Leptospirosis in animals and human contacts in Egypt: broad range surveillance
INTRODUCTION: Leptospirosis is a re-emerging zoonotic disease of humans and animals worldwide. The disease is caused by pathogenic species of the genus Leptospira. These organisms are maintained in nature via chronic renal infection of carrier animals, which excrete the organisms in their urine. Hum...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
---|---|
Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
2015
|
Subjects: | |
Online Access: | https://doi.org/10.1590/0037-8682-0102-2015 https://doaj.org/article/4a60aac49af04eeab35f4573dc7de645 |
id |
ftdoajarticles:oai:doaj.org/article:4a60aac49af04eeab35f4573dc7de645 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:4a60aac49af04eeab35f4573dc7de645 2023-05-15T15:12:43+02:00 Leptospirosis in animals and human contacts in Egypt: broad range surveillance Ahmed Samir Rafik Soliman Mahmoud El-Hariri Khaled Abdel-Moein Mahmoud Essam Hatem 2015-06-01T00:00:00Z https://doi.org/10.1590/0037-8682-0102-2015 https://doaj.org/article/4a60aac49af04eeab35f4573dc7de645 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000300272&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0102-2015 https://doaj.org/article/4a60aac49af04eeab35f4573dc7de645 Revista da Sociedade Brasileira de Medicina Tropical, Vol 48, Iss 3, Pp 272-277 (2015) Leptospirosis Zoonosis Egypt Arctic medicine. Tropical medicine RC955-962 article 2015 ftdoajarticles https://doi.org/10.1590/0037-8682-0102-2015 2022-12-31T02:35:47Z INTRODUCTION: Leptospirosis is a re-emerging zoonotic disease of humans and animals worldwide. The disease is caused by pathogenic species of the genus Leptospira. These organisms are maintained in nature via chronic renal infection of carrier animals, which excrete the organisms in their urine. Humans become infected through direct or indirect exposure to infected animals and their urine or through contact with contaminated water and soil. This study was conducted to investigate Leptospira infections as a re-emerging zoonosis that has been neglected in Egypt. METHODS: Samples from 1,250 animals (270 rats, 168 dogs, 625 cows, 26 buffaloes, 99 sheep, 14 horses, 26 donkeys and 22 camels), 175 human contacts and 45 water sources were collected from different governorates in Egypt. The samples were collected from different body sites and prepared for culture, PCR and the microscopic agglutination test (MAT). RESULTS: The isolation rates of Leptospira serovars were 6.9%, 11.3% and 1.1% for rats, dogs and cows, respectively, whereas the PCR results revealed respective detection rates of 24%, 11.3% and 1.1% for rats, dogs and cows. Neither the other examined animal species nor humans yielded positive results via these two techniques. Only six Leptospira serovars (Icterohaemorrhagiae, Pomona, Canicola, Grippotyphosa, Celledoni and Pyrogenes) could be isolated from rats, dogs and cows. Moreover, the seroprevalence of leptospiral antibodies among the examined humans determined using MAT was 49.7%. CONCLUSIONS: The obtained results revealed that rats, dogs and cows were the most important animal reservoirs for leptospirosis in Egypt, and the high seroprevalence among human contacts highlights the public health implications of this neglected zoonosis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pomona ENVELOPE(-45.900,-45.900,-60.583,-60.583) Revista da Sociedade Brasileira de Medicina Tropical 48 3 272 277 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Leptospirosis Zoonosis Egypt Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Leptospirosis Zoonosis Egypt Arctic medicine. Tropical medicine RC955-962 Ahmed Samir Rafik Soliman Mahmoud El-Hariri Khaled Abdel-Moein Mahmoud Essam Hatem Leptospirosis in animals and human contacts in Egypt: broad range surveillance |
topic_facet |
Leptospirosis Zoonosis Egypt Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: Leptospirosis is a re-emerging zoonotic disease of humans and animals worldwide. The disease is caused by pathogenic species of the genus Leptospira. These organisms are maintained in nature via chronic renal infection of carrier animals, which excrete the organisms in their urine. Humans become infected through direct or indirect exposure to infected animals and their urine or through contact with contaminated water and soil. This study was conducted to investigate Leptospira infections as a re-emerging zoonosis that has been neglected in Egypt. METHODS: Samples from 1,250 animals (270 rats, 168 dogs, 625 cows, 26 buffaloes, 99 sheep, 14 horses, 26 donkeys and 22 camels), 175 human contacts and 45 water sources were collected from different governorates in Egypt. The samples were collected from different body sites and prepared for culture, PCR and the microscopic agglutination test (MAT). RESULTS: The isolation rates of Leptospira serovars were 6.9%, 11.3% and 1.1% for rats, dogs and cows, respectively, whereas the PCR results revealed respective detection rates of 24%, 11.3% and 1.1% for rats, dogs and cows. Neither the other examined animal species nor humans yielded positive results via these two techniques. Only six Leptospira serovars (Icterohaemorrhagiae, Pomona, Canicola, Grippotyphosa, Celledoni and Pyrogenes) could be isolated from rats, dogs and cows. Moreover, the seroprevalence of leptospiral antibodies among the examined humans determined using MAT was 49.7%. CONCLUSIONS: The obtained results revealed that rats, dogs and cows were the most important animal reservoirs for leptospirosis in Egypt, and the high seroprevalence among human contacts highlights the public health implications of this neglected zoonosis. |
format |
Article in Journal/Newspaper |
author |
Ahmed Samir Rafik Soliman Mahmoud El-Hariri Khaled Abdel-Moein Mahmoud Essam Hatem |
author_facet |
Ahmed Samir Rafik Soliman Mahmoud El-Hariri Khaled Abdel-Moein Mahmoud Essam Hatem |
author_sort |
Ahmed Samir |
title |
Leptospirosis in animals and human contacts in Egypt: broad range surveillance |
title_short |
Leptospirosis in animals and human contacts in Egypt: broad range surveillance |
title_full |
Leptospirosis in animals and human contacts in Egypt: broad range surveillance |
title_fullStr |
Leptospirosis in animals and human contacts in Egypt: broad range surveillance |
title_full_unstemmed |
Leptospirosis in animals and human contacts in Egypt: broad range surveillance |
title_sort |
leptospirosis in animals and human contacts in egypt: broad range surveillance |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2015 |
url |
https://doi.org/10.1590/0037-8682-0102-2015 https://doaj.org/article/4a60aac49af04eeab35f4573dc7de645 |
long_lat |
ENVELOPE(-45.900,-45.900,-60.583,-60.583) |
geographic |
Arctic Pomona |
geographic_facet |
Arctic Pomona |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 48, Iss 3, Pp 272-277 (2015) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000300272&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0102-2015 https://doaj.org/article/4a60aac49af04eeab35f4573dc7de645 |
op_doi |
https://doi.org/10.1590/0037-8682-0102-2015 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
48 |
container_issue |
3 |
container_start_page |
272 |
op_container_end_page |
277 |
_version_ |
1766343366401851392 |