Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation
Marisa Antunes,1 Aleksander Baumgärtel,2 Petter Fosse Gjessing,3 Lars Marius Ytrebø1 1Department of Anaesthesiology, University Hospital of North Norway and Institute of Clinical Medicine, Acute and Critical Care Research Group, UiT – the Arctic University of Norway, Tromsø, Norway; 2Institute of Cl...
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ftdoajarticles:oai:doaj.org/article:483c2fa0eb3e4bc890cb577b798225cb 2023-06-18T03:42:13+02:00 Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation Antunes M Baumgärtel A Gjessing PF Ytrebø LM 2023-05-01T00:00:00Z https://doaj.org/article/483c2fa0eb3e4bc890cb577b798225cb EN eng Dove Medical Press https://www.dovepress.com/spinal-anaesthesia-as-an-adjunct-to-general-anaesthesia-for-laparoscop-peer-reviewed-fulltext-article-JPR https://doaj.org/toc/1178-7090 1178-7090 https://doaj.org/article/483c2fa0eb3e4bc890cb577b798225cb Journal of Pain Research, Vol Volume 16, Pp 1855-1865 (2023) anesthesiology opioid consumption rectal amputation spinal anesthesia surgery Medicine (General) R5-920 article 2023 ftdoajarticles 2023-06-04T00:34:02Z Marisa Antunes,1 Aleksander Baumgärtel,2 Petter Fosse Gjessing,3 Lars Marius Ytrebø1 1Department of Anaesthesiology, University Hospital of North Norway and Institute of Clinical Medicine, Acute and Critical Care Research Group, UiT – the Arctic University of Norway, Tromsø, Norway; 2Institute of Clinical Medicine, Acute and Critical Care Research group, UiT – the Arctic University of Norway, Tromsø, Norway; 3Department of Digestive Surgery, University Hospital of North Norway and Institute of Clinical Medicine, Gastro Surgery Research group, UiT – the Arctic University of Norway, Tromsø, NorwayCorrespondence: Lars Marius Ytrebø, Department of Anaesthesiology, University Hospital of North Norway and Acute and Critical Care Research Group, UiT – the Arctic University of Norway, Tromsø, Norway, Tel +47 90788058, Fax +4777626192, Email lars.marius.ytrebo@unn.noBackground: Spinal anaesthesia as an adjunct to general anaesthesia may reduce postoperative pain and opioid consumption after laparoscopic abdominoperineal rectal amputation. We designed a randomized double blinded pilot study with two objectives: 1) to explore potential benefits of spinal anaesthesia as an adjunct to general anaesthesia and 2) to provide power and sample size estimations for potential differences between the groups. Primary outcome measures were postoperative pain and oral morphine equivalent (OMEq) consumption.Methods: Patients scheduled for elective laparoscopic abdominoperineal rectal amputation at the University Hospital of North Norway were randomised to spinal (n=5) or a sham spinal procedure (n=5). Numeric rating scale (NRS) and OMEq were monitored postoperatively for 72 h.Results: Age, sex, body mass index, and ASA were not significantly different between the groups. During surgery, patients in the spinal group received less remifentanil (p=0.06). NRS was lower in the spinal group 1 hr after admittance to the post-anaesthesia care unit (PACU) (p=0.06) and on the first postoperative day at 8 AM (p=0.03). OMEq consumption in the PACU ... Article in Journal/Newspaper North Norway Tromsø Arctic University of Norway UiT The Arctic University of Norway Directory of Open Access Journals: DOAJ Articles Arctic Fosse ENVELOPE(19.182,19.182,69.959,69.959) Norway Tromsø Ytrebø ENVELOPE(9.633,9.633,63.683,63.683) |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
anesthesiology opioid consumption rectal amputation spinal anesthesia surgery Medicine (General) R5-920 |
spellingShingle |
anesthesiology opioid consumption rectal amputation spinal anesthesia surgery Medicine (General) R5-920 Antunes M Baumgärtel A Gjessing PF Ytrebø LM Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation |
topic_facet |
anesthesiology opioid consumption rectal amputation spinal anesthesia surgery Medicine (General) R5-920 |
description |
Marisa Antunes,1 Aleksander Baumgärtel,2 Petter Fosse Gjessing,3 Lars Marius Ytrebø1 1Department of Anaesthesiology, University Hospital of North Norway and Institute of Clinical Medicine, Acute and Critical Care Research Group, UiT – the Arctic University of Norway, Tromsø, Norway; 2Institute of Clinical Medicine, Acute and Critical Care Research group, UiT – the Arctic University of Norway, Tromsø, Norway; 3Department of Digestive Surgery, University Hospital of North Norway and Institute of Clinical Medicine, Gastro Surgery Research group, UiT – the Arctic University of Norway, Tromsø, NorwayCorrespondence: Lars Marius Ytrebø, Department of Anaesthesiology, University Hospital of North Norway and Acute and Critical Care Research Group, UiT – the Arctic University of Norway, Tromsø, Norway, Tel +47 90788058, Fax +4777626192, Email lars.marius.ytrebo@unn.noBackground: Spinal anaesthesia as an adjunct to general anaesthesia may reduce postoperative pain and opioid consumption after laparoscopic abdominoperineal rectal amputation. We designed a randomized double blinded pilot study with two objectives: 1) to explore potential benefits of spinal anaesthesia as an adjunct to general anaesthesia and 2) to provide power and sample size estimations for potential differences between the groups. Primary outcome measures were postoperative pain and oral morphine equivalent (OMEq) consumption.Methods: Patients scheduled for elective laparoscopic abdominoperineal rectal amputation at the University Hospital of North Norway were randomised to spinal (n=5) or a sham spinal procedure (n=5). Numeric rating scale (NRS) and OMEq were monitored postoperatively for 72 h.Results: Age, sex, body mass index, and ASA were not significantly different between the groups. During surgery, patients in the spinal group received less remifentanil (p=0.06). NRS was lower in the spinal group 1 hr after admittance to the post-anaesthesia care unit (PACU) (p=0.06) and on the first postoperative day at 8 AM (p=0.03). OMEq consumption in the PACU ... |
format |
Article in Journal/Newspaper |
author |
Antunes M Baumgärtel A Gjessing PF Ytrebø LM |
author_facet |
Antunes M Baumgärtel A Gjessing PF Ytrebø LM |
author_sort |
Antunes M |
title |
Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation |
title_short |
Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation |
title_full |
Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation |
title_fullStr |
Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation |
title_full_unstemmed |
Spinal Anaesthesia as an Adjunct to General Anaesthesia for Laparoscopic Abdominoperineal Rectal Amputation |
title_sort |
spinal anaesthesia as an adjunct to general anaesthesia for laparoscopic abdominoperineal rectal amputation |
publisher |
Dove Medical Press |
publishDate |
2023 |
url |
https://doaj.org/article/483c2fa0eb3e4bc890cb577b798225cb |
long_lat |
ENVELOPE(19.182,19.182,69.959,69.959) ENVELOPE(9.633,9.633,63.683,63.683) |
geographic |
Arctic Fosse Norway Tromsø Ytrebø |
geographic_facet |
Arctic Fosse Norway Tromsø Ytrebø |
genre |
North Norway Tromsø Arctic University of Norway UiT The Arctic University of Norway |
genre_facet |
North Norway Tromsø Arctic University of Norway UiT The Arctic University of Norway |
op_source |
Journal of Pain Research, Vol Volume 16, Pp 1855-1865 (2023) |
op_relation |
https://www.dovepress.com/spinal-anaesthesia-as-an-adjunct-to-general-anaesthesia-for-laparoscop-peer-reviewed-fulltext-article-JPR https://doaj.org/toc/1178-7090 1178-7090 https://doaj.org/article/483c2fa0eb3e4bc890cb577b798225cb |
_version_ |
1769008086757933056 |