Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada.
Echinococcosis is a rare but endemic condition in people in Canada, caused by a zoonotic cestode for which the source of human infection is ingestion of parasite eggs shed by canids. The objectives of this study were to identify risk factors associated with infection and to measure the cost-utility...
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ftdoajarticles:oai:doaj.org/article:39c5b03cd2184d38ac5982ab6bbd3d33 2023-05-15T15:12:51+02:00 Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada. Janna M Schurer Ellen Rafferty Marwa Farag Wu Zeng Emily J Jenkins 2015-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003883 https://doaj.org/article/39c5b03cd2184d38ac5982ab6bbd3d33 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4489623?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003883 https://doaj.org/article/39c5b03cd2184d38ac5982ab6bbd3d33 PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003883 (2015) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2015 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003883 2022-12-31T00:18:51Z Echinococcosis is a rare but endemic condition in people in Canada, caused by a zoonotic cestode for which the source of human infection is ingestion of parasite eggs shed by canids. The objectives of this study were to identify risk factors associated with infection and to measure the cost-utility of introducing an echinococcosis prevention program in a rural area. We analyzed human case reports submitted to the Canadian Institutes for Health Information between 2002 and 2011. Over this 10 year period, there were 48 cases associated with E. granulosus/E. canadensis, 16 with E. multilocularis, and 251 cases of echinococcosis for which species was not identified (total 315 cases). Nationally, annual incidence of echinococcosis was 0.14 cases per 100,000 people, which is likely an underestimate due to under-diagnosis and under-reporting. Risk factors for echinococcosis included female gender, age (>65 years), and residing in one of the northern territories (Nunavut, Yukon, or Northwest Territories). The average cost of treating a case of cystic echinococcosis in Canada was $8,842 CAD. Cost-utility analysis revealed that dosing dogs with praziquantel (a cestocide) at six week intervals to control cystic echinococcosis is not currently cost-effective at a threshold of $20,000-100,000 per Quality Adjusted Life Year (QALY) gained, even in a health region with the highest incidence rate in Canada ($666,978-755,051 per QALY gained). However, threshold analysis demonstrated that the program may become cost-saving at an echinococcosis incidence of 13-85 cases per 100,000 people and therefore, even one additional CE case in a community of 9000 people could result in the monetary benefits of the program outweighing costs. Article in Journal/Newspaper Arctic Northwest Territories Nunavut Yukon Directory of Open Access Journals: DOAJ Articles Arctic Nunavut Yukon Northwest Territories Canada PLOS Neglected Tropical Diseases 9 7 e0003883 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Janna M Schurer Ellen Rafferty Marwa Farag Wu Zeng Emily J Jenkins Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Echinococcosis is a rare but endemic condition in people in Canada, caused by a zoonotic cestode for which the source of human infection is ingestion of parasite eggs shed by canids. The objectives of this study were to identify risk factors associated with infection and to measure the cost-utility of introducing an echinococcosis prevention program in a rural area. We analyzed human case reports submitted to the Canadian Institutes for Health Information between 2002 and 2011. Over this 10 year period, there were 48 cases associated with E. granulosus/E. canadensis, 16 with E. multilocularis, and 251 cases of echinococcosis for which species was not identified (total 315 cases). Nationally, annual incidence of echinococcosis was 0.14 cases per 100,000 people, which is likely an underestimate due to under-diagnosis and under-reporting. Risk factors for echinococcosis included female gender, age (>65 years), and residing in one of the northern territories (Nunavut, Yukon, or Northwest Territories). The average cost of treating a case of cystic echinococcosis in Canada was $8,842 CAD. Cost-utility analysis revealed that dosing dogs with praziquantel (a cestocide) at six week intervals to control cystic echinococcosis is not currently cost-effective at a threshold of $20,000-100,000 per Quality Adjusted Life Year (QALY) gained, even in a health region with the highest incidence rate in Canada ($666,978-755,051 per QALY gained). However, threshold analysis demonstrated that the program may become cost-saving at an echinococcosis incidence of 13-85 cases per 100,000 people and therefore, even one additional CE case in a community of 9000 people could result in the monetary benefits of the program outweighing costs. |
format |
Article in Journal/Newspaper |
author |
Janna M Schurer Ellen Rafferty Marwa Farag Wu Zeng Emily J Jenkins |
author_facet |
Janna M Schurer Ellen Rafferty Marwa Farag Wu Zeng Emily J Jenkins |
author_sort |
Janna M Schurer |
title |
Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada. |
title_short |
Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada. |
title_full |
Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada. |
title_fullStr |
Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada. |
title_full_unstemmed |
Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada. |
title_sort |
echinococcosis: an economic evaluation of a veterinary public health intervention in rural canada. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2015 |
url |
https://doi.org/10.1371/journal.pntd.0003883 https://doaj.org/article/39c5b03cd2184d38ac5982ab6bbd3d33 |
geographic |
Arctic Nunavut Yukon Northwest Territories Canada |
geographic_facet |
Arctic Nunavut Yukon Northwest Territories Canada |
genre |
Arctic Northwest Territories Nunavut Yukon |
genre_facet |
Arctic Northwest Territories Nunavut Yukon |
op_source |
PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003883 (2015) |
op_relation |
http://europepmc.org/articles/PMC4489623?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003883 https://doaj.org/article/39c5b03cd2184d38ac5982ab6bbd3d33 |
op_doi |
https://doi.org/10.1371/journal.pntd.0003883 |
container_title |
PLOS Neglected Tropical Diseases |
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9 |
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7 |
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e0003883 |
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1766343492885282816 |