Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases
Abstract INTRODUCTION: Helicobacter pylori, a water contaminant, is the primary pathogenic agent associated with gastric diseases in humans. Exposure to H. pylori is more likely higher in developing countries. This study aimed to evaluate the risk factors associated with H. pylori infection in patie...
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ftdoajarticles:oai:doaj.org/article:3ae1d47399374e7e9fe16ba6bfae4fed 2023-05-15T15:12:28+02:00 Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases Irigrácin Lima Diniz Basílio Maria de Fátima Celino Catão Janilson Dantas de Sousa Carvalho Francisco Paulo Freire-Neto Leonardo Capristano Ferreira Selma Maria Bezerra Jerônimo https://doi.org/10.1590/0037-8682-0412-2016 https://doaj.org/article/3ae1d47399374e7e9fe16ba6bfae4fed EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200183&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0412-2016 https://doaj.org/article/3ae1d47399374e7e9fe16ba6bfae4fed Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 2, Pp 183-189 Epidemiology Helicobacter pylori Risk factors Brazil Arctic medicine. Tropical medicine RC955-962 article ftdoajarticles https://doi.org/10.1590/0037-8682-0412-2016 2022-12-31T02:42:31Z Abstract INTRODUCTION: Helicobacter pylori, a water contaminant, is the primary pathogenic agent associated with gastric diseases in humans. Exposure to H. pylori is more likely higher in developing countries. This study aimed to evaluate the risk factors associated with H. pylori infection in patients undergoing endoscopy to validate the cause of dyspeptic symptoms in an urban population in northeast Brazil and to compare the urease test and polymerase chain reaction assay results with the histopathological findings. METHODS: We evaluated 200 of 759 individuals with dyspeptic complaints from Campina Grande, State of Paraiba, northeast Brazil. Patients underwent endoscopy, followed by gastric biopsies. Logistic regression analysis was performed to adjust for confounders and to determine significant risk factors of dyspeptic disorders. RESULTS: Women accounted for 72.5% (145/200) of the participants. Approximately 59.8% (120/200) of the samples tested positive for H. pylori based on histological examinations. The specificity of polymerase chain reaction assay was higher than that of the urease test (77% vs. 64%, p=0.034). City drinking water [odds ratio (OR): 2.6; 95% confidence interval (CI): 1.3-5.21; p=0.004] and smoking (OR: 4.0; 95% CI: 1.13-14.5; p=0.031) were the risk factors of H. pylori infection. Belching was the most common symptom associated with H. pylori infection (p=0.05). CONCLUSIONS: The increased risk of H. pylori infection associated with non-treated water consumption indicates the need for improvements in public water treatment and better sanitary conditions because these can be a source of not only H. pylori infections but also other water-borne pathogen infections. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 51 2 183 189 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Epidemiology Helicobacter pylori Risk factors Brazil Arctic medicine. Tropical medicine RC955-962 |
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Epidemiology Helicobacter pylori Risk factors Brazil Arctic medicine. Tropical medicine RC955-962 Irigrácin Lima Diniz Basílio Maria de Fátima Celino Catão Janilson Dantas de Sousa Carvalho Francisco Paulo Freire-Neto Leonardo Capristano Ferreira Selma Maria Bezerra Jerônimo Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases |
topic_facet |
Epidemiology Helicobacter pylori Risk factors Brazil Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: Helicobacter pylori, a water contaminant, is the primary pathogenic agent associated with gastric diseases in humans. Exposure to H. pylori is more likely higher in developing countries. This study aimed to evaluate the risk factors associated with H. pylori infection in patients undergoing endoscopy to validate the cause of dyspeptic symptoms in an urban population in northeast Brazil and to compare the urease test and polymerase chain reaction assay results with the histopathological findings. METHODS: We evaluated 200 of 759 individuals with dyspeptic complaints from Campina Grande, State of Paraiba, northeast Brazil. Patients underwent endoscopy, followed by gastric biopsies. Logistic regression analysis was performed to adjust for confounders and to determine significant risk factors of dyspeptic disorders. RESULTS: Women accounted for 72.5% (145/200) of the participants. Approximately 59.8% (120/200) of the samples tested positive for H. pylori based on histological examinations. The specificity of polymerase chain reaction assay was higher than that of the urease test (77% vs. 64%, p=0.034). City drinking water [odds ratio (OR): 2.6; 95% confidence interval (CI): 1.3-5.21; p=0.004] and smoking (OR: 4.0; 95% CI: 1.13-14.5; p=0.031) were the risk factors of H. pylori infection. Belching was the most common symptom associated with H. pylori infection (p=0.05). CONCLUSIONS: The increased risk of H. pylori infection associated with non-treated water consumption indicates the need for improvements in public water treatment and better sanitary conditions because these can be a source of not only H. pylori infections but also other water-borne pathogen infections. |
format |
Article in Journal/Newspaper |
author |
Irigrácin Lima Diniz Basílio Maria de Fátima Celino Catão Janilson Dantas de Sousa Carvalho Francisco Paulo Freire-Neto Leonardo Capristano Ferreira Selma Maria Bezerra Jerônimo |
author_facet |
Irigrácin Lima Diniz Basílio Maria de Fátima Celino Catão Janilson Dantas de Sousa Carvalho Francisco Paulo Freire-Neto Leonardo Capristano Ferreira Selma Maria Bezerra Jerônimo |
author_sort |
Irigrácin Lima Diniz Basílio |
title |
Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases |
title_short |
Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases |
title_full |
Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases |
title_fullStr |
Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases |
title_full_unstemmed |
Risk factors of Helicobacter pylori infection in an urban community in Northeast Brazil and the relationship between the infection and gastric diseases |
title_sort |
risk factors of helicobacter pylori infection in an urban community in northeast brazil and the relationship between the infection and gastric diseases |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
url |
https://doi.org/10.1590/0037-8682-0412-2016 https://doaj.org/article/3ae1d47399374e7e9fe16ba6bfae4fed |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 2, Pp 183-189 |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200183&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0412-2016 https://doaj.org/article/3ae1d47399374e7e9fe16ba6bfae4fed |
op_doi |
https://doi.org/10.1590/0037-8682-0412-2016 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
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51 |
container_issue |
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183 |
op_container_end_page |
189 |
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