Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)
Abstract Background Fecundity is important for farm blue fox (Vulpes lagopus), who with asthenospermia have be a problem in some of farms in China. A key symptom of asthenospermia is decreased sperm motility. The decreased secreting beta-defensin108 (vBD108) of blue fox is speculated be related to a...
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ftdoajarticles:oai:doaj.org/article:39d4e6000fa54b94bd2285309e8b24cd 2023-05-15T18:42:58+02:00 Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) Ping Wu Tao-lin Liu Ling-ling Li Zhi-ping Liu Li-hong Tian Zhi-jun Hou 2021-01-01T00:00:00Z https://doi.org/10.1186/s12917-020-02697-6 https://doaj.org/article/39d4e6000fa54b94bd2285309e8b24cd EN eng BMC https://doi.org/10.1186/s12917-020-02697-6 https://doaj.org/toc/1746-6148 doi:10.1186/s12917-020-02697-6 1746-6148 https://doaj.org/article/39d4e6000fa54b94bd2285309e8b24cd BMC Veterinary Research, Vol 17, Iss 1, Pp 1-6 (2021) Vulpes lagopus epididymis vBD108 asthenospermia sperm motility Veterinary medicine SF600-1100 article 2021 ftdoajarticles https://doi.org/10.1186/s12917-020-02697-6 2022-12-31T10:59:55Z Abstract Background Fecundity is important for farm blue fox (Vulpes lagopus), who with asthenospermia have be a problem in some of farms in China. A key symptom of asthenospermia is decreased sperm motility. The decreased secreting beta-defensin108 (vBD108) of blue fox is speculated be related to asthenospermia. To clarify this idea, the mRNA expression of vBD108 in testis and epididymis of blue foxes with asthenospermia were detected and compared to the healthy one. The antibody was prepared and analyzed by immunohistochemistry. Results The vBD108 in testis and epididymis was found both in blue fox with asthenospermia and healthy group by the method of immunohistochemistry. The expression of vBD108 mRNA in testes (P < 0.05) and epididymal corpus (P < 0.0001) in asthenospermia group was lower than that in healthy group. Conclusions These results suggested that vBD108 deficiency may related to blue fox asthenospermia. Meanwhile, the study on the blue fox vBD108 provides a hopeful direction to explore the pathogenesis of blue fox asthenospermia in the future. Article in Journal/Newspaper Vulpes lagopus Directory of Open Access Journals: DOAJ Articles BMC Veterinary Research 17 1 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Vulpes lagopus epididymis vBD108 asthenospermia sperm motility Veterinary medicine SF600-1100 |
spellingShingle |
Vulpes lagopus epididymis vBD108 asthenospermia sperm motility Veterinary medicine SF600-1100 Ping Wu Tao-lin Liu Ling-ling Li Zhi-ping Liu Li-hong Tian Zhi-jun Hou Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) |
topic_facet |
Vulpes lagopus epididymis vBD108 asthenospermia sperm motility Veterinary medicine SF600-1100 |
description |
Abstract Background Fecundity is important for farm blue fox (Vulpes lagopus), who with asthenospermia have be a problem in some of farms in China. A key symptom of asthenospermia is decreased sperm motility. The decreased secreting beta-defensin108 (vBD108) of blue fox is speculated be related to asthenospermia. To clarify this idea, the mRNA expression of vBD108 in testis and epididymis of blue foxes with asthenospermia were detected and compared to the healthy one. The antibody was prepared and analyzed by immunohistochemistry. Results The vBD108 in testis and epididymis was found both in blue fox with asthenospermia and healthy group by the method of immunohistochemistry. The expression of vBD108 mRNA in testes (P < 0.05) and epididymal corpus (P < 0.0001) in asthenospermia group was lower than that in healthy group. Conclusions These results suggested that vBD108 deficiency may related to blue fox asthenospermia. Meanwhile, the study on the blue fox vBD108 provides a hopeful direction to explore the pathogenesis of blue fox asthenospermia in the future. |
format |
Article in Journal/Newspaper |
author |
Ping Wu Tao-lin Liu Ling-ling Li Zhi-ping Liu Li-hong Tian Zhi-jun Hou |
author_facet |
Ping Wu Tao-lin Liu Ling-ling Li Zhi-ping Liu Li-hong Tian Zhi-jun Hou |
author_sort |
Ping Wu |
title |
Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) |
title_short |
Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) |
title_full |
Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) |
title_fullStr |
Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) |
title_full_unstemmed |
Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) |
title_sort |
declined expressing mrna of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (vulpes lagopus) |
publisher |
BMC |
publishDate |
2021 |
url |
https://doi.org/10.1186/s12917-020-02697-6 https://doaj.org/article/39d4e6000fa54b94bd2285309e8b24cd |
genre |
Vulpes lagopus |
genre_facet |
Vulpes lagopus |
op_source |
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-6 (2021) |
op_relation |
https://doi.org/10.1186/s12917-020-02697-6 https://doaj.org/toc/1746-6148 doi:10.1186/s12917-020-02697-6 1746-6148 https://doaj.org/article/39d4e6000fa54b94bd2285309e8b24cd |
op_doi |
https://doi.org/10.1186/s12917-020-02697-6 |
container_title |
BMC Veterinary Research |
container_volume |
17 |
container_issue |
1 |
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1766232731113488384 |