Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013
ABSTRACT Objective To characterize cancer clinical trials in Latin America and the Caribbean (LAC), with a focus on registration and enrollment trends. Methods Data were collected from 1 285 active cancer clinical trials registered up until 31 May 2014 in the World Health Organization’s Internationa...
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ftdoajarticles:oai:doaj.org/article:45f336c8ec1243b787a544130f34629b 2023-05-15T15:10:29+02:00 Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013 Bridget Lee Luis G. Cuervo Pablo Rodríguez-Feria Silvana Luciani https://doaj.org/article/45f336c8ec1243b787a544130f34629b EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016000200115&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/45f336c8ec1243b787a544130f34629b Revista Panamericana de Salud Pública, Vol 39, Iss 2, Pp 115-121 Neoplasms clinical trial health research policy health research evaluation Caribbean region Latin America Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article ftdoajarticles 2022-12-31T05:34:30Z ABSTRACT Objective To characterize cancer clinical trials in Latin America and the Caribbean (LAC), with a focus on registration and enrollment trends. Methods Data were collected from 1 285 active cancer clinical trials registered up until 31 May 2014 in the World Health Organization’s International Clinical Trial Registry Platform (ICTRP). The trials were categorized by six characteristics of the continuum of cancer control and care: 1) control and planning, 2) prevention, 3) detection and screening, 4) diagnosis, 5) treatment, and 6) survivorship and palliative care. The search strategy protocol included the use of optimized keywords combined with the names of the 43 countries selected for a descriptive analysis. Results A total of 973 registered and 972 enrolled cancer clinical trials between January 2007 and December 2013 were identified. Trends of growth were observed for both registration and enrollment of cancer treatment clinical trials; for other types of cancer clinical trials, trends for registration and enrollment varied in direction. Conclusions Growth trends in the registration of cancer treatment clinical trials indicate incremental adherence to cancer research reporting and improvements in cancer research transparency. The higher proportion of cancer treatment trials versus other types of cancer clinical trials indicates an imbalance in cancer research in the LAC region and suggests the need for more funding and incentives for other areas of research in order to achieve a more comprehensive approach to gaining knowledge on cancer issues. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English Spanish Portuguese |
topic |
Neoplasms clinical trial health research policy health research evaluation Caribbean region Latin America Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Neoplasms clinical trial health research policy health research evaluation Caribbean region Latin America Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Bridget Lee Luis G. Cuervo Pablo Rodríguez-Feria Silvana Luciani Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013 |
topic_facet |
Neoplasms clinical trial health research policy health research evaluation Caribbean region Latin America Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
ABSTRACT Objective To characterize cancer clinical trials in Latin America and the Caribbean (LAC), with a focus on registration and enrollment trends. Methods Data were collected from 1 285 active cancer clinical trials registered up until 31 May 2014 in the World Health Organization’s International Clinical Trial Registry Platform (ICTRP). The trials were categorized by six characteristics of the continuum of cancer control and care: 1) control and planning, 2) prevention, 3) detection and screening, 4) diagnosis, 5) treatment, and 6) survivorship and palliative care. The search strategy protocol included the use of optimized keywords combined with the names of the 43 countries selected for a descriptive analysis. Results A total of 973 registered and 972 enrolled cancer clinical trials between January 2007 and December 2013 were identified. Trends of growth were observed for both registration and enrollment of cancer treatment clinical trials; for other types of cancer clinical trials, trends for registration and enrollment varied in direction. Conclusions Growth trends in the registration of cancer treatment clinical trials indicate incremental adherence to cancer research reporting and improvements in cancer research transparency. The higher proportion of cancer treatment trials versus other types of cancer clinical trials indicates an imbalance in cancer research in the LAC region and suggests the need for more funding and incentives for other areas of research in order to achieve a more comprehensive approach to gaining knowledge on cancer issues. |
format |
Article in Journal/Newspaper |
author |
Bridget Lee Luis G. Cuervo Pablo Rodríguez-Feria Silvana Luciani |
author_facet |
Bridget Lee Luis G. Cuervo Pablo Rodríguez-Feria Silvana Luciani |
author_sort |
Bridget Lee |
title |
Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013 |
title_short |
Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013 |
title_full |
Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013 |
title_fullStr |
Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013 |
title_full_unstemmed |
Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013 |
title_sort |
analysis of registered cancer clinical trials in latin america and the caribbean, 2007-2013 |
publisher |
Pan American Health Organization |
url |
https://doaj.org/article/45f336c8ec1243b787a544130f34629b |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 39, Iss 2, Pp 115-121 |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016000200115&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/45f336c8ec1243b787a544130f34629b |
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1766341510812401664 |