Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis
Aim. To study the spectrum of serum fatty acids (SSFA) and the composition of blood lipids in cholelithiasis (CL) in various ethnic groups of East Siberia. Subjects and methods. A clinical and epidemiological study was conducted, during which ultrasonography and oral cholecystography were used to ex...
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"Consilium Medicum" Publishing house
2017
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Online Access: | https://doi.org/10.17116/terarkh201789266-69 https://doaj.org/article/3cdbb61d3c094fc0bd31984629ee77a7 |
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ftdoajarticles:oai:doaj.org/article:3cdbb61d3c094fc0bd31984629ee77a7 2023-05-15T16:09:13+02:00 Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis Yu L Tonkikh V V Tsukanov E V Kasparov E P Bronnikova A V Vasyutin 2017-02-01T00:00:00Z https://doi.org/10.17116/terarkh201789266-69 https://doaj.org/article/3cdbb61d3c094fc0bd31984629ee77a7 RU rus "Consilium Medicum" Publishing house https://ter-arkhiv.ru/0040-3660/article/viewFile/32205/pdf https://doaj.org/toc/0040-3660 https://doaj.org/toc/2309-5342 0040-3660 2309-5342 doi:10.17116/terarkh201789266-69 https://doaj.org/article/3cdbb61d3c094fc0bd31984629ee77a7 Терапевтический архив, Vol 89, Iss 2, Pp 66-69 (2017) cholelithiasis fatty acids blood lipids Medicine R article 2017 ftdoajarticles https://doi.org/10.17116/terarkh201789266-69 2022-12-31T12:12:51Z Aim. To study the spectrum of serum fatty acids (SSFA) and the composition of blood lipids in cholelithiasis (CL) in various ethnic groups of East Siberia. Subjects and methods. A clinical and epidemiological study was conducted, during which ultrasonography and oral cholecystography were used to examine 991 Khakases and 934 Europoids in Khakassia and 652 Evenks and 996 Europoids in Evenkia. Biochemical tests were performed to determine serum lipids in 20% of the random sample. Gas liquid chromatography was applied to investigate ASSFA in 220 patients in Khakassia and 157 people in Evenkia. Results. The manifestations of hyperlipidemia were detected in the Europoids with CL in Evenkia and Khakassia. These changes were less pronounced in the Evenks with CL and absent in the Khakases with CL. In all populations, the blood levels of saturated FAs and ratios of saturated to unsaturated FAs were considerably higher in the patients with CL than in the healthy individuals. Conclusion. The higher levels of saturated FAs and the lower proportion of serum unsaturated FAs are a universal marker of lipid metabolic disturbances in patients with CL in genetically different populations. Article in Journal/Newspaper Evenks Siberia Directory of Open Access Journals: DOAJ Articles Terapevticheskii arkhiv 89 2 66 69 |
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Directory of Open Access Journals: DOAJ Articles |
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Russian |
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cholelithiasis fatty acids blood lipids Medicine R |
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cholelithiasis fatty acids blood lipids Medicine R Yu L Tonkikh V V Tsukanov E V Kasparov E P Bronnikova A V Vasyutin Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis |
topic_facet |
cholelithiasis fatty acids blood lipids Medicine R |
description |
Aim. To study the spectrum of serum fatty acids (SSFA) and the composition of blood lipids in cholelithiasis (CL) in various ethnic groups of East Siberia. Subjects and methods. A clinical and epidemiological study was conducted, during which ultrasonography and oral cholecystography were used to examine 991 Khakases and 934 Europoids in Khakassia and 652 Evenks and 996 Europoids in Evenkia. Biochemical tests were performed to determine serum lipids in 20% of the random sample. Gas liquid chromatography was applied to investigate ASSFA in 220 patients in Khakassia and 157 people in Evenkia. Results. The manifestations of hyperlipidemia were detected in the Europoids with CL in Evenkia and Khakassia. These changes were less pronounced in the Evenks with CL and absent in the Khakases with CL. In all populations, the blood levels of saturated FAs and ratios of saturated to unsaturated FAs were considerably higher in the patients with CL than in the healthy individuals. Conclusion. The higher levels of saturated FAs and the lower proportion of serum unsaturated FAs are a universal marker of lipid metabolic disturbances in patients with CL in genetically different populations. |
format |
Article in Journal/Newspaper |
author |
Yu L Tonkikh V V Tsukanov E V Kasparov E P Bronnikova A V Vasyutin |
author_facet |
Yu L Tonkikh V V Tsukanov E V Kasparov E P Bronnikova A V Vasyutin |
author_sort |
Yu L Tonkikh |
title |
Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis |
title_short |
Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis |
title_full |
Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis |
title_fullStr |
Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis |
title_full_unstemmed |
Change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis |
title_sort |
change in the ratio of blood saturated to unsaturated fatty acids is a universal marker of lipid metabolic disorder in patients with cholelithiasis |
publisher |
"Consilium Medicum" Publishing house |
publishDate |
2017 |
url |
https://doi.org/10.17116/terarkh201789266-69 https://doaj.org/article/3cdbb61d3c094fc0bd31984629ee77a7 |
genre |
Evenks Siberia |
genre_facet |
Evenks Siberia |
op_source |
Терапевтический архив, Vol 89, Iss 2, Pp 66-69 (2017) |
op_relation |
https://ter-arkhiv.ru/0040-3660/article/viewFile/32205/pdf https://doaj.org/toc/0040-3660 https://doaj.org/toc/2309-5342 0040-3660 2309-5342 doi:10.17116/terarkh201789266-69 https://doaj.org/article/3cdbb61d3c094fc0bd31984629ee77a7 |
op_doi |
https://doi.org/10.17116/terarkh201789266-69 |
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Terapevticheskii arkhiv |
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89 |
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2 |
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66 |
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69 |
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