The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos.
INTRODUCTION:Laos has the highest maternal mortality ratio in mainland Southeast Asia and a high incidence of infectious diseases. Globally, malaria has been the pathogen most intensively investigated in relation to impact on pregnancy, but there has been relatively little research on the aetiology...
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ftdoajarticles:oai:doaj.org/article:382f775c3657445fa80983ff29e00164 2023-05-15T15:16:08+02:00 The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. Vilada Chansamouth Syvilay Thammasack Rattanaphone Phetsouvanh Valy Keoluangkot Catrin E Moore Stuart D Blacksell Josee Castonguay-Vanier Audrey Dubot-Pérès Jarasporn Tangkhabuanbutra Narongchai Tongyoo Phooksavanh Souphaphonh Onanong Sengvilaipaseuth Manivanh Vongsouvath Koukeo Phommasone Davanh Sengdethka Amphayvanh Seurbsanith Scott B Craig Laura Hermann Michel Strobel Paul N Newton 2016-04-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004577 https://doaj.org/article/382f775c3657445fa80983ff29e00164 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4822858?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004577 https://doaj.org/article/382f775c3657445fa80983ff29e00164 PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004577 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004577 2022-12-31T01:28:59Z INTRODUCTION:Laos has the highest maternal mortality ratio in mainland Southeast Asia and a high incidence of infectious diseases. Globally, malaria has been the pathogen most intensively investigated in relation to impact on pregnancy, but there has been relatively little research on the aetiology and impact of other diseases. We therefore aimed to determine the causes and impact of fever in pregnant women admitted to two central hospitals in Vientiane City, Lao PDR (Laos). MATERIALS AND METHODS:This hospital-based prospective study was conducted in Mahosot Hospital and the Mother and Child Hospital, Vientiane, between 2006 and 2010, with the aim to recruit 250 consenting pregnant women admitted with tympanic temperature ≥37.5°C. Primary outcome was the cause of fever and secondary outcomes were pregnancy outcomes. Specific investigations (culture, antigen, molecular and serological tests) were performed to investigate causes of fever. After discharge, all pregnant women were asked to return for review and convalescence serum on day 10-14 and were monitored until delivery. PRINCIPLE FINDINGS:250 pregnant women were recruited to this study between February 2006 and November 2010. Fifty percent were pregnant for the first time. Their median (range) gestational age on admission was 24 (4-43) weeks. The median (range) tympanic admission temperature was 38.5°C (37.5-40.5°C). Fifteen percent of patients stated that they had taken antibiotics before admission. Headache, myalgia, back pain and arthralgia were described by >60% of patients and 149 (60%) were given a laboratory diagnosis. Of those with confirmed diagnoses, 132 (53%) had a single disease and 17 (7%) had apparent mixed diseases. Among those who had a single disease, dengue fever was the most common diagnosis, followed by pyelonephritis, scrub typhus, murine typhus and typhoid. Patients were also diagnosed with tuberculosis, appendicitis, Staphylococcus aureus septicemia, leptospirosis, Japanese encephalitis virus infection and Plasmodium falciparum ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 4 e0004577 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Vilada Chansamouth Syvilay Thammasack Rattanaphone Phetsouvanh Valy Keoluangkot Catrin E Moore Stuart D Blacksell Josee Castonguay-Vanier Audrey Dubot-Pérès Jarasporn Tangkhabuanbutra Narongchai Tongyoo Phooksavanh Souphaphonh Onanong Sengvilaipaseuth Manivanh Vongsouvath Koukeo Phommasone Davanh Sengdethka Amphayvanh Seurbsanith Scott B Craig Laura Hermann Michel Strobel Paul N Newton The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
INTRODUCTION:Laos has the highest maternal mortality ratio in mainland Southeast Asia and a high incidence of infectious diseases. Globally, malaria has been the pathogen most intensively investigated in relation to impact on pregnancy, but there has been relatively little research on the aetiology and impact of other diseases. We therefore aimed to determine the causes and impact of fever in pregnant women admitted to two central hospitals in Vientiane City, Lao PDR (Laos). MATERIALS AND METHODS:This hospital-based prospective study was conducted in Mahosot Hospital and the Mother and Child Hospital, Vientiane, between 2006 and 2010, with the aim to recruit 250 consenting pregnant women admitted with tympanic temperature ≥37.5°C. Primary outcome was the cause of fever and secondary outcomes were pregnancy outcomes. Specific investigations (culture, antigen, molecular and serological tests) were performed to investigate causes of fever. After discharge, all pregnant women were asked to return for review and convalescence serum on day 10-14 and were monitored until delivery. PRINCIPLE FINDINGS:250 pregnant women were recruited to this study between February 2006 and November 2010. Fifty percent were pregnant for the first time. Their median (range) gestational age on admission was 24 (4-43) weeks. The median (range) tympanic admission temperature was 38.5°C (37.5-40.5°C). Fifteen percent of patients stated that they had taken antibiotics before admission. Headache, myalgia, back pain and arthralgia were described by >60% of patients and 149 (60%) were given a laboratory diagnosis. Of those with confirmed diagnoses, 132 (53%) had a single disease and 17 (7%) had apparent mixed diseases. Among those who had a single disease, dengue fever was the most common diagnosis, followed by pyelonephritis, scrub typhus, murine typhus and typhoid. Patients were also diagnosed with tuberculosis, appendicitis, Staphylococcus aureus septicemia, leptospirosis, Japanese encephalitis virus infection and Plasmodium falciparum ... |
format |
Article in Journal/Newspaper |
author |
Vilada Chansamouth Syvilay Thammasack Rattanaphone Phetsouvanh Valy Keoluangkot Catrin E Moore Stuart D Blacksell Josee Castonguay-Vanier Audrey Dubot-Pérès Jarasporn Tangkhabuanbutra Narongchai Tongyoo Phooksavanh Souphaphonh Onanong Sengvilaipaseuth Manivanh Vongsouvath Koukeo Phommasone Davanh Sengdethka Amphayvanh Seurbsanith Scott B Craig Laura Hermann Michel Strobel Paul N Newton |
author_facet |
Vilada Chansamouth Syvilay Thammasack Rattanaphone Phetsouvanh Valy Keoluangkot Catrin E Moore Stuart D Blacksell Josee Castonguay-Vanier Audrey Dubot-Pérès Jarasporn Tangkhabuanbutra Narongchai Tongyoo Phooksavanh Souphaphonh Onanong Sengvilaipaseuth Manivanh Vongsouvath Koukeo Phommasone Davanh Sengdethka Amphayvanh Seurbsanith Scott B Craig Laura Hermann Michel Strobel Paul N Newton |
author_sort |
Vilada Chansamouth |
title |
The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. |
title_short |
The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. |
title_full |
The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. |
title_fullStr |
The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. |
title_full_unstemmed |
The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. |
title_sort |
aetiologies and impact of fever in pregnant inpatients in vientiane, laos. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0004577 https://doaj.org/article/382f775c3657445fa80983ff29e00164 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004577 (2016) |
op_relation |
http://europepmc.org/articles/PMC4822858?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004577 https://doaj.org/article/382f775c3657445fa80983ff29e00164 |
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https://doi.org/10.1371/journal.pntd.0004577 |
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PLOS Neglected Tropical Diseases |
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