Multiomics Provide Insights into the Key Molecules and Pathways Involved in the Physiological Adaptation of Atlantic Salmon ( Salmo salar ) to Chemotherapeutic-Induced Oxidative Stress

• Published in: Antioxidants
• Main Authors: Carlo C. Lazado, Gerrit Timmerhaus, Mette W. Breiland, Karin Pittman, Sigurd Hytterød
• Format: Article in Journal/Newspaper
• Language: English
• Published: MDPI AG 2021
• Subjects: aquaculture; amoebic gill disease; disinfection; mucosal immunity; oxidative stress; Therapeutics. Pharmacology; RM1-950; Paa; Atlantic salmon; Salmo salar
• Online Access: https://doi.org/10.3390/antiox10121931; https://doaj.org/article/382230b2f34e433cb5ac57f03874c2fb

Although chemotherapeutics are used to treat infections in farmed fish, knowledge on how they alter host physiology is limited. Here, we elucidated the physiological consequences of repeated exposure to the potent oxidative chemotherapeutic peracetic acid (PAA) in Atlantic salmon ( Salmo salar ) smo...