Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016.
Madariaga virus (MADV), also known as South American eastern equine encephalitis virus, has been identified in animals and humans in South and Central America, but not previously in Hispaniola or the northern Caribbean. MADV was isolated from virus cultures of plasma from an 8-year-old child in a sc...
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ftdoajarticles:oai:doaj.org/article:382823990cc540cab2ee9383926fff59 2023-05-15T15:05:00+02:00 Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016. John A Lednicky Sarah K White Carla N Mavian Maha A El Badry Taina Telisma Marco Salemi Bernard A OKech V Madsen Beau De Rochars J Glenn Morris 2019-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0006972 https://doaj.org/article/382823990cc540cab2ee9383926fff59 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0006972 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006972 https://doaj.org/article/382823990cc540cab2ee9383926fff59 PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0006972 (2019) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1371/journal.pntd.0006972 2022-12-31T13:13:19Z Madariaga virus (MADV), also known as South American eastern equine encephalitis virus, has been identified in animals and humans in South and Central America, but not previously in Hispaniola or the northern Caribbean. MADV was isolated from virus cultures of plasma from an 8-year-old child in a school cohort in the Gressier/Leogane region of Haiti, who was seen in April, 2015, with acute febrile illness (AFI). The virus was subsequently cultured from an additional seven AFI case patients from this same cohort in February, April, and May 2016. Symptoms most closely resembled those seen with confirmed dengue virus infection. Sequence data were available for four isolates: all were within the same clade, with phylogenetic and molecular clock data suggesting recent introduction of the virus into Haiti from Panama sometime in the period from October 2012-January 2015. Our data document the movement of MADV into Haiti, and raise questions about the potential for further spread in the Caribbean or North America. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Madariaga ENVELOPE(-61.272,-61.272,-64.048,-64.048) PLOS Neglected Tropical Diseases 13 1 e0006972 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 John A Lednicky Sarah K White Carla N Mavian Maha A El Badry Taina Telisma Marco Salemi Bernard A OKech V Madsen Beau De Rochars J Glenn Morris Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Madariaga virus (MADV), also known as South American eastern equine encephalitis virus, has been identified in animals and humans in South and Central America, but not previously in Hispaniola or the northern Caribbean. MADV was isolated from virus cultures of plasma from an 8-year-old child in a school cohort in the Gressier/Leogane region of Haiti, who was seen in April, 2015, with acute febrile illness (AFI). The virus was subsequently cultured from an additional seven AFI case patients from this same cohort in February, April, and May 2016. Symptoms most closely resembled those seen with confirmed dengue virus infection. Sequence data were available for four isolates: all were within the same clade, with phylogenetic and molecular clock data suggesting recent introduction of the virus into Haiti from Panama sometime in the period from October 2012-January 2015. Our data document the movement of MADV into Haiti, and raise questions about the potential for further spread in the Caribbean or North America. |
format |
Article in Journal/Newspaper |
author |
John A Lednicky Sarah K White Carla N Mavian Maha A El Badry Taina Telisma Marco Salemi Bernard A OKech V Madsen Beau De Rochars J Glenn Morris |
author_facet |
John A Lednicky Sarah K White Carla N Mavian Maha A El Badry Taina Telisma Marco Salemi Bernard A OKech V Madsen Beau De Rochars J Glenn Morris |
author_sort |
John A Lednicky |
title |
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016. |
title_short |
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016. |
title_full |
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016. |
title_fullStr |
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016. |
title_full_unstemmed |
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016. |
title_sort |
emergence of madariaga virus as a cause of acute febrile illness in children, haiti, 2015-2016. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2019 |
url |
https://doi.org/10.1371/journal.pntd.0006972 https://doaj.org/article/382823990cc540cab2ee9383926fff59 |
long_lat |
ENVELOPE(-61.272,-61.272,-64.048,-64.048) |
geographic |
Arctic Madariaga |
geographic_facet |
Arctic Madariaga |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0006972 (2019) |
op_relation |
https://doi.org/10.1371/journal.pntd.0006972 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006972 https://doaj.org/article/382823990cc540cab2ee9383926fff59 |
op_doi |
https://doi.org/10.1371/journal.pntd.0006972 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
13 |
container_issue |
1 |
container_start_page |
e0006972 |
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1766336773450891264 |