Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes.
The planorbid gastropod genus Bulinus consists of 38 species that vary in their ability to vector Schistosoma haematobium (the causative agent of human urogenital schistosomiasis), other Schistosoma species, and non-schistosome trematodes. Relying on sequence-based identifications of bulinids (parti...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0010752 https://doaj.org/article/37f3bf13bfb24faba294dabcc067fe1d |
id |
ftdoajarticles:oai:doaj.org/article:37f3bf13bfb24faba294dabcc067fe1d |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:37f3bf13bfb24faba294dabcc067fe1d 2023-05-15T15:16:14+02:00 Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes. Caitlin R Babbitt Martina R Laidemitt Martin W Mutuku Polycup O Oraro Sara V Brant Gerald M Mkoji Eric S Loker 2023-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0010752 https://doaj.org/article/37f3bf13bfb24faba294dabcc067fe1d EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0010752 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010752 https://doaj.org/article/37f3bf13bfb24faba294dabcc067fe1d PLoS Neglected Tropical Diseases, Vol 17, Iss 2, p e0010752 (2023) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles https://doi.org/10.1371/journal.pntd.0010752 2023-03-19T01:32:04Z The planorbid gastropod genus Bulinus consists of 38 species that vary in their ability to vector Schistosoma haematobium (the causative agent of human urogenital schistosomiasis), other Schistosoma species, and non-schistosome trematodes. Relying on sequence-based identifications of bulinids (partial cox1 and 16S) and Schistosoma (cox1 and ITS), we examined Bulinus species in the Lake Victoria Basin in Kenya for naturally acquired infections with Schistosoma species. We collected 6,133 bulinids from 11 sites between 2014-2021, 226 (3.7%) of which harbored Schistosoma infections. We found 4 Bulinus taxa from Lake Victoria (B. truncatus, B. tropicus, B. ugandae, and B. cf. transversalis), and an additional 4 from other habitats (B. globosus, B. productus, B. forskalii, and B. scalaris). S. haematobium infections were found in B. globosus and B. productus (with infections in the former predominating) whereas S. bovis infections were identified in B. globosus, B. productus, B. forskalii, and B. ugandae. No nuclear/mitochondrial discordance potentially indicative of S. haematobium/S. bovis hybridization was detected. We highlight the presence of Bulinus ugandae as a distinct lake-dwelling taxon closely related to B. globosus yet, unlike all other members of the B. africanus species group, is likely not a vector for S. haematobium, though it does exhibit susceptibility to S. bovis. Other lake-dwelling bulinids also lacked S. haematobium infections, supporting the possibility that they all lack compatibility with local S. haematobium, thereby preventing widespread transmission of urogenital schistosomiasis in the lake's waters. We support B. productus as a distinct species from B. nasutus, B. scalaris as distinct from B. forskalii, and add further evidence for a B. globosus species complex with three lineages represented in Kenya alone. This study serves as an essential prelude for investigating why these patterns in compatibility exist and whether the underlying biological mechanisms may be exploited for the purpose ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 17 2 e0010752 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Caitlin R Babbitt Martina R Laidemitt Martin W Mutuku Polycup O Oraro Sara V Brant Gerald M Mkoji Eric S Loker Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
The planorbid gastropod genus Bulinus consists of 38 species that vary in their ability to vector Schistosoma haematobium (the causative agent of human urogenital schistosomiasis), other Schistosoma species, and non-schistosome trematodes. Relying on sequence-based identifications of bulinids (partial cox1 and 16S) and Schistosoma (cox1 and ITS), we examined Bulinus species in the Lake Victoria Basin in Kenya for naturally acquired infections with Schistosoma species. We collected 6,133 bulinids from 11 sites between 2014-2021, 226 (3.7%) of which harbored Schistosoma infections. We found 4 Bulinus taxa from Lake Victoria (B. truncatus, B. tropicus, B. ugandae, and B. cf. transversalis), and an additional 4 from other habitats (B. globosus, B. productus, B. forskalii, and B. scalaris). S. haematobium infections were found in B. globosus and B. productus (with infections in the former predominating) whereas S. bovis infections were identified in B. globosus, B. productus, B. forskalii, and B. ugandae. No nuclear/mitochondrial discordance potentially indicative of S. haematobium/S. bovis hybridization was detected. We highlight the presence of Bulinus ugandae as a distinct lake-dwelling taxon closely related to B. globosus yet, unlike all other members of the B. africanus species group, is likely not a vector for S. haematobium, though it does exhibit susceptibility to S. bovis. Other lake-dwelling bulinids also lacked S. haematobium infections, supporting the possibility that they all lack compatibility with local S. haematobium, thereby preventing widespread transmission of urogenital schistosomiasis in the lake's waters. We support B. productus as a distinct species from B. nasutus, B. scalaris as distinct from B. forskalii, and add further evidence for a B. globosus species complex with three lineages represented in Kenya alone. This study serves as an essential prelude for investigating why these patterns in compatibility exist and whether the underlying biological mechanisms may be exploited for the purpose ... |
format |
Article in Journal/Newspaper |
author |
Caitlin R Babbitt Martina R Laidemitt Martin W Mutuku Polycup O Oraro Sara V Brant Gerald M Mkoji Eric S Loker |
author_facet |
Caitlin R Babbitt Martina R Laidemitt Martin W Mutuku Polycup O Oraro Sara V Brant Gerald M Mkoji Eric S Loker |
author_sort |
Caitlin R Babbitt |
title |
Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes. |
title_short |
Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes. |
title_full |
Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes. |
title_fullStr |
Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes. |
title_full_unstemmed |
Bulinus snails in the Lake Victoria Basin in Kenya: Systematics and their role as hosts for schistosomes. |
title_sort |
bulinus snails in the lake victoria basin in kenya: systematics and their role as hosts for schistosomes. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2023 |
url |
https://doi.org/10.1371/journal.pntd.0010752 https://doaj.org/article/37f3bf13bfb24faba294dabcc067fe1d |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 17, Iss 2, p e0010752 (2023) |
op_relation |
https://doi.org/10.1371/journal.pntd.0010752 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010752 https://doaj.org/article/37f3bf13bfb24faba294dabcc067fe1d |
op_doi |
https://doi.org/10.1371/journal.pntd.0010752 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
17 |
container_issue |
2 |
container_start_page |
e0010752 |
_version_ |
1766346520189206528 |