Treatment of severe chromoblastomycosis with itraconazole and 5-flucytosine association

Chromoblastomycosis is a chronic human melanized fungi infection of the subcutaneous tissue caused by traumatic inoculation of a specific group of dematiaceous fungi through the skin, often found in barefooted agricultural workers, in tropical and subtropical climate countries. We report the case of...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Vicente Sperb Antonello, Marcelo Campos Appel da Silva, Eduardo Cambruzzi, Dimas Alexandre Kliemann, Breno Riegel Santos, Flávio Queiroz-Telles
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2010
Subjects:
Chromoblastomycosis
Itraconazole
5-Flucytosine
Subcutaneous mycoses
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/S0036-46652010000600008
https://doaj.org/article/3c4fd4d96b24443ebe574dff876cbded
Description
Summary:Chromoblastomycosis is a chronic human melanized fungi infection of the subcutaneous tissue caused by traumatic inoculation of a specific group of dematiaceous fungi through the skin, often found in barefooted agricultural workers, in tropical and subtropical climate countries. We report the case of a male patient presenting a slow-growing pruriginous lesion on the limbs for 20 years, mistreated over that time, which was diagnosed and successfully treated as chromoblastomycosis. Besides the prevalence of this disease, treatment is still a clinical challenge.

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