A Retrospective Study on Genetic Heterogeneity within Treponema Strains: Subpopulations Are Genetically Distinct in a Limited Number of Positions.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Darina Čejková, Michal Strouhal, Steven J Norris, George M Weinstock, David Šmajs
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2015
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Gauthier
• Online Access: https://doi.org/10.1371/journal.pntd.0004110; https://doaj.org/article/3ddd1ef3aacb46c596f3f8723b5a9c2f

Pathogenic uncultivable treponemes comprise human and animal pathogens including agents of syphilis, yaws, bejel, pinta, and venereal spirochetosis in rabbits and hares. A set of 10 treponemal genome sequences including those of 4 Treponema pallidum ssp. pallidum (TPA) strains (Nichols, DAL-1, Mexic...