Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines?
Abstract Background To optimize the fluid status of adult patients with severe malaria, World Health Organization (WHO) guidelines recommend the insertion of a central venous catheter (CVC) and a target central venous pressure (CVP) of 0-5 cmH 2 O. However there are few data from clinical trials to...
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ftdoajarticles:oai:doaj.org/article:3f60c971379f4b7ba0ff0d4317524173 2023-05-15T15:10:36+02:00 Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? Hanson Josh Lam Sophia WK Mohanty Sanjib Alam Shamshul Hasan Md Mahtab Lee Sue J Schultz Marcus J Charunwatthana Prakaykaew Cohen Sophie Kabir Ashraf Mishra Saroj Day Nicholas PJ White Nicholas J Dondorp Arjen M 2011-11-01T00:00:00Z https://doi.org/10.1186/1475-2875-10-342 https://doaj.org/article/3f60c971379f4b7ba0ff0d4317524173 EN eng BMC http://www.malariajournal.com/content/10/1/342 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-342 1475-2875 https://doaj.org/article/3f60c971379f4b7ba0ff0d4317524173 Malaria Journal, Vol 10, Iss 1, p 342 (2011) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2011 ftdoajarticles https://doi.org/10.1186/1475-2875-10-342 2022-12-31T06:55:40Z Abstract Background To optimize the fluid status of adult patients with severe malaria, World Health Organization (WHO) guidelines recommend the insertion of a central venous catheter (CVC) and a target central venous pressure (CVP) of 0-5 cmH 2 O. However there are few data from clinical trials to support this recommendation. Methods Twenty-eight adult Indian and Bangladeshi patients admitted to the intensive care unit with severe falciparum malaria were enrolled in the study. All patients had a CVC inserted and had regular CVP measurements recorded. The CVP measurements were compared with markers of disease severity, clinical endpoints and volumetric measures derived from transpulmonary thermodilution. Results There was no correlation between the admission CVP and patient outcome (p = 0.67) or disease severity (p = 0.33). There was no correlation between the baseline CVP and the concomitant extravascular lung water (p = 0.62), global end diastolic volume (p = 0.88) or cardiac index (p = 0.44). There was no correlation between the baseline CVP and the likelihood of a patient being fluid responsive (p = 0.37). On the occasions when the CVP was in the WHO target range patients were usually hypovolaemic and often had pulmonary oedema by volumetric measures. Seven of 28 patients suffered a complication of the CVC insertion, although none were fatal. Conclusion The WHO recommendation for the routine insertion of a CVC, and the maintenance of a CVP of 0-5 cmH 2 O in adults with severe malaria, should be reconsidered. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Indian Malaria Journal 10 1 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Hanson Josh Lam Sophia WK Mohanty Sanjib Alam Shamshul Hasan Md Mahtab Lee Sue J Schultz Marcus J Charunwatthana Prakaykaew Cohen Sophie Kabir Ashraf Mishra Saroj Day Nicholas PJ White Nicholas J Dondorp Arjen M Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background To optimize the fluid status of adult patients with severe malaria, World Health Organization (WHO) guidelines recommend the insertion of a central venous catheter (CVC) and a target central venous pressure (CVP) of 0-5 cmH 2 O. However there are few data from clinical trials to support this recommendation. Methods Twenty-eight adult Indian and Bangladeshi patients admitted to the intensive care unit with severe falciparum malaria were enrolled in the study. All patients had a CVC inserted and had regular CVP measurements recorded. The CVP measurements were compared with markers of disease severity, clinical endpoints and volumetric measures derived from transpulmonary thermodilution. Results There was no correlation between the admission CVP and patient outcome (p = 0.67) or disease severity (p = 0.33). There was no correlation between the baseline CVP and the concomitant extravascular lung water (p = 0.62), global end diastolic volume (p = 0.88) or cardiac index (p = 0.44). There was no correlation between the baseline CVP and the likelihood of a patient being fluid responsive (p = 0.37). On the occasions when the CVP was in the WHO target range patients were usually hypovolaemic and often had pulmonary oedema by volumetric measures. Seven of 28 patients suffered a complication of the CVC insertion, although none were fatal. Conclusion The WHO recommendation for the routine insertion of a CVC, and the maintenance of a CVP of 0-5 cmH 2 O in adults with severe malaria, should be reconsidered. |
format |
Article in Journal/Newspaper |
author |
Hanson Josh Lam Sophia WK Mohanty Sanjib Alam Shamshul Hasan Md Mahtab Lee Sue J Schultz Marcus J Charunwatthana Prakaykaew Cohen Sophie Kabir Ashraf Mishra Saroj Day Nicholas PJ White Nicholas J Dondorp Arjen M |
author_facet |
Hanson Josh Lam Sophia WK Mohanty Sanjib Alam Shamshul Hasan Md Mahtab Lee Sue J Schultz Marcus J Charunwatthana Prakaykaew Cohen Sophie Kabir Ashraf Mishra Saroj Day Nicholas PJ White Nicholas J Dondorp Arjen M |
author_sort |
Hanson Josh |
title |
Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? |
title_short |
Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? |
title_full |
Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? |
title_fullStr |
Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? |
title_full_unstemmed |
Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? |
title_sort |
central venous catheter use in severe malaria: time to reconsider the world health organization guidelines? |
publisher |
BMC |
publishDate |
2011 |
url |
https://doi.org/10.1186/1475-2875-10-342 https://doaj.org/article/3f60c971379f4b7ba0ff0d4317524173 |
geographic |
Arctic Indian |
geographic_facet |
Arctic Indian |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 10, Iss 1, p 342 (2011) |
op_relation |
http://www.malariajournal.com/content/10/1/342 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-342 1475-2875 https://doaj.org/article/3f60c971379f4b7ba0ff0d4317524173 |
op_doi |
https://doi.org/10.1186/1475-2875-10-342 |
container_title |
Malaria Journal |
container_volume |
10 |
container_issue |
1 |
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1766341591568482304 |