Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health?
This study focused on Oeosophagostomum sp., and more especially on O. bifurcum, as a parasite that can be lethal to humans and is widespread among humans and monkeys in endemic regions, but has not yet been documented in apes. Its epidemiology and the role played by non-human primates in its transmi...
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ftdoajarticles:oai:doaj.org/article:3c7a5e213ead4f1a8e50b578a218c987 2023-05-15T15:15:27+02:00 Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health? Sabrina Krief Benjamin Vermeulen Sophie Lafosse John M Kasenene Adélaïde Nieguitsila Madeleine Berthelemy Monique L'hostis Odile Bain Jacques Guillot 2010-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0000630 https://doaj.org/article/3c7a5e213ead4f1a8e50b578a218c987 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC2838776?pdf=render https://doaj.org/toc/1935-2735 1935-2735 doi:10.1371/journal.pntd.0000630 https://doaj.org/article/3c7a5e213ead4f1a8e50b578a218c987 PLoS Neglected Tropical Diseases, Vol 4, Iss 3, p e630 (2010) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2010 ftdoajarticles https://doi.org/10.1371/journal.pntd.0000630 2022-12-31T00:05:02Z This study focused on Oeosophagostomum sp., and more especially on O. bifurcum, as a parasite that can be lethal to humans and is widespread among humans and monkeys in endemic regions, but has not yet been documented in apes. Its epidemiology and the role played by non-human primates in its transmission are still poorly understood. O. stephanostomum was the only species diagnosed so far in chimpanzees. Until recently, O. bifurcum was assumed to have a high zoonotic potential, but recent findings tend to demonstrate that O. bifurcum of non-human primates and humans might be genetically distinct. As the closest relative to human beings, and a species living in spatial proximity to humans in the field site studied, Pan troglodytes is thus an interesting host to investigate. Recently, a role for chimpanzees in the emergence of HIV and malaria in humans has been documented. In the framework of our long-term health monitoring of wild chimpanzees from Kibale National Park in Western Uganda, we analysed 311 samples of faeces. Coproscopy revealed that high-ranking males are more infected than other individuals. These chimpanzees are also the more frequent crop-raiders. Results from PCR assays conducted on larvae and dried faeces also revealed that O. stephanostomum as well as O. bifurcum are infecting chimpanzees, both species co-existing in the same individuals. Because contacts between humans and great apes are increasing with ecotourism and forest fragmentation in areas of high population density, this paper emphasizes that the presence of potential zoonotic parasites should be viewed as a major concern for public health. Investigations of the parasite status of people living around the park or working inside as well as sympatric non-human primates should be planned, and further research might reveal this as a promising aspect of efforts to reinforce measures against crop-raiding. Article in Journal/Newspaper Arctic Human health Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 4 3 e630 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Sabrina Krief Benjamin Vermeulen Sophie Lafosse John M Kasenene Adélaïde Nieguitsila Madeleine Berthelemy Monique L'hostis Odile Bain Jacques Guillot Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health? |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
This study focused on Oeosophagostomum sp., and more especially on O. bifurcum, as a parasite that can be lethal to humans and is widespread among humans and monkeys in endemic regions, but has not yet been documented in apes. Its epidemiology and the role played by non-human primates in its transmission are still poorly understood. O. stephanostomum was the only species diagnosed so far in chimpanzees. Until recently, O. bifurcum was assumed to have a high zoonotic potential, but recent findings tend to demonstrate that O. bifurcum of non-human primates and humans might be genetically distinct. As the closest relative to human beings, and a species living in spatial proximity to humans in the field site studied, Pan troglodytes is thus an interesting host to investigate. Recently, a role for chimpanzees in the emergence of HIV and malaria in humans has been documented. In the framework of our long-term health monitoring of wild chimpanzees from Kibale National Park in Western Uganda, we analysed 311 samples of faeces. Coproscopy revealed that high-ranking males are more infected than other individuals. These chimpanzees are also the more frequent crop-raiders. Results from PCR assays conducted on larvae and dried faeces also revealed that O. stephanostomum as well as O. bifurcum are infecting chimpanzees, both species co-existing in the same individuals. Because contacts between humans and great apes are increasing with ecotourism and forest fragmentation in areas of high population density, this paper emphasizes that the presence of potential zoonotic parasites should be viewed as a major concern for public health. Investigations of the parasite status of people living around the park or working inside as well as sympatric non-human primates should be planned, and further research might reveal this as a promising aspect of efforts to reinforce measures against crop-raiding. |
format |
Article in Journal/Newspaper |
author |
Sabrina Krief Benjamin Vermeulen Sophie Lafosse John M Kasenene Adélaïde Nieguitsila Madeleine Berthelemy Monique L'hostis Odile Bain Jacques Guillot |
author_facet |
Sabrina Krief Benjamin Vermeulen Sophie Lafosse John M Kasenene Adélaïde Nieguitsila Madeleine Berthelemy Monique L'hostis Odile Bain Jacques Guillot |
author_sort |
Sabrina Krief |
title |
Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health? |
title_short |
Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health? |
title_full |
Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health? |
title_fullStr |
Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health? |
title_full_unstemmed |
Nodular worm infection in wild chimpanzees in Western Uganda: a risk for human health? |
title_sort |
nodular worm infection in wild chimpanzees in western uganda: a risk for human health? |
publisher |
Public Library of Science (PLoS) |
publishDate |
2010 |
url |
https://doi.org/10.1371/journal.pntd.0000630 https://doaj.org/article/3c7a5e213ead4f1a8e50b578a218c987 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Human health |
genre_facet |
Arctic Human health |
op_source |
PLoS Neglected Tropical Diseases, Vol 4, Iss 3, p e630 (2010) |
op_relation |
http://europepmc.org/articles/PMC2838776?pdf=render https://doaj.org/toc/1935-2735 1935-2735 doi:10.1371/journal.pntd.0000630 https://doaj.org/article/3c7a5e213ead4f1a8e50b578a218c987 |
op_doi |
https://doi.org/10.1371/journal.pntd.0000630 |
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PLoS Neglected Tropical Diseases |
container_volume |
4 |
container_issue |
3 |
container_start_page |
e630 |
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1766345812416135168 |