Malaria in Southern Venezuela: The hottest hotspot in Latin America.
Malaria elimination in Latin America is becoming an elusive goal. Malaria cases reached a historical ~1 million in 2017 and 2018, with Venezuela contributing 53% and 51% of those cases, respectively. Historically, malaria incidence in southern Venezuela has accounted for most of the country's t...
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Online Access: | https://doi.org/10.1371/journal.pntd.0008211 https://doaj.org/article/449467b4cb9f4eebbe8f8a44fb3d7ded |
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ftdoajarticles:oai:doaj.org/article:449467b4cb9f4eebbe8f8a44fb3d7ded 2023-05-15T15:08:31+02:00 Malaria in Southern Venezuela: The hottest hotspot in Latin America. Maria Eugenia Grillet Jorge E Moreno Juan V Hernández-Villena Maria F Vincenti-González Oscar Noya Adriana Tami Alberto Paniz-Mondolfi Martin Llewellyn Rachel Lowe Ananías A Escalante Jan E Conn 2021-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008211 https://doaj.org/article/449467b4cb9f4eebbe8f8a44fb3d7ded EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008211 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008211 https://doaj.org/article/449467b4cb9f4eebbe8f8a44fb3d7ded PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008211 (2021) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2021 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008211 2022-12-31T05:59:59Z Malaria elimination in Latin America is becoming an elusive goal. Malaria cases reached a historical ~1 million in 2017 and 2018, with Venezuela contributing 53% and 51% of those cases, respectively. Historically, malaria incidence in southern Venezuela has accounted for most of the country's total number of cases. The efficient deployment of disease prevention measures and prediction of disease spread to new regions requires an in-depth understanding of spatial heterogeneity on malaria transmission dynamics. Herein, we characterized the spatial epidemiology of malaria in southern Venezuela from 2007 through 2017 and described the extent to which malaria distribution has changed country-wide over the recent years. We found that disease transmission was focal and more prevalent in the southeast region of southern Venezuela where two persistent hotspots of Plasmodium vivax (76%) and P. falciparum (18%) accounted for ~60% of the total number of cases. Such hotspots are linked to deforestation as a consequence of illegal gold mining activities. Incidence has increased nearly tenfold over the last decade, showing an explosive epidemic growth due to a significant lack of disease control programs. Our findings highlight the importance of spatially oriented interventions to contain the ongoing malaria epidemic in Venezuela. This work also provides baseline epidemiological data to assess cross-border malaria dynamics and advocates for innovative control efforts in the Latin American region. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 15 1 e0008211 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Maria Eugenia Grillet Jorge E Moreno Juan V Hernández-Villena Maria F Vincenti-González Oscar Noya Adriana Tami Alberto Paniz-Mondolfi Martin Llewellyn Rachel Lowe Ananías A Escalante Jan E Conn Malaria in Southern Venezuela: The hottest hotspot in Latin America. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Malaria elimination in Latin America is becoming an elusive goal. Malaria cases reached a historical ~1 million in 2017 and 2018, with Venezuela contributing 53% and 51% of those cases, respectively. Historically, malaria incidence in southern Venezuela has accounted for most of the country's total number of cases. The efficient deployment of disease prevention measures and prediction of disease spread to new regions requires an in-depth understanding of spatial heterogeneity on malaria transmission dynamics. Herein, we characterized the spatial epidemiology of malaria in southern Venezuela from 2007 through 2017 and described the extent to which malaria distribution has changed country-wide over the recent years. We found that disease transmission was focal and more prevalent in the southeast region of southern Venezuela where two persistent hotspots of Plasmodium vivax (76%) and P. falciparum (18%) accounted for ~60% of the total number of cases. Such hotspots are linked to deforestation as a consequence of illegal gold mining activities. Incidence has increased nearly tenfold over the last decade, showing an explosive epidemic growth due to a significant lack of disease control programs. Our findings highlight the importance of spatially oriented interventions to contain the ongoing malaria epidemic in Venezuela. This work also provides baseline epidemiological data to assess cross-border malaria dynamics and advocates for innovative control efforts in the Latin American region. |
format |
Article in Journal/Newspaper |
author |
Maria Eugenia Grillet Jorge E Moreno Juan V Hernández-Villena Maria F Vincenti-González Oscar Noya Adriana Tami Alberto Paniz-Mondolfi Martin Llewellyn Rachel Lowe Ananías A Escalante Jan E Conn |
author_facet |
Maria Eugenia Grillet Jorge E Moreno Juan V Hernández-Villena Maria F Vincenti-González Oscar Noya Adriana Tami Alberto Paniz-Mondolfi Martin Llewellyn Rachel Lowe Ananías A Escalante Jan E Conn |
author_sort |
Maria Eugenia Grillet |
title |
Malaria in Southern Venezuela: The hottest hotspot in Latin America. |
title_short |
Malaria in Southern Venezuela: The hottest hotspot in Latin America. |
title_full |
Malaria in Southern Venezuela: The hottest hotspot in Latin America. |
title_fullStr |
Malaria in Southern Venezuela: The hottest hotspot in Latin America. |
title_full_unstemmed |
Malaria in Southern Venezuela: The hottest hotspot in Latin America. |
title_sort |
malaria in southern venezuela: the hottest hotspot in latin america. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doi.org/10.1371/journal.pntd.0008211 https://doaj.org/article/449467b4cb9f4eebbe8f8a44fb3d7ded |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008211 (2021) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008211 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008211 https://doaj.org/article/449467b4cb9f4eebbe8f8a44fb3d7ded |
op_doi |
https://doi.org/10.1371/journal.pntd.0008211 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
15 |
container_issue |
1 |
container_start_page |
e0008211 |
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1766339873494532096 |