Time to reconsider the role of ribavirin in Lassa fever.

Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some Lassa fever patients. An urgent reevaluation o...

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Published in:PLOS Neglected Tropical Diseases
Main Authors: Alex Paddy Salam, Vincent Cheng, Tansy Edwards, Piero Olliaro, Jonathan Sterne, Peter Horby
Format: Article in Journal/Newspaper
Language:English
Published: Public Library of Science (PLoS) 2021
Subjects:
Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Arctic
Online Access:https://doi.org/10.1371/journal.pntd.0009522
https://doaj.org/article/4763774884534bc790cd73d9a203fb9a
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spelling ftdoajarticles:oai:doaj.org/article:4763774884534bc790cd73d9a203fb9a 2023-05-15T14:55:30+02:00 Time to reconsider the role of ribavirin in Lassa fever. Alex Paddy Salam Vincent Cheng Tansy Edwards Piero Olliaro Jonathan Sterne Peter Horby 2021-07-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0009522 https://doaj.org/article/4763774884534bc790cd73d9a203fb9a EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0009522 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0009522 https://doaj.org/article/4763774884534bc790cd73d9a203fb9a PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009522 (2021) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2021 ftdoajarticles https://doi.org/10.1371/journal.pntd.0009522 2022-12-31T08:23:47Z Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some Lassa fever patients. An urgent reevaluation of ribavirin is therefore needed. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 15 7 e0009522
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
spellingShingle Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Alex Paddy Salam
Vincent Cheng
Tansy Edwards
Piero Olliaro
Jonathan Sterne
Peter Horby
Time to reconsider the role of ribavirin in Lassa fever.
topic_facet Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
description Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some Lassa fever patients. An urgent reevaluation of ribavirin is therefore needed.
format Article in Journal/Newspaper
author Alex Paddy Salam
Vincent Cheng
Tansy Edwards
Piero Olliaro
Jonathan Sterne
Peter Horby
author_facet Alex Paddy Salam
Vincent Cheng
Tansy Edwards
Piero Olliaro
Jonathan Sterne
Peter Horby
author_sort Alex Paddy Salam
title Time to reconsider the role of ribavirin in Lassa fever.
title_short Time to reconsider the role of ribavirin in Lassa fever.
title_full Time to reconsider the role of ribavirin in Lassa fever.
title_fullStr Time to reconsider the role of ribavirin in Lassa fever.
title_full_unstemmed Time to reconsider the role of ribavirin in Lassa fever.
title_sort time to reconsider the role of ribavirin in lassa fever.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doi.org/10.1371/journal.pntd.0009522
https://doaj.org/article/4763774884534bc790cd73d9a203fb9a
geographic Arctic
geographic_facet Arctic
genre Arctic
genre_facet Arctic
op_source PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009522 (2021)
op_relation https://doi.org/10.1371/journal.pntd.0009522
https://doaj.org/toc/1935-2727
https://doaj.org/toc/1935-2735
1935-2727
1935-2735
doi:10.1371/journal.pntd.0009522
https://doaj.org/article/4763774884534bc790cd73d9a203fb9a
op_doi https://doi.org/10.1371/journal.pntd.0009522
container_title PLOS Neglected Tropical Diseases
container_volume 15
container_issue 7
container_start_page e0009522
_version_ 1766327446739615744

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