Characterization of Rift Valley fever virus MP-12 strain encoding NSs of Punta Toro virus or sandfly fever Sicilian virus.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: Olga A Lihoradova, Sabarish V Indran, Birte Kalveram, Nandadeva Lokugamage, Jennifer A Head, Bin Gong, Bersabeh Tigabu, Terry L Juelich, Alexander N Freiberg, Tetsuro Ikegami
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2013
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Punta Toro
• Online Access: https://doi.org/10.1371/journal.pntd.0002181; https://doaj.org/article/4a253b2f3e214ba99bc1b54a086cb910

Rift Valley fever virus (RVFV; genus Phlebovirus, family Bunyaviridae) is a mosquito-borne zoonotic pathogen which can cause hemorrhagic fever, neurological disorders or blindness in humans, and a high rate of abortion in ruminants. MP-12 strain, a live-attenuated candidate vaccine, is attenuated in...