Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study
Abstract Background Herpes simplex virus type 2 (HSV-2) infection is the most common cause of genital ulcer disease (GUD) worldwide. Mother to child transmission causes high morbidity and mortality among infants. Russia is on the brink of a generalized HIV-epidemic, but Arkhangelsk is still a low-pr...
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ftdoajarticles:oai:doaj.org/article:3c86abeecf61452aaf4ba9de1c33a3ad 2023-05-15T15:23:37+02:00 Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study Tatiana Balaeva Andrej M. Grjibovski Oleg Sidorenkov Olga Samodova Natalia Firsova Anatoly Sannikov Elise Klouman 2016-10-01T00:00:00Z https://doi.org/10.1186/s12879-016-1954-8 https://doaj.org/article/3c86abeecf61452aaf4ba9de1c33a3ad EN eng BMC http://link.springer.com/article/10.1186/s12879-016-1954-8 https://doaj.org/toc/1471-2334 doi:10.1186/s12879-016-1954-8 1471-2334 https://doaj.org/article/3c86abeecf61452aaf4ba9de1c33a3ad BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-12 (2016) Herpes simplex virus type 2 HSV-2 Correlates of HSV-2 Self-reported STIs Seroprevalence Population-based Infectious and parasitic diseases RC109-216 article 2016 ftdoajarticles https://doi.org/10.1186/s12879-016-1954-8 2022-12-31T16:04:46Z Abstract Background Herpes simplex virus type 2 (HSV-2) infection is the most common cause of genital ulcer disease (GUD) worldwide. Mother to child transmission causes high morbidity and mortality among infants. Russia is on the brink of a generalized HIV-epidemic, but Arkhangelsk is still a low-prevalence area. HSV-2 infection is associated with a three-fold increased risk of HIV-infection. The evidence on the seroprevalence of HSV-2 in Russia is limited. The aim of this study was to assess HSV-2 seroprevalence and correlates among young adults in the city of Arkhangelsk. Methods 1243 adults aged 18-39 years participated in a cross-sectional population-based study, recruited by a public opinion agency applying a quota sampling method to achieve a data set with similar age- and sex-distribution as the population in Arkhangelsk. All participants completed a standardized, self-administrated questionnaire and were tested for HSV-2. Associations between HSV-2 seropositivity and selected sociodemographic and behavioral factors, and self-reported history of sexually transmitted infections (STIs) were studied by multivariable logistic regression. Results HSV-2 seroprevalence was 18.8 %: 12.2 % (95 % confidence interval, CI 9.7-15.2) among men and 24.0 % (95 % CI 20.1-27.3) among women. Among men, HSV-2 positivity was associated with being divorced/widowed (OR = 2.85, 95 % CI 1.06-7.70), cohabitation (OR = 2.45, 95 % CI 1.07-5.62), and a history of STIs (OR = 2.11, 95 % CI 1.14-3.91). In women, HSV-2 positivity was associated with high income (OR = 3.11, 95 % CI 1.45-6.71) and having a lifetime number of sexual partners between 2 and 5 (OR = 2.72, 95 % CI 1.14-6.51), whereas sexual debut at age 18 years or older was inversely associated with the outcome (OR = 0.47, 95 % CI 0.31-0.72). In both sexes, increasing age was the strongest correlate of HSV-2 seropositivity in multivariable analyses. Conclusion The HSV-2 seroprevalence was twice as high in women than in men and increased with age in both sexes, and similar to ... Article in Journal/Newspaper Arkhangelsk Northwest Russia Directory of Open Access Journals: DOAJ Articles BMC Infectious Diseases 16 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Herpes simplex virus type 2 HSV-2 Correlates of HSV-2 Self-reported STIs Seroprevalence Population-based Infectious and parasitic diseases RC109-216 |
spellingShingle |
Herpes simplex virus type 2 HSV-2 Correlates of HSV-2 Self-reported STIs Seroprevalence Population-based Infectious and parasitic diseases RC109-216 Tatiana Balaeva Andrej M. Grjibovski Oleg Sidorenkov Olga Samodova Natalia Firsova Anatoly Sannikov Elise Klouman Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study |
topic_facet |
Herpes simplex virus type 2 HSV-2 Correlates of HSV-2 Self-reported STIs Seroprevalence Population-based Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Herpes simplex virus type 2 (HSV-2) infection is the most common cause of genital ulcer disease (GUD) worldwide. Mother to child transmission causes high morbidity and mortality among infants. Russia is on the brink of a generalized HIV-epidemic, but Arkhangelsk is still a low-prevalence area. HSV-2 infection is associated with a three-fold increased risk of HIV-infection. The evidence on the seroprevalence of HSV-2 in Russia is limited. The aim of this study was to assess HSV-2 seroprevalence and correlates among young adults in the city of Arkhangelsk. Methods 1243 adults aged 18-39 years participated in a cross-sectional population-based study, recruited by a public opinion agency applying a quota sampling method to achieve a data set with similar age- and sex-distribution as the population in Arkhangelsk. All participants completed a standardized, self-administrated questionnaire and were tested for HSV-2. Associations between HSV-2 seropositivity and selected sociodemographic and behavioral factors, and self-reported history of sexually transmitted infections (STIs) were studied by multivariable logistic regression. Results HSV-2 seroprevalence was 18.8 %: 12.2 % (95 % confidence interval, CI 9.7-15.2) among men and 24.0 % (95 % CI 20.1-27.3) among women. Among men, HSV-2 positivity was associated with being divorced/widowed (OR = 2.85, 95 % CI 1.06-7.70), cohabitation (OR = 2.45, 95 % CI 1.07-5.62), and a history of STIs (OR = 2.11, 95 % CI 1.14-3.91). In women, HSV-2 positivity was associated with high income (OR = 3.11, 95 % CI 1.45-6.71) and having a lifetime number of sexual partners between 2 and 5 (OR = 2.72, 95 % CI 1.14-6.51), whereas sexual debut at age 18 years or older was inversely associated with the outcome (OR = 0.47, 95 % CI 0.31-0.72). In both sexes, increasing age was the strongest correlate of HSV-2 seropositivity in multivariable analyses. Conclusion The HSV-2 seroprevalence was twice as high in women than in men and increased with age in both sexes, and similar to ... |
format |
Article in Journal/Newspaper |
author |
Tatiana Balaeva Andrej M. Grjibovski Oleg Sidorenkov Olga Samodova Natalia Firsova Anatoly Sannikov Elise Klouman |
author_facet |
Tatiana Balaeva Andrej M. Grjibovski Oleg Sidorenkov Olga Samodova Natalia Firsova Anatoly Sannikov Elise Klouman |
author_sort |
Tatiana Balaeva |
title |
Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study |
title_short |
Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study |
title_full |
Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study |
title_fullStr |
Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study |
title_full_unstemmed |
Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study |
title_sort |
seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in arkhangelsk, northwest russia: a population-based cross-sectional study |
publisher |
BMC |
publishDate |
2016 |
url |
https://doi.org/10.1186/s12879-016-1954-8 https://doaj.org/article/3c86abeecf61452aaf4ba9de1c33a3ad |
genre |
Arkhangelsk Northwest Russia |
genre_facet |
Arkhangelsk Northwest Russia |
op_source |
BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-12 (2016) |
op_relation |
http://link.springer.com/article/10.1186/s12879-016-1954-8 https://doaj.org/toc/1471-2334 doi:10.1186/s12879-016-1954-8 1471-2334 https://doaj.org/article/3c86abeecf61452aaf4ba9de1c33a3ad |
op_doi |
https://doi.org/10.1186/s12879-016-1954-8 |
container_title |
BMC Infectious Diseases |
container_volume |
16 |
container_issue |
1 |
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1766354274920431616 |