Articulating ethical principles guiding Target Malaria's engagement strategy
Abstract Progress in gene drive research has engendered a lively discussion about community engagement and the ethical standards the work hinges on. While there is broad agreement regarding ethical principles and established best practices for conducting clinical public health research, projects dev...
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ftdoajarticles:oai:doaj.org/article:365159c7ad40423a8a2438b669798eae 2023-05-15T15:13:39+02:00 Articulating ethical principles guiding Target Malaria's engagement strategy Aaron J. Roberts Delphine Thizy 2022-02-01T00:00:00Z https://doi.org/10.1186/s12936-022-04062-4 https://doaj.org/article/365159c7ad40423a8a2438b669798eae EN eng BMC https://doi.org/10.1186/s12936-022-04062-4 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04062-4 1475-2875 https://doaj.org/article/365159c7ad40423a8a2438b669798eae Malaria Journal, Vol 21, Iss 1, Pp 1-11 (2022) Ethics Stakeholder engagement Gene drive Vector control Malaria Responsible research Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2022 ftdoajarticles https://doi.org/10.1186/s12936-022-04062-4 2022-12-31T14:40:16Z Abstract Progress in gene drive research has engendered a lively discussion about community engagement and the ethical standards the work hinges on. While there is broad agreement regarding ethical principles and established best practices for conducting clinical public health research, projects developing area-wide vector control technologies and initiating ambitious engagement strategies raise specific questions: who to engage, when to engage, and how? When responding to these fundamental questions, with few best practices available for guidance, projects need to reflect on and articulate the ethical principles that motivate and justify their approach. Target Malaria is a not-for-profit research consortium that aims to develop and share malaria control and elimination technology. The consortium is currently investigating the potential of a genetic technique called gene drive to control populations of malaria vectoring mosquito species Anopheles gambiae. Due to the potentially broad geographical, environmental impact of gene drive technology, Target Malaria has committed to a robust form of tailored engagement with the local communities in Burkina Faso, Mali, and Uganda, where research activities are currently taking place. This paper presents the principles guiding Target Malaria’s engagement strategy. Herein the authors (i) articulate the principles; (ii) explain the rationale for selecting them; (iii) share early lessons about the application of the principles. Since gene drive technology is an emerging technology, with few best practices available for guidance, the authors hope by sharing these lessons, to add to the growing literature regarding engagement strategies and practices for area-wide vector control, and more specifically, for gene drive research. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 21 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Ethics Stakeholder engagement Gene drive Vector control Malaria Responsible research Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Ethics Stakeholder engagement Gene drive Vector control Malaria Responsible research Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Aaron J. Roberts Delphine Thizy Articulating ethical principles guiding Target Malaria's engagement strategy |
topic_facet |
Ethics Stakeholder engagement Gene drive Vector control Malaria Responsible research Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Progress in gene drive research has engendered a lively discussion about community engagement and the ethical standards the work hinges on. While there is broad agreement regarding ethical principles and established best practices for conducting clinical public health research, projects developing area-wide vector control technologies and initiating ambitious engagement strategies raise specific questions: who to engage, when to engage, and how? When responding to these fundamental questions, with few best practices available for guidance, projects need to reflect on and articulate the ethical principles that motivate and justify their approach. Target Malaria is a not-for-profit research consortium that aims to develop and share malaria control and elimination technology. The consortium is currently investigating the potential of a genetic technique called gene drive to control populations of malaria vectoring mosquito species Anopheles gambiae. Due to the potentially broad geographical, environmental impact of gene drive technology, Target Malaria has committed to a robust form of tailored engagement with the local communities in Burkina Faso, Mali, and Uganda, where research activities are currently taking place. This paper presents the principles guiding Target Malaria’s engagement strategy. Herein the authors (i) articulate the principles; (ii) explain the rationale for selecting them; (iii) share early lessons about the application of the principles. Since gene drive technology is an emerging technology, with few best practices available for guidance, the authors hope by sharing these lessons, to add to the growing literature regarding engagement strategies and practices for area-wide vector control, and more specifically, for gene drive research. |
format |
Article in Journal/Newspaper |
author |
Aaron J. Roberts Delphine Thizy |
author_facet |
Aaron J. Roberts Delphine Thizy |
author_sort |
Aaron J. Roberts |
title |
Articulating ethical principles guiding Target Malaria's engagement strategy |
title_short |
Articulating ethical principles guiding Target Malaria's engagement strategy |
title_full |
Articulating ethical principles guiding Target Malaria's engagement strategy |
title_fullStr |
Articulating ethical principles guiding Target Malaria's engagement strategy |
title_full_unstemmed |
Articulating ethical principles guiding Target Malaria's engagement strategy |
title_sort |
articulating ethical principles guiding target malaria's engagement strategy |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s12936-022-04062-4 https://doaj.org/article/365159c7ad40423a8a2438b669798eae |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 21, Iss 1, Pp 1-11 (2022) |
op_relation |
https://doi.org/10.1186/s12936-022-04062-4 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04062-4 1475-2875 https://doaj.org/article/365159c7ad40423a8a2438b669798eae |
op_doi |
https://doi.org/10.1186/s12936-022-04062-4 |
container_title |
Malaria Journal |
container_volume |
21 |
container_issue |
1 |
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1766344187015331840 |