Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk.
BACKGROUND:Few studies of dengue have shown group-level associations between demographic, socioeconomic, or geographic characteristics and the spatial distribution of dengue within small urban areas. This study aimed to examine whether specific characteristics of an urban slum community were associa...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0003937 https://doaj.org/article/42a3e2a4953f4954b1e5d734f49f5066 |
id |
ftdoajarticles:oai:doaj.org/article:42a3e2a4953f4954b1e5d734f49f5066 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:42a3e2a4953f4954b1e5d734f49f5066 2023-05-15T15:15:42+02:00 Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk. Mariana Kikuti Geraldo M Cunha Igor A D Paploski Amelia M Kasper Monaise M O Silva Aline S Tavares Jaqueline S Cruz Tássia L Queiroz Moreno S Rodrigues Perla M Santana Helena C A V Lima Juan Calcagno Daniele Takahashi André H O Gonçalves Josélio M G Araújo Kristine Gauthier Maria A Diuk-Wasser Uriel Kitron Albert I Ko Mitermayer G Reis Guilherme S Ribeiro 2015-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003937 https://doaj.org/article/42a3e2a4953f4954b1e5d734f49f5066 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4510880?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003937 https://doaj.org/article/42a3e2a4953f4954b1e5d734f49f5066 PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003937 (2015) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2015 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003937 2022-12-30T22:25:06Z BACKGROUND:Few studies of dengue have shown group-level associations between demographic, socioeconomic, or geographic characteristics and the spatial distribution of dengue within small urban areas. This study aimed to examine whether specific characteristics of an urban slum community were associated with the risk of dengue disease. METHODOLOGY/PRINCIPAL FINDINGS:From 01/2009 to 12/2010, we conducted enhanced, community-based surveillance in the only public emergency unit in a slum in Salvador, Brazil to identify acute febrile illness (AFI) patients with laboratory evidence of dengue infection. Patient households were geocoded within census tracts (CTs). Demographic, socioeconomic, and geographical data were obtained from the 2010 national census. Associations between CTs characteristics and the spatial risk of both dengue and non-dengue AFI were assessed by Poisson log-normal and conditional auto-regressive models (CAR). We identified 651 (22.0%) dengue cases among 2,962 AFI patients. Estimated risk of symptomatic dengue was 21.3 and 70.2 cases per 10,000 inhabitants in 2009 and 2010, respectively. All the four dengue serotypes were identified, but DENV2 predominated (DENV1: 8.1%; DENV2: 90.7%; DENV3: 0.4%; DENV4: 0.8%). Multivariable CAR regression analysis showed increased dengue risk in CTs with poorer inhabitants (RR: 1.02 for each percent increase in the frequency of families earning ≤1 times the minimum wage; 95% CI: 1.01-1.04), and decreased risk in CTs located farther from the health unit (RR: 0.87 for each 100 meter increase; 95% CI: 0.80-0.94). The same CTs characteristics were also associated with non-dengue AFI risk. CONCLUSIONS/SIGNIFICANCE:This study highlights the large burden of symptomatic dengue on individuals living in urban slums in Brazil. Lower neighborhood socioeconomic status was independently associated with increased risk of dengue, indicating that within slum communities with high levels of absolute poverty, factors associated with the social gradient influence dengue transmission. ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 9 7 e0003937 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Mariana Kikuti Geraldo M Cunha Igor A D Paploski Amelia M Kasper Monaise M O Silva Aline S Tavares Jaqueline S Cruz Tássia L Queiroz Moreno S Rodrigues Perla M Santana Helena C A V Lima Juan Calcagno Daniele Takahashi André H O Gonçalves Josélio M G Araújo Kristine Gauthier Maria A Diuk-Wasser Uriel Kitron Albert I Ko Mitermayer G Reis Guilherme S Ribeiro Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Few studies of dengue have shown group-level associations between demographic, socioeconomic, or geographic characteristics and the spatial distribution of dengue within small urban areas. This study aimed to examine whether specific characteristics of an urban slum community were associated with the risk of dengue disease. METHODOLOGY/PRINCIPAL FINDINGS:From 01/2009 to 12/2010, we conducted enhanced, community-based surveillance in the only public emergency unit in a slum in Salvador, Brazil to identify acute febrile illness (AFI) patients with laboratory evidence of dengue infection. Patient households were geocoded within census tracts (CTs). Demographic, socioeconomic, and geographical data were obtained from the 2010 national census. Associations between CTs characteristics and the spatial risk of both dengue and non-dengue AFI were assessed by Poisson log-normal and conditional auto-regressive models (CAR). We identified 651 (22.0%) dengue cases among 2,962 AFI patients. Estimated risk of symptomatic dengue was 21.3 and 70.2 cases per 10,000 inhabitants in 2009 and 2010, respectively. All the four dengue serotypes were identified, but DENV2 predominated (DENV1: 8.1%; DENV2: 90.7%; DENV3: 0.4%; DENV4: 0.8%). Multivariable CAR regression analysis showed increased dengue risk in CTs with poorer inhabitants (RR: 1.02 for each percent increase in the frequency of families earning ≤1 times the minimum wage; 95% CI: 1.01-1.04), and decreased risk in CTs located farther from the health unit (RR: 0.87 for each 100 meter increase; 95% CI: 0.80-0.94). The same CTs characteristics were also associated with non-dengue AFI risk. CONCLUSIONS/SIGNIFICANCE:This study highlights the large burden of symptomatic dengue on individuals living in urban slums in Brazil. Lower neighborhood socioeconomic status was independently associated with increased risk of dengue, indicating that within slum communities with high levels of absolute poverty, factors associated with the social gradient influence dengue transmission. ... |
format |
Article in Journal/Newspaper |
author |
Mariana Kikuti Geraldo M Cunha Igor A D Paploski Amelia M Kasper Monaise M O Silva Aline S Tavares Jaqueline S Cruz Tássia L Queiroz Moreno S Rodrigues Perla M Santana Helena C A V Lima Juan Calcagno Daniele Takahashi André H O Gonçalves Josélio M G Araújo Kristine Gauthier Maria A Diuk-Wasser Uriel Kitron Albert I Ko Mitermayer G Reis Guilherme S Ribeiro |
author_facet |
Mariana Kikuti Geraldo M Cunha Igor A D Paploski Amelia M Kasper Monaise M O Silva Aline S Tavares Jaqueline S Cruz Tássia L Queiroz Moreno S Rodrigues Perla M Santana Helena C A V Lima Juan Calcagno Daniele Takahashi André H O Gonçalves Josélio M G Araújo Kristine Gauthier Maria A Diuk-Wasser Uriel Kitron Albert I Ko Mitermayer G Reis Guilherme S Ribeiro |
author_sort |
Mariana Kikuti |
title |
Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk. |
title_short |
Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk. |
title_full |
Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk. |
title_fullStr |
Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk. |
title_full_unstemmed |
Spatial Distribution of Dengue in a Brazilian Urban Slum Setting: Role of Socioeconomic Gradient in Disease Risk. |
title_sort |
spatial distribution of dengue in a brazilian urban slum setting: role of socioeconomic gradient in disease risk. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2015 |
url |
https://doi.org/10.1371/journal.pntd.0003937 https://doaj.org/article/42a3e2a4953f4954b1e5d734f49f5066 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003937 (2015) |
op_relation |
http://europepmc.org/articles/PMC4510880?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003937 https://doaj.org/article/42a3e2a4953f4954b1e5d734f49f5066 |
op_doi |
https://doi.org/10.1371/journal.pntd.0003937 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
9 |
container_issue |
7 |
container_start_page |
e0003937 |
_version_ |
1766346050585493504 |