Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru
OBJECTIVES: Cervical cancer is the leading cause of cancer death among women in developing countries. This study was designed to evaluate whether visual inspection with acetic acid and magnification (VIAM) improved confirmation of cervical lesions as compared to confirmation with visual inspection w...
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ftdoajarticles:oai:doaj.org/article:49ed779f48e94cba9cb9160827c109d5 2023-05-15T15:08:38+02:00 Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru Jennifer L. Winkler Kristen Lewis Roberto Del Aguila Miguel Gonzales José Manuel Delgado Vivien D. Tsu John W. Sellors 2008-01-01T00:00:00Z https://doi.org/10.1590/s1020-49892008000100001 https://doaj.org/article/49ed779f48e94cba9cb9160827c109d5 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892008000100001&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49892008000100001 https://doaj.org/article/49ed779f48e94cba9cb9160827c109d5 Revista Panamericana de Salud Pública, Vol 23, Iss 1, Pp 1-6 (2008) Neoplasmas del cuello uterino diagnóstico cribado Perú Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2008 ftdoajarticles https://doi.org/10.1590/s1020-49892008000100001 2022-12-31T09:00:15Z OBJECTIVES: Cervical cancer is the leading cause of cancer death among women in developing countries. This study was designed to evaluate whether visual inspection with acetic acid and magnification (VIAM) improved confirmation of cervical lesions as compared to confirmation with visual inspection with acetic acid (VIA) without magnification when used by physicians. METHODS: From April-December 2004, women in San Martin, Peru, who were referred as VIA-positive by an "obstetriz" (a professional midwife with 6 years of university training) were randomized into two groups for confirmatory screening by a physician using either VIA or VIAM with an AviScope,TM a hand-held 4x magnification scope with a green light source. The reference standard for the presence or absence of cervical neoplasia was colposcopy and directed biopsy, as required. RESULTS: A total of 358 women participated in the study; 161 had a confirmatory examination with VIAM and 159 with VIA. Sensitivity for low- or high-grade lesions was 68% with VIA and 77% with VIAM, and specificity was 62% with VIA and 63% with VIAM; however, these differences were not statistically significant. CONCLUSIONS: For settings where physician confirmation of cervical abnormalities identified through visual inspection is required and available, this study demonstrates that VIAM had no significant advantage over VIA. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista Panamericana de Salud Pública 23 1 1 6 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English Spanish Portuguese |
topic |
Neoplasmas del cuello uterino diagnóstico cribado Perú Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Neoplasmas del cuello uterino diagnóstico cribado Perú Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Jennifer L. Winkler Kristen Lewis Roberto Del Aguila Miguel Gonzales José Manuel Delgado Vivien D. Tsu John W. Sellors Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru |
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Neoplasmas del cuello uterino diagnóstico cribado Perú Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
OBJECTIVES: Cervical cancer is the leading cause of cancer death among women in developing countries. This study was designed to evaluate whether visual inspection with acetic acid and magnification (VIAM) improved confirmation of cervical lesions as compared to confirmation with visual inspection with acetic acid (VIA) without magnification when used by physicians. METHODS: From April-December 2004, women in San Martin, Peru, who were referred as VIA-positive by an "obstetriz" (a professional midwife with 6 years of university training) were randomized into two groups for confirmatory screening by a physician using either VIA or VIAM with an AviScope,TM a hand-held 4x magnification scope with a green light source. The reference standard for the presence or absence of cervical neoplasia was colposcopy and directed biopsy, as required. RESULTS: A total of 358 women participated in the study; 161 had a confirmatory examination with VIAM and 159 with VIA. Sensitivity for low- or high-grade lesions was 68% with VIA and 77% with VIAM, and specificity was 62% with VIA and 63% with VIAM; however, these differences were not statistically significant. CONCLUSIONS: For settings where physician confirmation of cervical abnormalities identified through visual inspection is required and available, this study demonstrates that VIAM had no significant advantage over VIA. |
format |
Article in Journal/Newspaper |
author |
Jennifer L. Winkler Kristen Lewis Roberto Del Aguila Miguel Gonzales José Manuel Delgado Vivien D. Tsu John W. Sellors |
author_facet |
Jennifer L. Winkler Kristen Lewis Roberto Del Aguila Miguel Gonzales José Manuel Delgado Vivien D. Tsu John W. Sellors |
author_sort |
Jennifer L. Winkler |
title |
Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru |
title_short |
Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru |
title_full |
Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru |
title_fullStr |
Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru |
title_full_unstemmed |
Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru |
title_sort |
is magnification necessary to confirm visual inspection of cervical abnormalities? a randomized trial in peru |
publisher |
Pan American Health Organization |
publishDate |
2008 |
url |
https://doi.org/10.1590/s1020-49892008000100001 https://doaj.org/article/49ed779f48e94cba9cb9160827c109d5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 23, Iss 1, Pp 1-6 (2008) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892008000100001&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49892008000100001 https://doaj.org/article/49ed779f48e94cba9cb9160827c109d5 |
op_doi |
https://doi.org/10.1590/s1020-49892008000100001 |
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Revista Panamericana de Salud Pública |
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23 |
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6 |
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