Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa
Abstract Background The effectiveness of malaria chemoprophylaxis is limited by the lack of compliance whose determinants are not well known. Methods The compliance with malaria chemoprophylaxis has been estimated and analysed by validated questionnaires administered before and after the short-term...
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ftdoajarticles:oai:doaj.org/article:3a02a7dfe36442e6811d9d2ce747ee86 2023-05-15T15:09:06+02:00 Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa Pradines Bruno Texier Gaetan Orlandi-Pradines Eve Ollivier Lénaick Machault Vanessa Resseguier Noémie Gaudart Jean Buguet Alain Tourette-Turgis Catherine Rogier Christophe 2010-02-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-41 https://doaj.org/article/3a02a7dfe36442e6811d9d2ce747ee86 EN eng BMC http://www.malariajournal.com/content/9/1/41 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-41 1475-2875 https://doaj.org/article/3a02a7dfe36442e6811d9d2ce747ee86 Malaria Journal, Vol 9, Iss 1, p 41 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-41 2022-12-31T00:25:59Z Abstract Background The effectiveness of malaria chemoprophylaxis is limited by the lack of compliance whose determinants are not well known. Methods The compliance with malaria chemoprophylaxis has been estimated and analysed by validated questionnaires administered before and after the short-term missions (about four months) in five tropical African countries of 2,093 French soldiers from 19 military companies involved in a prospective cohort study. "Correct compliance" was defined as "no missed doses" of daily drug intake during the entire mission and was analysed using multiple mixed-effect logistic regression model. Results The averaged prevalence rate of correct compliance was 46.2%, ranging from 9.6%to 76.6% according to the companies. Incorrect compliance was significantly associated with eveningness (p = 0.028), a medical history of clinical malaria (p < 0.001) and a perceived mosquito attractiveness inferior or superior to the others (p < 0.007). Correct compliance was significantly associated with the systematic use of protective measures against mosquito bites (p < 0.001), the type of military operations (combat vs. training activities, p < 0.001) and other individual factors (p < 0.05). Conclusions The identification of circumstances and profiles of persons at higher risk of lack of compliance would pave the way to specifically targeted strategies aimed to improve compliance with malaria chemoprophylaxis and, therefore, its effectiveness. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 9 1 41 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Pradines Bruno Texier Gaetan Orlandi-Pradines Eve Ollivier Lénaick Machault Vanessa Resseguier Noémie Gaudart Jean Buguet Alain Tourette-Turgis Catherine Rogier Christophe Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background The effectiveness of malaria chemoprophylaxis is limited by the lack of compliance whose determinants are not well known. Methods The compliance with malaria chemoprophylaxis has been estimated and analysed by validated questionnaires administered before and after the short-term missions (about four months) in five tropical African countries of 2,093 French soldiers from 19 military companies involved in a prospective cohort study. "Correct compliance" was defined as "no missed doses" of daily drug intake during the entire mission and was analysed using multiple mixed-effect logistic regression model. Results The averaged prevalence rate of correct compliance was 46.2%, ranging from 9.6%to 76.6% according to the companies. Incorrect compliance was significantly associated with eveningness (p = 0.028), a medical history of clinical malaria (p < 0.001) and a perceived mosquito attractiveness inferior or superior to the others (p < 0.007). Correct compliance was significantly associated with the systematic use of protective measures against mosquito bites (p < 0.001), the type of military operations (combat vs. training activities, p < 0.001) and other individual factors (p < 0.05). Conclusions The identification of circumstances and profiles of persons at higher risk of lack of compliance would pave the way to specifically targeted strategies aimed to improve compliance with malaria chemoprophylaxis and, therefore, its effectiveness. |
format |
Article in Journal/Newspaper |
author |
Pradines Bruno Texier Gaetan Orlandi-Pradines Eve Ollivier Lénaick Machault Vanessa Resseguier Noémie Gaudart Jean Buguet Alain Tourette-Turgis Catherine Rogier Christophe |
author_facet |
Pradines Bruno Texier Gaetan Orlandi-Pradines Eve Ollivier Lénaick Machault Vanessa Resseguier Noémie Gaudart Jean Buguet Alain Tourette-Turgis Catherine Rogier Christophe |
author_sort |
Pradines Bruno |
title |
Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa |
title_short |
Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa |
title_full |
Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa |
title_fullStr |
Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa |
title_full_unstemmed |
Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa |
title_sort |
determinants of compliance with malaria chemoprophylaxis among french soldiers during missions in inter-tropical africa |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-41 https://doaj.org/article/3a02a7dfe36442e6811d9d2ce747ee86 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 41 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/41 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-41 1475-2875 https://doaj.org/article/3a02a7dfe36442e6811d9d2ce747ee86 |
op_doi |
https://doi.org/10.1186/1475-2875-9-41 |
container_title |
Malaria Journal |
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9 |
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1 |
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41 |
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1766340328300740608 |