Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran
Objective: To determine the seroprevalance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the general population of Mazandaran province in Iran and to estimate the percentage of asymptomatic, mild, and severe infections. Methods: We chose 1 588 inhabitants of Mazandara...
Published in: | Asian Pacific Journal of Tropical Medicine |
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Wolters Kluwer Medknow Publications
2021
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Online Access: | https://doi.org/10.4103/1995-7645.304296 https://doaj.org/article/48cb4fc3983b49ac8c3c9fea44fc7160 |
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ftdoajarticles:oai:doaj.org/article:48cb4fc3983b49ac8c3c9fea44fc7160 2023-05-15T15:13:19+02:00 Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran Seyed Abbas Mousavi Hamed Rouhanizadeh Majid Saeedi Mahmood Moosazadeh Abolqasem Ajami Afsaneh Fendereski Jamshid Yazdani-Charati Seyed Mohsen Soleimani Nader Ahangar Seyed Hossein Seyedpour Zahra Bandalizaeh 2021-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.304296 https://doaj.org/article/48cb4fc3983b49ac8c3c9fea44fc7160 EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2021;volume=14;issue=1;spage=10;epage=16;aulast=Mousavi https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.304296 https://doaj.org/article/48cb4fc3983b49ac8c3c9fea44fc7160 Asian Pacific Journal of Tropical Medicine, Vol 14, Iss 1, Pp 10-16 (2021) sars-cov-2 covid-19 prevalance iran serology igm igg Arctic medicine. Tropical medicine RC955-962 article 2021 ftdoajarticles https://doi.org/10.4103/1995-7645.304296 2022-12-30T20:39:25Z Objective: To determine the seroprevalance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the general population of Mazandaran province in Iran and to estimate the percentage of asymptomatic, mild, and severe infections. Methods: We chose 1 588 inhabitants of Mazandaran province with cluster sampling. We measured their SARS-CoV-2 immunoglobulin M (IgM) and immunoglobulin G (IgG) serum levels. Demographics, risk factors, and symptoms were collected. The seroprevalence of SARS-CoV-2 was calculated by age and city and the World Health Organization (WHO) protocol and further stratified by demographic variables and risk factors. Finally, we identified the symptoms and factors related to COVID-19 with logistic regression. Results: Two hundred subjects (12.59%) were tested positive for either IgG or IgM. Until May 23, 2020, the prevalence of COVID-19 was 15.26% (95% CI: 12.97%-17.79%) based on direct standardization and WHO’s standardized age groups. Based on multivariate logistic regression, the incidence of getting an infection increased by an average of 11.6% for every 10-year increase in age (OR=1.116, 95% CI: 1.008-1.236, P=0.035). Furthermore, those in contact with COVID-19 patients had a 66.1% higher risk of developing the disease (OR=1.661, 95% CI: 1.104-2.497, P=0.015). In addition, the chance of getting SARS-CoV-2 infection was almost four times higher in people who had consulted a doctor during the pandemic than those who had not (OR=3.942, 95% CI: 2.813-5.524, P<0.001). Conclusions: The prevalence of COVID-19 in Mazandaran province could be higher than the officially reported statistics based on diagnostic tests and clinical cases. There seems to be more asymptomatic or mild symptom cases than what was previously reported. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Medicine 14 1 10 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
sars-cov-2 covid-19 prevalance iran serology igm igg Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
sars-cov-2 covid-19 prevalance iran serology igm igg Arctic medicine. Tropical medicine RC955-962 Seyed Abbas Mousavi Hamed Rouhanizadeh Majid Saeedi Mahmood Moosazadeh Abolqasem Ajami Afsaneh Fendereski Jamshid Yazdani-Charati Seyed Mohsen Soleimani Nader Ahangar Seyed Hossein Seyedpour Zahra Bandalizaeh Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran |
topic_facet |
sars-cov-2 covid-19 prevalance iran serology igm igg Arctic medicine. Tropical medicine RC955-962 |
description |
Objective: To determine the seroprevalance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the general population of Mazandaran province in Iran and to estimate the percentage of asymptomatic, mild, and severe infections. Methods: We chose 1 588 inhabitants of Mazandaran province with cluster sampling. We measured their SARS-CoV-2 immunoglobulin M (IgM) and immunoglobulin G (IgG) serum levels. Demographics, risk factors, and symptoms were collected. The seroprevalence of SARS-CoV-2 was calculated by age and city and the World Health Organization (WHO) protocol and further stratified by demographic variables and risk factors. Finally, we identified the symptoms and factors related to COVID-19 with logistic regression. Results: Two hundred subjects (12.59%) were tested positive for either IgG or IgM. Until May 23, 2020, the prevalence of COVID-19 was 15.26% (95% CI: 12.97%-17.79%) based on direct standardization and WHO’s standardized age groups. Based on multivariate logistic regression, the incidence of getting an infection increased by an average of 11.6% for every 10-year increase in age (OR=1.116, 95% CI: 1.008-1.236, P=0.035). Furthermore, those in contact with COVID-19 patients had a 66.1% higher risk of developing the disease (OR=1.661, 95% CI: 1.104-2.497, P=0.015). In addition, the chance of getting SARS-CoV-2 infection was almost four times higher in people who had consulted a doctor during the pandemic than those who had not (OR=3.942, 95% CI: 2.813-5.524, P<0.001). Conclusions: The prevalence of COVID-19 in Mazandaran province could be higher than the officially reported statistics based on diagnostic tests and clinical cases. There seems to be more asymptomatic or mild symptom cases than what was previously reported. |
format |
Article in Journal/Newspaper |
author |
Seyed Abbas Mousavi Hamed Rouhanizadeh Majid Saeedi Mahmood Moosazadeh Abolqasem Ajami Afsaneh Fendereski Jamshid Yazdani-Charati Seyed Mohsen Soleimani Nader Ahangar Seyed Hossein Seyedpour Zahra Bandalizaeh |
author_facet |
Seyed Abbas Mousavi Hamed Rouhanizadeh Majid Saeedi Mahmood Moosazadeh Abolqasem Ajami Afsaneh Fendereski Jamshid Yazdani-Charati Seyed Mohsen Soleimani Nader Ahangar Seyed Hossein Seyedpour Zahra Bandalizaeh |
author_sort |
Seyed Abbas Mousavi |
title |
Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran |
title_short |
Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran |
title_full |
Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran |
title_fullStr |
Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran |
title_full_unstemmed |
Seroprevalence of SARS-CoV-2 in Mazandaran province, Iran |
title_sort |
seroprevalence of sars-cov-2 in mazandaran province, iran |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2021 |
url |
https://doi.org/10.4103/1995-7645.304296 https://doaj.org/article/48cb4fc3983b49ac8c3c9fea44fc7160 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 14, Iss 1, Pp 10-16 (2021) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2021;volume=14;issue=1;spage=10;epage=16;aulast=Mousavi https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.304296 https://doaj.org/article/48cb4fc3983b49ac8c3c9fea44fc7160 |
op_doi |
https://doi.org/10.4103/1995-7645.304296 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
14 |
container_issue |
1 |
container_start_page |
10 |
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1766343882007642112 |