Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria
The anticoagulant rodenticides are the most commonly used toxicants to control rodents nowadays. Therefore, developing resistance to them is an issue of great importance for pest control. The aim of this study was to investigate the sensitivity of synanthropic rodents in the Stara Zagora region, Bul...
Published in: | Macedonian Veterinary Review |
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Ss.Cyril and Methodius University, Skopje
2019
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ftdoajarticles:oai:doaj.org/article:3b4ab06814994e8880211d88d825749c 2023-05-15T18:05:31+02:00 Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria Georgi G. Zhelev Kojcho P. Koev Vladimir D. Dimitrov Vladimir S. Petrov 2019-10-01T00:00:00Z https://doi.org/10.2478/macvetrev-2019-0010 https://doaj.org/article/3b4ab06814994e8880211d88d825749c EN eng Ss.Cyril and Methodius University, Skopje https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2019_0010 https://doaj.org/toc/1409-7621 https://doaj.org/toc/1857-7415 doi:10.2478/macvetrev-2019-0010 1409-7621 1857-7415 https://doaj.org/article/3b4ab06814994e8880211d88d825749c Macedonian Veterinary Review, Vol 42, Iss 1, Pp 61-70 (2019) resistance anticoagulant rodenticides synantropic rodents Veterinary medicine SF600-1100 article 2019 ftdoajarticles https://doi.org/10.2478/macvetrev-2019-0010 2022-12-31T08:35:14Z The anticoagulant rodenticides are the most commonly used toxicants to control rodents nowadays. Therefore, developing resistance to them is an issue of great importance for pest control. The aim of this study was to investigate the sensitivity of synanthropic rodents in the Stara Zagora region, Bulgaria to some of the most significant first (warfarin and coumatetralyl) and second (bromadiolone and brodifacoum) generation anticoagulants. Resistance tests were carried out by a standard protocol using lethal feeding period tests and blood clotting response tests according to the European and Mediterranean Plant Protection Organization (Paris, France) standard. Studies were performed on 278 wild synanthropic rodents – 67 house mice (Mus musculus), 153 roof rats (Rattus rattus) and 58 brown rats (Rattus norvegicus). The rodents belonged to 11 populations inhabiting 9 animal farms in the region of Stara Zagora, Southern Bulgaria. High-level resistance to warfarinwas established in 100% of surveyed house mice and 92.1% of roof rats. Resistance to coumatetralyl was registered in 62.5% of the tested roof rats. Low-level resistance to bromadiolone was found in 38.5% of the surveyed roof rats and 23.1% of house mice. There was no resistance registered in brown rats. The sensitivity of all three rodent species to the strategic anticoagulant brodifacoum was high, and there were no signs of resistance. The results proved the resistance among synanthropic rodents and led to the conclusion that the resistance in house mice and roof rats to warfarin and coumatetralyl tends to be the main issue in pest control. Article in Journal/Newspaper Rattus rattus Directory of Open Access Journals: DOAJ Articles Macedonian Veterinary Review 42 1 61 70 |
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topic |
resistance anticoagulant rodenticides synantropic rodents Veterinary medicine SF600-1100 |
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resistance anticoagulant rodenticides synantropic rodents Veterinary medicine SF600-1100 Georgi G. Zhelev Kojcho P. Koev Vladimir D. Dimitrov Vladimir S. Petrov Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria |
topic_facet |
resistance anticoagulant rodenticides synantropic rodents Veterinary medicine SF600-1100 |
description |
The anticoagulant rodenticides are the most commonly used toxicants to control rodents nowadays. Therefore, developing resistance to them is an issue of great importance for pest control. The aim of this study was to investigate the sensitivity of synanthropic rodents in the Stara Zagora region, Bulgaria to some of the most significant first (warfarin and coumatetralyl) and second (bromadiolone and brodifacoum) generation anticoagulants. Resistance tests were carried out by a standard protocol using lethal feeding period tests and blood clotting response tests according to the European and Mediterranean Plant Protection Organization (Paris, France) standard. Studies were performed on 278 wild synanthropic rodents – 67 house mice (Mus musculus), 153 roof rats (Rattus rattus) and 58 brown rats (Rattus norvegicus). The rodents belonged to 11 populations inhabiting 9 animal farms in the region of Stara Zagora, Southern Bulgaria. High-level resistance to warfarinwas established in 100% of surveyed house mice and 92.1% of roof rats. Resistance to coumatetralyl was registered in 62.5% of the tested roof rats. Low-level resistance to bromadiolone was found in 38.5% of the surveyed roof rats and 23.1% of house mice. There was no resistance registered in brown rats. The sensitivity of all three rodent species to the strategic anticoagulant brodifacoum was high, and there were no signs of resistance. The results proved the resistance among synanthropic rodents and led to the conclusion that the resistance in house mice and roof rats to warfarin and coumatetralyl tends to be the main issue in pest control. |
format |
Article in Journal/Newspaper |
author |
Georgi G. Zhelev Kojcho P. Koev Vladimir D. Dimitrov Vladimir S. Petrov |
author_facet |
Georgi G. Zhelev Kojcho P. Koev Vladimir D. Dimitrov Vladimir S. Petrov |
author_sort |
Georgi G. Zhelev |
title |
Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria |
title_short |
Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria |
title_full |
Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria |
title_fullStr |
Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria |
title_full_unstemmed |
Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria |
title_sort |
anticoagulant resistance in synanthropic rodents in the stara zagora region, bulgaria |
publisher |
Ss.Cyril and Methodius University, Skopje |
publishDate |
2019 |
url |
https://doi.org/10.2478/macvetrev-2019-0010 https://doaj.org/article/3b4ab06814994e8880211d88d825749c |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Macedonian Veterinary Review, Vol 42, Iss 1, Pp 61-70 (2019) |
op_relation |
https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2019_0010 https://doaj.org/toc/1409-7621 https://doaj.org/toc/1857-7415 doi:10.2478/macvetrev-2019-0010 1409-7621 1857-7415 https://doaj.org/article/3b4ab06814994e8880211d88d825749c |
op_doi |
https://doi.org/10.2478/macvetrev-2019-0010 |
container_title |
Macedonian Veterinary Review |
container_volume |
42 |
container_issue |
1 |
container_start_page |
61 |
op_container_end_page |
70 |
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1766176991552208896 |