Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats
Objective: To evaluate the antihyperglycemic potential of Tamarix aphylla (T. aphylla) leaves in STZ–NIC induced diabetes in Wister Albino rats. Methods: Acute toxicity study was done to check the toxicity of T. aphylla (L. Karst) methanol extract. T. aphylla leaves extract was administered intraper...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2017
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Online Access: | https://doi.org/10.1016/j.apjtb.2017.06.005 https://doaj.org/article/4b8d190434d1455086e95627ec20be30 |
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ftdoajarticles:oai:doaj.org/article:4b8d190434d1455086e95627ec20be30 2023-05-15T15:04:03+02:00 Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats Rooh Ullah Shafiq Ahmed Tariq Naeem Khan Nawaz Sharif Zia Ud Din Khalid Mansoor 2017-07-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2017.06.005 https://doaj.org/article/4b8d190434d1455086e95627ec20be30 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169116303756 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.06.005 https://doaj.org/article/4b8d190434d1455086e95627ec20be30 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 7, Pp 619-623 (2017) Tamarix aphylla leaves Diabetes Streptozotocin Antidiabetic potential Insulin secretion Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2017.06.005 2022-12-30T21:52:12Z Objective: To evaluate the antihyperglycemic potential of Tamarix aphylla (T. aphylla) leaves in STZ–NIC induced diabetes in Wister Albino rats. Methods: Acute toxicity study was done to check the toxicity of T. aphylla (L. Karst) methanol extract. T. aphylla leaves extract was administered intraperitoneally (100 mg, 250 mg and 400 mg/kg body weight per day) to diabetic Wister rats for 21 days. The various parameters were studied including fasting blood glucose levels, haemoglobin and glycosylated haemoglobin. Results: The treatment groups with the extract at three dose levels expressively abridged the intensities of blood glucose and Glycosylated Haemoglobin. The earlier detected reduced level of plasma haemoglobin of the diabetic rats was raised to near normalcy with treatment of extract. Conclusions: The results of the current study confirm that the leaves extract of T. aphylla are nontoxic and have antidiabetic nature. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 7 619 623 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Tamarix aphylla leaves Diabetes Streptozotocin Antidiabetic potential Insulin secretion Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Tamarix aphylla leaves Diabetes Streptozotocin Antidiabetic potential Insulin secretion Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Rooh Ullah Shafiq Ahmed Tariq Naeem Khan Nawaz Sharif Zia Ud Din Khalid Mansoor Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats |
topic_facet |
Tamarix aphylla leaves Diabetes Streptozotocin Antidiabetic potential Insulin secretion Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To evaluate the antihyperglycemic potential of Tamarix aphylla (T. aphylla) leaves in STZ–NIC induced diabetes in Wister Albino rats. Methods: Acute toxicity study was done to check the toxicity of T. aphylla (L. Karst) methanol extract. T. aphylla leaves extract was administered intraperitoneally (100 mg, 250 mg and 400 mg/kg body weight per day) to diabetic Wister rats for 21 days. The various parameters were studied including fasting blood glucose levels, haemoglobin and glycosylated haemoglobin. Results: The treatment groups with the extract at three dose levels expressively abridged the intensities of blood glucose and Glycosylated Haemoglobin. The earlier detected reduced level of plasma haemoglobin of the diabetic rats was raised to near normalcy with treatment of extract. Conclusions: The results of the current study confirm that the leaves extract of T. aphylla are nontoxic and have antidiabetic nature. |
format |
Article in Journal/Newspaper |
author |
Rooh Ullah Shafiq Ahmed Tariq Naeem Khan Nawaz Sharif Zia Ud Din Khalid Mansoor |
author_facet |
Rooh Ullah Shafiq Ahmed Tariq Naeem Khan Nawaz Sharif Zia Ud Din Khalid Mansoor |
author_sort |
Rooh Ullah |
title |
Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats |
title_short |
Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats |
title_full |
Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats |
title_fullStr |
Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats |
title_full_unstemmed |
Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats |
title_sort |
antihyperglycemic effect of methanol extract of tamarix aphylla l. karst (saltcedar) in streptozocin–nicotinamide induced diabetic rats |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2017.06.005 https://doaj.org/article/4b8d190434d1455086e95627ec20be30 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 7, Pp 619-623 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169116303756 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.06.005 https://doaj.org/article/4b8d190434d1455086e95627ec20be30 |
op_doi |
https://doi.org/10.1016/j.apjtb.2017.06.005 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
7 |
container_start_page |
619 |
op_container_end_page |
623 |
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1766335875726180352 |