N-acylation of ethanolamine using lipase: a chemoselective catalyst
The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid suppor...
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ftdoajarticles:oai:doaj.org/article:36c7664839a94460ad287faf6e80a96c 2023-05-15T13:37:15+02:00 N-acylation of ethanolamine using lipase: a chemoselective catalyst Mazaahir Kidwai Roona Poddar Poonam Mothsra 2009-03-01T00:00:00Z https://doi.org/10.3762/bjoc.5.10 https://doaj.org/article/36c7664839a94460ad287faf6e80a96c EN eng Beilstein-Institut https://doi.org/10.3762/bjoc.5.10 https://doaj.org/toc/1860-5397 1860-5397 doi:10.3762/bjoc.5.10 https://doaj.org/article/36c7664839a94460ad287faf6e80a96c Beilstein Journal of Organic Chemistry, Vol 5, Iss 1, p 10 (2009) chemoselective lipase microwave irradiation zein number Science Q Organic chemistry QD241-441 article 2009 ftdoajarticles https://doi.org/10.3762/bjoc.5.10 2022-12-31T06:20:37Z The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and results were compared. There is a synergy between the enzyme catalysis and microwave irradiation. Article in Journal/Newspaper Antarc* Antarctica Directory of Open Access Journals: DOAJ Articles Beilstein Journal of Organic Chemistry 5 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
chemoselective lipase microwave irradiation zein number Science Q Organic chemistry QD241-441 |
spellingShingle |
chemoselective lipase microwave irradiation zein number Science Q Organic chemistry QD241-441 Mazaahir Kidwai Roona Poddar Poonam Mothsra N-acylation of ethanolamine using lipase: a chemoselective catalyst |
topic_facet |
chemoselective lipase microwave irradiation zein number Science Q Organic chemistry QD241-441 |
description |
The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and results were compared. There is a synergy between the enzyme catalysis and microwave irradiation. |
format |
Article in Journal/Newspaper |
author |
Mazaahir Kidwai Roona Poddar Poonam Mothsra |
author_facet |
Mazaahir Kidwai Roona Poddar Poonam Mothsra |
author_sort |
Mazaahir Kidwai |
title |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_short |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_full |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_fullStr |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_full_unstemmed |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_sort |
n-acylation of ethanolamine using lipase: a chemoselective catalyst |
publisher |
Beilstein-Institut |
publishDate |
2009 |
url |
https://doi.org/10.3762/bjoc.5.10 https://doaj.org/article/36c7664839a94460ad287faf6e80a96c |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Beilstein Journal of Organic Chemistry, Vol 5, Iss 1, p 10 (2009) |
op_relation |
https://doi.org/10.3762/bjoc.5.10 https://doaj.org/toc/1860-5397 1860-5397 doi:10.3762/bjoc.5.10 https://doaj.org/article/36c7664839a94460ad287faf6e80a96c |
op_doi |
https://doi.org/10.3762/bjoc.5.10 |
container_title |
Beilstein Journal of Organic Chemistry |
container_volume |
5 |
_version_ |
1766089747030081536 |