Diagnóstico diferencial de virus hepatótropos y no hepatótropos en pacientes atendidos en el Laboratorio Regional de Referencia Virológica. Maracaibo-Venezuela, año 2007

• Main Authors: Costa-León Luciana, Monsalve-Castillo Francisca, Callejas-Valero Diana, Porto-Espinoza Leticia, Estévez, Jesús, Castellanos María Elena, Mindiola Raimy
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2010
• Subjects: Citomegalovirus; Virus Epstein Barr; hepatitis; Cytomegalovirus; Epstein Barr Virus; Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Referencia
• Online Access: https://doaj.org/article/44c7a2a39d934b8cb83416ff4ee043cd

Abstract: Viral hepatitis is a public health problem worldwide, caused by different etiologic agents, such as hepatitis A, B, C, D, E, F or G. However, cases have been reported related to liver disease caused by hepatotropic viruses, such as cytomegalovirus (CMV) and Epstein Barr Virus (EBV). The aim of this study was to establish the differential diagnosis of hepatotropic and non-hepatotropic viruses in patients with symptoms and signs suggestive of liver infection in the city of Maracaibo, Venezuela, 2007. 268 blood samples were collected from patients at different health centers in the city of Maracaibo, who recurred to the Regional Viral Reference Laboratory. The presence of IgM antibodies to hepatitis A virus (HAV), B (HBV), C (HCV), CMV and EBV was detected by ELISA. The results indicate a high incidence of HAV 118/268 (44.03%), followed by HBV 5/268 (1.86%) and the absence of HCV. For non-hepatotropic viruses, 4.48% (12/268) were positive for EBV and 9.7% (26/268) for CMV. For the above-mentioned viruses, 39.92% (107/268) are considered negative. This study suggests that CMV and EBV viruses are often involved with liver damage and should be considered as possible etiologic agents for any case of hepatitis. Key words: Cytomegalovirus, Epstein Barr Virus, hepatitis. Resumen: La hepatitis viral representa un problema de salud pública a escala mundial, causada por diferentes agentes etiológico como el virus de la hepatitis A, B, C, D, E, F o G. Sin embargo, se han reportado casos relacionados con la enfermedad hepática causados por virus no hepatótropos como el Citomegalovirus (CMV) y el Virus Epstein Barr (VEB). El objetivo del presente estudio fue establecer el diagnóstico diferencial de virus hepatótropos y no hepatótropos en pacientes con síntomas y signos sugestivo de infección hepática, de la ciudad de Maracaibo-Venezuela. Año 2007. Se recolectaron 268 muestras de sangre de pacientes procedente de diferentes centros de salud de la ciudad de Maracaibo, que acudieron al Laboratorio regional de Referencias ...