Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study
Dengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. This was a retrospective stud...
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ftdoajarticles:oai:doaj.org/article:420695a8a64640aa9e85b51213ee7262 2023-05-15T15:07:30+02:00 Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study Ramakrishna Pai Jakribettu Rekha Boloor Andrew Thaliath Sharanya Yesudasan George Thomas George Manoj Ponadka Rai Umran Rafique Sheikh Kadke Shreedhara Avabratha Manjeshwar Shrinath Baliga 2015-01-01T00:00:00Z https://doi.org/10.1155/2015/647162 https://doaj.org/article/420695a8a64640aa9e85b51213ee7262 EN eng Hindawi Limited http://dx.doi.org/10.1155/2015/647162 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2015/647162 https://doaj.org/article/420695a8a64640aa9e85b51213ee7262 Journal of Tropical Medicine, Vol 2015 (2015) Arctic medicine. Tropical medicine RC955-962 article 2015 ftdoajarticles https://doi.org/10.1155/2015/647162 2022-12-31T10:54:59Z Dengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. This was a retrospective study conducted in a tertiary care hospital in Coastal Karnataka, South India, to know the correlation between the clinical presentation and haematological parameters in the paediatric cases presented with dengue symptoms. A total of 163 paediatric cases who presented fever and dengue-like illness were included in the study. Of which, 69 were confirmed dengue patients. Critical analysis showed that there was a significant difference in the haematological parameters like total leucocyte count, percent differential leucocyte count, and platelets count, in the erythrocyte sedimentation rate (P<0.05 to 0.0001). Additionally, when compared to nondengue patients, even the liver function and renal function parameters were significantly deranged (P<0.05 to 0.0001). Stratification based on NS1, IgG, and IgM showed significant alterations in the haematological, hepatic, and renal parameters. With respect to the treatment a small percentage of patients, that is, 8% (4 patients), required platelet transfusion as their counts went below 20,000/μL. Two patients succumbed to their illness while three required ICU stay. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2015 1 7 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Ramakrishna Pai Jakribettu Rekha Boloor Andrew Thaliath Sharanya Yesudasan George Thomas George Manoj Ponadka Rai Umran Rafique Sheikh Kadke Shreedhara Avabratha Manjeshwar Shrinath Baliga Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Dengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. This was a retrospective study conducted in a tertiary care hospital in Coastal Karnataka, South India, to know the correlation between the clinical presentation and haematological parameters in the paediatric cases presented with dengue symptoms. A total of 163 paediatric cases who presented fever and dengue-like illness were included in the study. Of which, 69 were confirmed dengue patients. Critical analysis showed that there was a significant difference in the haematological parameters like total leucocyte count, percent differential leucocyte count, and platelets count, in the erythrocyte sedimentation rate (P<0.05 to 0.0001). Additionally, when compared to nondengue patients, even the liver function and renal function parameters were significantly deranged (P<0.05 to 0.0001). Stratification based on NS1, IgG, and IgM showed significant alterations in the haematological, hepatic, and renal parameters. With respect to the treatment a small percentage of patients, that is, 8% (4 patients), required platelet transfusion as their counts went below 20,000/μL. Two patients succumbed to their illness while three required ICU stay. |
format |
Article in Journal/Newspaper |
author |
Ramakrishna Pai Jakribettu Rekha Boloor Andrew Thaliath Sharanya Yesudasan George Thomas George Manoj Ponadka Rai Umran Rafique Sheikh Kadke Shreedhara Avabratha Manjeshwar Shrinath Baliga |
author_facet |
Ramakrishna Pai Jakribettu Rekha Boloor Andrew Thaliath Sharanya Yesudasan George Thomas George Manoj Ponadka Rai Umran Rafique Sheikh Kadke Shreedhara Avabratha Manjeshwar Shrinath Baliga |
author_sort |
Ramakrishna Pai Jakribettu |
title |
Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
title_short |
Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
title_full |
Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
title_fullStr |
Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
title_full_unstemmed |
Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
title_sort |
correlation of clinicohaematological parameters in paediatric dengue: a retrospective study |
publisher |
Hindawi Limited |
publishDate |
2015 |
url |
https://doi.org/10.1155/2015/647162 https://doaj.org/article/420695a8a64640aa9e85b51213ee7262 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2015 (2015) |
op_relation |
http://dx.doi.org/10.1155/2015/647162 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2015/647162 https://doaj.org/article/420695a8a64640aa9e85b51213ee7262 |
op_doi |
https://doi.org/10.1155/2015/647162 |
container_title |
Journal of Tropical Medicine |
container_volume |
2015 |
container_start_page |
1 |
op_container_end_page |
7 |
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1766338990338736128 |