N-acylation of ethanolamine using lipase: a chemoselective catalyst

The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid suppor...

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Bibliographic Details
Published in:Beilstein Journal of Organic Chemistry
Main Authors: Mazaahir Kidwai, Roona Poddar, Poonam Mothsra
Format: Article in Journal/Newspaper
Language:English
Published: Beilstein-Institut 2009
Subjects:
chemoselective
lipase
microwave irradiation
zein number
Science
Q
Organic chemistry
QD241-441
Antarc*
Antarctica
Online Access:https://doi.org/10.3762/bjoc.5.10
https://doaj.org/article/36c7664839a94460ad287faf6e80a96c
id ftdoajarticles:oai:doaj.org/article:36c7664839a94460ad287faf6e80a96c
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spelling ftdoajarticles:oai:doaj.org/article:36c7664839a94460ad287faf6e80a96c 2023-05-15T13:37:15+02:00 N-acylation of ethanolamine using lipase: a chemoselective catalyst Mazaahir Kidwai Roona Poddar Poonam Mothsra 2009-03-01T00:00:00Z https://doi.org/10.3762/bjoc.5.10 https://doaj.org/article/36c7664839a94460ad287faf6e80a96c EN eng Beilstein-Institut https://doi.org/10.3762/bjoc.5.10 https://doaj.org/toc/1860-5397 1860-5397 doi:10.3762/bjoc.5.10 https://doaj.org/article/36c7664839a94460ad287faf6e80a96c Beilstein Journal of Organic Chemistry, Vol 5, Iss 1, p 10 (2009) chemoselective lipase microwave irradiation zein number Science Q Organic chemistry QD241-441 article 2009 ftdoajarticles https://doi.org/10.3762/bjoc.5.10 2022-12-31T06:20:37Z The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and results were compared. There is a synergy between the enzyme catalysis and microwave irradiation. Article in Journal/Newspaper Antarc* Antarctica Directory of Open Access Journals: DOAJ Articles Beilstein Journal of Organic Chemistry 5
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic chemoselective
lipase
microwave irradiation
zein number
Science
Q
Organic chemistry
QD241-441
spellingShingle chemoselective
lipase
microwave irradiation
zein number
Science
Q
Organic chemistry
QD241-441
Mazaahir Kidwai
Roona Poddar
Poonam Mothsra
N-acylation of ethanolamine using lipase: a chemoselective catalyst
topic_facet chemoselective
lipase
microwave irradiation
zein number
Science
Q
Organic chemistry
QD241-441
description The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and results were compared. There is a synergy between the enzyme catalysis and microwave irradiation.
format Article in Journal/Newspaper
author Mazaahir Kidwai
Roona Poddar
Poonam Mothsra
author_facet Mazaahir Kidwai
Roona Poddar
Poonam Mothsra
author_sort Mazaahir Kidwai
title N-acylation of ethanolamine using lipase: a chemoselective catalyst
title_short N-acylation of ethanolamine using lipase: a chemoselective catalyst
title_full N-acylation of ethanolamine using lipase: a chemoselective catalyst
title_fullStr N-acylation of ethanolamine using lipase: a chemoselective catalyst
title_full_unstemmed N-acylation of ethanolamine using lipase: a chemoselective catalyst
title_sort n-acylation of ethanolamine using lipase: a chemoselective catalyst
publisher Beilstein-Institut
publishDate 2009
url https://doi.org/10.3762/bjoc.5.10
https://doaj.org/article/36c7664839a94460ad287faf6e80a96c
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_source Beilstein Journal of Organic Chemistry, Vol 5, Iss 1, p 10 (2009)
op_relation https://doi.org/10.3762/bjoc.5.10
https://doaj.org/toc/1860-5397
1860-5397
doi:10.3762/bjoc.5.10
https://doaj.org/article/36c7664839a94460ad287faf6e80a96c
op_doi https://doi.org/10.3762/bjoc.5.10
container_title Beilstein Journal of Organic Chemistry
container_volume 5
_version_ 1766089747030081536

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