Evaluation of ocular involvement in patients with Hansen's disease.
Hansen's disease (HD) belongs to the group of neglected diseases and can cause physical deformities and disabilities, in addition to leading to social discrimination. Ocular involvement in HD is estimated at 70-75% worldwide. About 10-50% suffer from severe ocular symptoms and loss of vision oc...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0008585 https://doaj.org/article/4758a5f8a9bd4c67868b78544ebbf56f |
id |
ftdoajarticles:oai:doaj.org/article:4758a5f8a9bd4c67868b78544ebbf56f |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:4758a5f8a9bd4c67868b78544ebbf56f 2023-05-15T15:12:21+02:00 Evaluation of ocular involvement in patients with Hansen's disease. Priscila Daiane Pavezzi Rodrigo Bueno do Prado Plinio Ângelo Boin Filho Airton Dos Santos Gon Bruna Tuma Marco Aurelio Fornazieri Fabiana de Mari Scalone Luciana Rigolin Mazoni Alves Ricardo Hirayama Montero Antonio Marcelo Barbante Casella 2020-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008585 https://doaj.org/article/4758a5f8a9bd4c67868b78544ebbf56f EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008585 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008585 https://doaj.org/article/4758a5f8a9bd4c67868b78544ebbf56f PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0008585 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008585 2022-12-31T05:51:59Z Hansen's disease (HD) belongs to the group of neglected diseases and can cause physical deformities and disabilities, in addition to leading to social discrimination. Ocular involvement in HD is estimated at 70-75% worldwide. About 10-50% suffer from severe ocular symptoms and loss of vision occurs in approximately 5% of cases. Ocular changes may persist or worsen even after patients are considered cured and it is necessary to better understand these conditions in order to determine the need for additional public policies. The objective of this study was to identify the prevalence of ocular involvement in patients with HD at two specialist referral centers for treatment of the disease. A cross-sectional study was conducted with ophthalmological evaluations of patients with HD from June 2017 to June 2018. Diagnostic ocular findings, corrected visual acuity, and refractive error were described. Findings were correlated with patients' clinical and epidemiological variables. A total of 86 patients were evaluated, with a mean age of 50.1 years, predominantly males (59.3%), and with multibacillary HD (92%). The prevalence of ophthalmologic changes was 100% and the most common were dysfunction of the Meibomian glands (89.5%) and dry eye syndrome (81.4%). Cataracts were observed in 22 patients (25.6%), but best corrected visual acuity was normal or near normal in 84 patients (97.7%) and there were no cases of bilateral blindness. Patients with some degree of physical disability had more ophthalmological alterations, involving both the ocular adnexa (p = 0.03) and the ocular globe (p = 0.04). Ocular involvement is common in patients with Hansen's disease, reinforcing the importance of ophthalmologic examination in the evaluation and follow-up of these patients. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 9 e0008585 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Priscila Daiane Pavezzi Rodrigo Bueno do Prado Plinio Ângelo Boin Filho Airton Dos Santos Gon Bruna Tuma Marco Aurelio Fornazieri Fabiana de Mari Scalone Luciana Rigolin Mazoni Alves Ricardo Hirayama Montero Antonio Marcelo Barbante Casella Evaluation of ocular involvement in patients with Hansen's disease. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Hansen's disease (HD) belongs to the group of neglected diseases and can cause physical deformities and disabilities, in addition to leading to social discrimination. Ocular involvement in HD is estimated at 70-75% worldwide. About 10-50% suffer from severe ocular symptoms and loss of vision occurs in approximately 5% of cases. Ocular changes may persist or worsen even after patients are considered cured and it is necessary to better understand these conditions in order to determine the need for additional public policies. The objective of this study was to identify the prevalence of ocular involvement in patients with HD at two specialist referral centers for treatment of the disease. A cross-sectional study was conducted with ophthalmological evaluations of patients with HD from June 2017 to June 2018. Diagnostic ocular findings, corrected visual acuity, and refractive error were described. Findings were correlated with patients' clinical and epidemiological variables. A total of 86 patients were evaluated, with a mean age of 50.1 years, predominantly males (59.3%), and with multibacillary HD (92%). The prevalence of ophthalmologic changes was 100% and the most common were dysfunction of the Meibomian glands (89.5%) and dry eye syndrome (81.4%). Cataracts were observed in 22 patients (25.6%), but best corrected visual acuity was normal or near normal in 84 patients (97.7%) and there were no cases of bilateral blindness. Patients with some degree of physical disability had more ophthalmological alterations, involving both the ocular adnexa (p = 0.03) and the ocular globe (p = 0.04). Ocular involvement is common in patients with Hansen's disease, reinforcing the importance of ophthalmologic examination in the evaluation and follow-up of these patients. |
format |
Article in Journal/Newspaper |
author |
Priscila Daiane Pavezzi Rodrigo Bueno do Prado Plinio Ângelo Boin Filho Airton Dos Santos Gon Bruna Tuma Marco Aurelio Fornazieri Fabiana de Mari Scalone Luciana Rigolin Mazoni Alves Ricardo Hirayama Montero Antonio Marcelo Barbante Casella |
author_facet |
Priscila Daiane Pavezzi Rodrigo Bueno do Prado Plinio Ângelo Boin Filho Airton Dos Santos Gon Bruna Tuma Marco Aurelio Fornazieri Fabiana de Mari Scalone Luciana Rigolin Mazoni Alves Ricardo Hirayama Montero Antonio Marcelo Barbante Casella |
author_sort |
Priscila Daiane Pavezzi |
title |
Evaluation of ocular involvement in patients with Hansen's disease. |
title_short |
Evaluation of ocular involvement in patients with Hansen's disease. |
title_full |
Evaluation of ocular involvement in patients with Hansen's disease. |
title_fullStr |
Evaluation of ocular involvement in patients with Hansen's disease. |
title_full_unstemmed |
Evaluation of ocular involvement in patients with Hansen's disease. |
title_sort |
evaluation of ocular involvement in patients with hansen's disease. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008585 https://doaj.org/article/4758a5f8a9bd4c67868b78544ebbf56f |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0008585 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008585 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008585 https://doaj.org/article/4758a5f8a9bd4c67868b78544ebbf56f |
op_doi |
https://doi.org/10.1371/journal.pntd.0008585 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
14 |
container_issue |
9 |
container_start_page |
e0008585 |
_version_ |
1766343044732289024 |