miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor
This study was designed to explore the impact of the photoperiod on the gonadal development and somatic growth of Atlantic salmon raised in recirculating aquaculture systems (RASs), with specific focus on the role that microRNA (miR)-155 plays as a regulator in the Atlantic salmon’s photoperiodic re...
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ftdoajarticles:oai:doaj.org/article:47599e1db4194b1f9c1011ccc847cf10 2023-08-20T04:05:14+02:00 miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi 2023-06-01T00:00:00Z https://doi.org/10.3390/fishes8070345 https://doaj.org/article/47599e1db4194b1f9c1011ccc847cf10 EN eng MDPI AG https://www.mdpi.com/2410-3888/8/7/345 https://doaj.org/toc/2410-3888 doi:10.3390/fishes8070345 2410-3888 https://doaj.org/article/47599e1db4194b1f9c1011ccc847cf10 Fishes, Vol 8, Iss 345, p 345 (2023) photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon Biology (General) QH301-705.5 Genetics QH426-470 article 2023 ftdoajarticles https://doi.org/10.3390/fishes8070345 2023-07-30T00:35:49Z This study was designed to explore the impact of the photoperiod on the gonadal development and somatic growth of Atlantic salmon raised in recirculating aquaculture systems (RASs), with specific focus on the role that microRNA (miR)-155 plays as a regulator in the Atlantic salmon’s photoperiodic reproduction. These salmon were reared for 5 months under six different photoperiod regimens, including two with changing photoperiods (LL–SL = 24L:0D–8L:16D and SL–LL = 8L:16D–24L:0D) and four with constant photoperiods (24L:0D, 18L:6D, 12L:12D, and 8L:16D). The longer photoperiod groups (LL–SL and 24L:0D) were ultimately associated with higher gonadosomatic index (GSI) values and an increased proportion of mature fish relative to other exposure groups, indicating that the photoperiod positively impacted the Atlantic salmon’s gonadal development in RAS environments. Hypothalamic miR-155 expression in these Atlantic salmon was also found to be influenced by the photoperiod, showing a markedly decreased expression in salmon exposed to a long photoperiod and upregulation following rearing under a short photoperiod. Functionally, miR-155 was found to suppress the expression of gonadal axis-related genes, including FSH and GnRH, through its ability to target the brain-derived neurotrophic factor (BDNF) and to thereby regulate photoperiod reproduction. Overall, these results suggested that the photoperiod could regulate gonad development in Atlantic salmon with miRNA-155 being involved in this process by targeting the BDNF. Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles Fishes 8 7 345 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon Biology (General) QH301-705.5 Genetics QH426-470 |
spellingShingle |
photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon Biology (General) QH301-705.5 Genetics QH426-470 Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor |
topic_facet |
photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon Biology (General) QH301-705.5 Genetics QH426-470 |
description |
This study was designed to explore the impact of the photoperiod on the gonadal development and somatic growth of Atlantic salmon raised in recirculating aquaculture systems (RASs), with specific focus on the role that microRNA (miR)-155 plays as a regulator in the Atlantic salmon’s photoperiodic reproduction. These salmon were reared for 5 months under six different photoperiod regimens, including two with changing photoperiods (LL–SL = 24L:0D–8L:16D and SL–LL = 8L:16D–24L:0D) and four with constant photoperiods (24L:0D, 18L:6D, 12L:12D, and 8L:16D). The longer photoperiod groups (LL–SL and 24L:0D) were ultimately associated with higher gonadosomatic index (GSI) values and an increased proportion of mature fish relative to other exposure groups, indicating that the photoperiod positively impacted the Atlantic salmon’s gonadal development in RAS environments. Hypothalamic miR-155 expression in these Atlantic salmon was also found to be influenced by the photoperiod, showing a markedly decreased expression in salmon exposed to a long photoperiod and upregulation following rearing under a short photoperiod. Functionally, miR-155 was found to suppress the expression of gonadal axis-related genes, including FSH and GnRH, through its ability to target the brain-derived neurotrophic factor (BDNF) and to thereby regulate photoperiod reproduction. Overall, these results suggested that the photoperiod could regulate gonad development in Atlantic salmon with miRNA-155 being involved in this process by targeting the BDNF. |
format |
Article in Journal/Newspaper |
author |
Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi |
author_facet |
Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi |
author_sort |
Teng Guo |
title |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor |
title_short |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor |
title_full |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor |
title_fullStr |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor |
title_full_unstemmed |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon ( Salmo salar ) by Targeting Brain-Derived Neurotrophic Factor |
title_sort |
mir-155 regulates photoperiod induced gonadal development in atlantic salmon ( salmo salar ) by targeting brain-derived neurotrophic factor |
publisher |
MDPI AG |
publishDate |
2023 |
url |
https://doi.org/10.3390/fishes8070345 https://doaj.org/article/47599e1db4194b1f9c1011ccc847cf10 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Fishes, Vol 8, Iss 345, p 345 (2023) |
op_relation |
https://www.mdpi.com/2410-3888/8/7/345 https://doaj.org/toc/2410-3888 doi:10.3390/fishes8070345 2410-3888 https://doaj.org/article/47599e1db4194b1f9c1011ccc847cf10 |
op_doi |
https://doi.org/10.3390/fishes8070345 |
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