Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats
The effect of an 8 hour-period of water deprivation on fluid and electrolyte renal excretion was investigated in male Wistar rats infected with the strain São Felipe (12SF) of Trypanosoma cruzi, in comparison with age and sex matched non-infected controls. The median percent reductions in the urinar...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1995
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ftdoajarticles:oai:doaj.org/article:45b876ed343443aa8cc54b607daaeb4e 2023-05-15T15:16:16+02:00 Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats T.T. Rosa L.F. Junqueira Junior F.J.C. Mangia J.P.R. Veiga F.V. Pádua 1995-03-01T00:00:00Z https://doaj.org/article/45b876ed343443aa8cc54b607daaeb4e EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000100002 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/45b876ed343443aa8cc54b607daaeb4e Revista da Sociedade Brasileira de Medicina Tropical, Vol 28, Iss 1, Pp 7-11 (1995) Hidropenia Fluxo urinário Sódio e potássio urinários Taxa de filtração glomerular Infecção murina por T. cruzi Water deprivation Urinary flow Urinary sodium and potassium Glomerular filtration rate T. cruzi-infected rat Arctic medicine. Tropical medicine RC955-962 article 1995 ftdoajarticles 2022-12-30T23:17:53Z The effect of an 8 hour-period of water deprivation on fluid and electrolyte renal excretion was investigated in male Wistar rats infected with the strain São Felipe (12SF) of Trypanosoma cruzi, in comparison with age and sex matched non-infected controls. The median percent reductions in the urinary flow (-40% v -63%) and excretion ofsodium (-57% v-79%) were smaller in chagasic than in control rats, respectively. So, chagasic rats excreted more than controls. On the other hand, the median percent decrement in the clearance of creatinine was higher in chagasic (-51%) than in controls (-39%). Thus, chagasic rats showed some disturbed renal hydroelectrolytic responses to water deprivation, expressed by smaller conservation, or higher excretion of water and sodium in association with smaller glomerularfiltration rate. This fact denoted an elevation in the fractional excretion of sodium and water. O efeito de 8 horas do jejum hídrico sobre a excreção renal de sódio e água foi investigado em ratos Wistar machos infectados com a cepa São Felipe (12SF) do T. cruzi e comparados com ratos controles, de mesma idade e sexo. Durante a hidropenia, a mediana da redução no fluxo urinário (-40% v -63%) e a excreção urinária de sódio (-57% v -79%) foram menores nos chagásicos do que nos controles, respectivamente. Assim os ratos chagásicos excretaram mais do que os controles. Por outro lado, a mediana do decréscimo percentual na depuração de creaünina foi maior nos chagásicos (-51%) do que nos controles' (-39%,). Portanto, os ratos chagásicos mostraram alteração na resposta excretória hidroeletrolítica renal expressa por menor conservação de água e sódio em associação à menor taxa de filtração. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Hidropenia Fluxo urinário Sódio e potássio urinários Taxa de filtração glomerular Infecção murina por T. cruzi Water deprivation Urinary flow Urinary sodium and potassium Glomerular filtration rate T. cruzi-infected rat Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Hidropenia Fluxo urinário Sódio e potássio urinários Taxa de filtração glomerular Infecção murina por T. cruzi Water deprivation Urinary flow Urinary sodium and potassium Glomerular filtration rate T. cruzi-infected rat Arctic medicine. Tropical medicine RC955-962 T.T. Rosa L.F. Junqueira Junior F.J.C. Mangia J.P.R. Veiga F.V. Pádua Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats |
topic_facet |
Hidropenia Fluxo urinário Sódio e potássio urinários Taxa de filtração glomerular Infecção murina por T. cruzi Water deprivation Urinary flow Urinary sodium and potassium Glomerular filtration rate T. cruzi-infected rat Arctic medicine. Tropical medicine RC955-962 |
description |
The effect of an 8 hour-period of water deprivation on fluid and electrolyte renal excretion was investigated in male Wistar rats infected with the strain São Felipe (12SF) of Trypanosoma cruzi, in comparison with age and sex matched non-infected controls. The median percent reductions in the urinary flow (-40% v -63%) and excretion ofsodium (-57% v-79%) were smaller in chagasic than in control rats, respectively. So, chagasic rats excreted more than controls. On the other hand, the median percent decrement in the clearance of creatinine was higher in chagasic (-51%) than in controls (-39%). Thus, chagasic rats showed some disturbed renal hydroelectrolytic responses to water deprivation, expressed by smaller conservation, or higher excretion of water and sodium in association with smaller glomerularfiltration rate. This fact denoted an elevation in the fractional excretion of sodium and water. O efeito de 8 horas do jejum hídrico sobre a excreção renal de sódio e água foi investigado em ratos Wistar machos infectados com a cepa São Felipe (12SF) do T. cruzi e comparados com ratos controles, de mesma idade e sexo. Durante a hidropenia, a mediana da redução no fluxo urinário (-40% v -63%) e a excreção urinária de sódio (-57% v -79%) foram menores nos chagásicos do que nos controles, respectivamente. Assim os ratos chagásicos excretaram mais do que os controles. Por outro lado, a mediana do decréscimo percentual na depuração de creaünina foi maior nos chagásicos (-51%) do que nos controles' (-39%,). Portanto, os ratos chagásicos mostraram alteração na resposta excretória hidroeletrolítica renal expressa por menor conservação de água e sódio em associação à menor taxa de filtração. |
format |
Article in Journal/Newspaper |
author |
T.T. Rosa L.F. Junqueira Junior F.J.C. Mangia J.P.R. Veiga F.V. Pádua |
author_facet |
T.T. Rosa L.F. Junqueira Junior F.J.C. Mangia J.P.R. Veiga F.V. Pádua |
author_sort |
T.T. Rosa |
title |
Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats |
title_short |
Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats |
title_full |
Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats |
title_fullStr |
Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats |
title_full_unstemmed |
Effects of water deprivation on renal hydroelectrolytic excretion in chronically Trypanosoma cruzi-infected rats |
title_sort |
effects of water deprivation on renal hydroelectrolytic excretion in chronically trypanosoma cruzi-infected rats |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
1995 |
url |
https://doaj.org/article/45b876ed343443aa8cc54b607daaeb4e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 28, Iss 1, Pp 7-11 (1995) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000100002 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/45b876ed343443aa8cc54b607daaeb4e |
_version_ |
1766346549771632640 |