Systemic lupus erythematosus associated with sickle-cell disease: a case report and literature review

• Published in: Journal of Medical Case Reports
• Main Authors: Maamar Mouna, Tazi-Mezalek Zoubida, Harmouche Hicham, Mounfaloti Wafaa, Adnaoui Mohammed, Aouni Mohammed
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2012
• Subjects: Sickle-cell disease; systemic lupus erythematosus; Medicine; R; Sickle; The Pointers
• Online Access: https://doi.org/10.1186/1752-1947-6-366; https://doaj.org/article/36ca2312d26f4a0e9bae7e2bee02a68f

Abstract Introduction The occurrence of systemic lupus erythematosus has been only rarely reported in patients with sickle-cell disease. Case presentation We describe the case of a 23-year-old North-African woman with sickle-cell disease and systemic lupus erythematosus, and discuss the pointers to the diagnosis of this combination of conditions and also present a review of literature. The diagnosis of systemic lupus erythematosus was delayed because our patient’s symptoms were initially attributed to sickle-cell disease. Conclusions Physicians should be alerted to the possible association of sickle-cell disease and systemic lupus erythematosus so as not to delay correct diagnosis and initiation of appropriate treatment.