Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study
INTRODUCTION: It is known that the hepatitis B (HB) vaccine is effective, but it is alarming that sudden drops of antibody levels may coincide with the onset of adolescence. METHODS: Antibody levels against HB vaccine surface antigen (anti-HBs) and HB vaccine core antigen (anti-HBc) were measured on...
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Sociedade Brasileira de Medicina Tropical (SBMT)
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Online Access: | https://doi.org/10.1590/S0037-86822012000200024 https://doaj.org/article/4066263c18de455a94edd6c32d71cdde |
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ftdoajarticles:oai:doaj.org/article:4066263c18de455a94edd6c32d71cdde 2023-05-15T15:02:32+02:00 Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study Glauco Danielle Fagundes Fábio de Oliveira Tabalipa Jane da Silva 2012-04-01T00:00:00Z https://doi.org/10.1590/S0037-86822012000200024 https://doaj.org/article/4066263c18de455a94edd6c32d71cdde EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000200024&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000200024 https://doaj.org/article/4066263c18de455a94edd6c32d71cdde Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 2, Pp 260-262 (2012) Vírus da hepatite B Vacinação Anti-HBS Anti-HBc HBsAg Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles https://doi.org/10.1590/S0037-86822012000200024 2022-12-31T02:35:52Z INTRODUCTION: It is known that the hepatitis B (HB) vaccine is effective, but it is alarming that sudden drops of antibody levels may coincide with the onset of adolescence. METHODS: Antibody levels against HB vaccine surface antigen (anti-HBs) and HB vaccine core antigen (anti-HBc) were measured on the blood samples of children with a mean age of 11.4 years. RESULTS: About 54.8% had protective levels of anti-HBs. Of those who were anti-HBc-positive (4.4%), an average of 218.4 anti-HBs mIU/mL was found. CONCLUSIONS: Immunological protection was found in the majority of children. However, more studies are needed to elucidate the heritability of nonresponders and establish strategies against such events. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 45 2 260 262 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Vírus da hepatite B Vacinação Anti-HBS Anti-HBc HBsAg Arctic medicine. Tropical medicine RC955-962 |
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Vírus da hepatite B Vacinação Anti-HBS Anti-HBc HBsAg Arctic medicine. Tropical medicine RC955-962 Glauco Danielle Fagundes Fábio de Oliveira Tabalipa Jane da Silva Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study |
topic_facet |
Vírus da hepatite B Vacinação Anti-HBS Anti-HBc HBsAg Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: It is known that the hepatitis B (HB) vaccine is effective, but it is alarming that sudden drops of antibody levels may coincide with the onset of adolescence. METHODS: Antibody levels against HB vaccine surface antigen (anti-HBs) and HB vaccine core antigen (anti-HBc) were measured on the blood samples of children with a mean age of 11.4 years. RESULTS: About 54.8% had protective levels of anti-HBs. Of those who were anti-HBc-positive (4.4%), an average of 218.4 anti-HBs mIU/mL was found. CONCLUSIONS: Immunological protection was found in the majority of children. However, more studies are needed to elucidate the heritability of nonresponders and establish strategies against such events. |
format |
Article in Journal/Newspaper |
author |
Glauco Danielle Fagundes Fábio de Oliveira Tabalipa Jane da Silva |
author_facet |
Glauco Danielle Fagundes Fábio de Oliveira Tabalipa Jane da Silva |
author_sort |
Glauco Danielle Fagundes |
title |
Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study |
title_short |
Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study |
title_full |
Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study |
title_fullStr |
Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study |
title_full_unstemmed |
Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study |
title_sort |
antibody levels in children after 10 years of vaccination against hepatitis b: a brazilian community-based study |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2012 |
url |
https://doi.org/10.1590/S0037-86822012000200024 https://doaj.org/article/4066263c18de455a94edd6c32d71cdde |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 2, Pp 260-262 (2012) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000200024&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000200024 https://doaj.org/article/4066263c18de455a94edd6c32d71cdde |
op_doi |
https://doi.org/10.1590/S0037-86822012000200024 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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45 |
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2 |
container_start_page |
260 |
op_container_end_page |
262 |
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