Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation
IntroductionDespite high diabetes rates among Canadian First Nations people, little is known about their cardiovascular disease risk. Our aim was to describe the apolipoprotein profile with respect to cardiovascular risk in a Canadian First Nation community.MethodsIn 2003, a representative sample of...
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ftdoajarticles:oai:doaj.org/article:476fd84bc9704e9c8be398eb9279a0b6 2023-11-05T03:41:59+01:00 Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation Natalie D. Riediger, MSc Sharon G. Bruce, PhD T. Kue Young, MD, DPhil 2011-01-01T00:00:00Z https://doaj.org/article/476fd84bc9704e9c8be398eb9279a0b6 EN eng Centers for Disease Control and Prevention http://www.cdc.gov/pcd/issues/2011/jan/09_0216.htm https://doaj.org/toc/1545-1151 1545-1151 https://doaj.org/article/476fd84bc9704e9c8be398eb9279a0b6 Preventing Chronic Disease, Vol 8, Iss 1 (2011) cardiovascular risk plasma apolipoprotein lipid profiles Canadian First Nation Public aspects of medicine RA1-1270 article 2011 ftdoajarticles 2023-10-08T00:38:45Z IntroductionDespite high diabetes rates among Canadian First Nations people, little is known about their cardiovascular disease risk. Our aim was to describe the apolipoprotein profile with respect to cardiovascular risk in a Canadian First Nation community.MethodsIn 2003, a representative sample of adult members of a Manitoba First Nation (N = 483) participated in a screening study for diabetes and diabetes complications. We assessed their cardiovascular risk factors.ResultsSixty percent of women were at increased cardiovascular risk because of low apolipoprotein A1 (apoA1) levels, compared with 35% of men. The proportion of women with low apoA1 levels decreased with age, but the proportion with low high-density lipoprotein levels remained stable across age groups. Both apoB and apoA1 were significantly associated with obesity when age, sex, diastolic blood pressure, homocysteine, diabetes, and insulin resistance were controlled for.ConclusionApolipoprotein and lipid profiles in this First Nation population suggest high cardiovascular risk. Future research should characterize the lipoprotein particle size in this population. Article in Journal/Newspaper First Nations Directory of Open Access Journals: DOAJ Articles |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
cardiovascular risk plasma apolipoprotein lipid profiles Canadian First Nation Public aspects of medicine RA1-1270 |
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cardiovascular risk plasma apolipoprotein lipid profiles Canadian First Nation Public aspects of medicine RA1-1270 Natalie D. Riediger, MSc Sharon G. Bruce, PhD T. Kue Young, MD, DPhil Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation |
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cardiovascular risk plasma apolipoprotein lipid profiles Canadian First Nation Public aspects of medicine RA1-1270 |
description |
IntroductionDespite high diabetes rates among Canadian First Nations people, little is known about their cardiovascular disease risk. Our aim was to describe the apolipoprotein profile with respect to cardiovascular risk in a Canadian First Nation community.MethodsIn 2003, a representative sample of adult members of a Manitoba First Nation (N = 483) participated in a screening study for diabetes and diabetes complications. We assessed their cardiovascular risk factors.ResultsSixty percent of women were at increased cardiovascular risk because of low apolipoprotein A1 (apoA1) levels, compared with 35% of men. The proportion of women with low apoA1 levels decreased with age, but the proportion with low high-density lipoprotein levels remained stable across age groups. Both apoB and apoA1 were significantly associated with obesity when age, sex, diastolic blood pressure, homocysteine, diabetes, and insulin resistance were controlled for.ConclusionApolipoprotein and lipid profiles in this First Nation population suggest high cardiovascular risk. Future research should characterize the lipoprotein particle size in this population. |
format |
Article in Journal/Newspaper |
author |
Natalie D. Riediger, MSc Sharon G. Bruce, PhD T. Kue Young, MD, DPhil |
author_facet |
Natalie D. Riediger, MSc Sharon G. Bruce, PhD T. Kue Young, MD, DPhil |
author_sort |
Natalie D. Riediger, MSc |
title |
Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation |
title_short |
Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation |
title_full |
Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation |
title_fullStr |
Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation |
title_full_unstemmed |
Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation |
title_sort |
cardiovascular risk according to plasma apolipoprotein and lipid profiles in a canadian first nation |
publisher |
Centers for Disease Control and Prevention |
publishDate |
2011 |
url |
https://doaj.org/article/476fd84bc9704e9c8be398eb9279a0b6 |
genre |
First Nations |
genre_facet |
First Nations |
op_source |
Preventing Chronic Disease, Vol 8, Iss 1 (2011) |
op_relation |
http://www.cdc.gov/pcd/issues/2011/jan/09_0216.htm https://doaj.org/toc/1545-1151 1545-1151 https://doaj.org/article/476fd84bc9704e9c8be398eb9279a0b6 |
_version_ |
1781698779849687040 |