Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways
Abstract Vector control is a task previously relegated to products that (a) kill the mosquitoes directly at different stages (insecticides, larvicides, baited traps), or (b) avoid/reduce human-mosquito contact (bed nets, repellents, house screening), thereby reducing transmission. The potential comm...
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ftdoajarticles:oai:doaj.org/article:44c0a15e603e4676b2034ad6b65966dc 2023-05-15T15:05:10+02:00 Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways Carlos Chaccour N. Regina Rabinovich 2017-04-01T00:00:00Z https://doi.org/10.1186/s12936-017-1803-2 https://doaj.org/article/44c0a15e603e4676b2034ad6b65966dc EN eng BMC http://link.springer.com/article/10.1186/s12936-017-1803-2 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-017-1803-2 1475-2875 https://doaj.org/article/44c0a15e603e4676b2034ad6b65966dc Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017) Ivermectin Endectocide Regulatory pathway Malaria Policy Anopheles Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2017 ftdoajarticles https://doi.org/10.1186/s12936-017-1803-2 2022-12-31T14:37:39Z Abstract Vector control is a task previously relegated to products that (a) kill the mosquitoes directly at different stages (insecticides, larvicides, baited traps), or (b) avoid/reduce human-mosquito contact (bed nets, repellents, house screening), thereby reducing transmission. The potential community-based administration of the endectocide ivermectin with the intent to kill mosquitoes that bite humans, and thus reduce malaria transmission, offers a novel approach using a well-known drug, but additional steps are required to address technical, regulatory and policy gaps. The proposed community administration of this drug presents dual novel paradigms; first, indirect impact on the community rather than on individuals, and second, the use of a drug for vector control. In this paper, the main questions related to the regulatory and policy pathways for such an application are identified. Succinct answers are proposed for how the efficacy, safety, acceptability, cost-effectiveness and programmatic suitability could result in regulatory approval and ultimately policy recommendations on the use of ivermectin as a complementary vector control tool. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 16 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Ivermectin Endectocide Regulatory pathway Malaria Policy Anopheles Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Ivermectin Endectocide Regulatory pathway Malaria Policy Anopheles Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Carlos Chaccour N. Regina Rabinovich Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways |
topic_facet |
Ivermectin Endectocide Regulatory pathway Malaria Policy Anopheles Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Vector control is a task previously relegated to products that (a) kill the mosquitoes directly at different stages (insecticides, larvicides, baited traps), or (b) avoid/reduce human-mosquito contact (bed nets, repellents, house screening), thereby reducing transmission. The potential community-based administration of the endectocide ivermectin with the intent to kill mosquitoes that bite humans, and thus reduce malaria transmission, offers a novel approach using a well-known drug, but additional steps are required to address technical, regulatory and policy gaps. The proposed community administration of this drug presents dual novel paradigms; first, indirect impact on the community rather than on individuals, and second, the use of a drug for vector control. In this paper, the main questions related to the regulatory and policy pathways for such an application are identified. Succinct answers are proposed for how the efficacy, safety, acceptability, cost-effectiveness and programmatic suitability could result in regulatory approval and ultimately policy recommendations on the use of ivermectin as a complementary vector control tool. |
format |
Article in Journal/Newspaper |
author |
Carlos Chaccour N. Regina Rabinovich |
author_facet |
Carlos Chaccour N. Regina Rabinovich |
author_sort |
Carlos Chaccour |
title |
Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways |
title_short |
Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways |
title_full |
Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways |
title_fullStr |
Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways |
title_full_unstemmed |
Ivermectin to reduce malaria transmission III. Considerations regarding regulatory and policy pathways |
title_sort |
ivermectin to reduce malaria transmission iii. considerations regarding regulatory and policy pathways |
publisher |
BMC |
publishDate |
2017 |
url |
https://doi.org/10.1186/s12936-017-1803-2 https://doaj.org/article/44c0a15e603e4676b2034ad6b65966dc |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017) |
op_relation |
http://link.springer.com/article/10.1186/s12936-017-1803-2 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-017-1803-2 1475-2875 https://doaj.org/article/44c0a15e603e4676b2034ad6b65966dc |
op_doi |
https://doi.org/10.1186/s12936-017-1803-2 |
container_title |
Malaria Journal |
container_volume |
16 |
container_issue |
1 |
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1766336915243532288 |