.1186/s42506-022-00125-1 |
container_title |
Journal of the Egyptian Public Health Association |
container_volume |
98 |
container_issue |
1 |
_version_ |
1766336492174573568 |