Protective immunity by an engineered DNA vaccine for Mayaro virus.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Hyeree Choi, Sagar B Kudchodkar, Emma L Reuschel, Kanika Asija, Piyush Borole, Michelle Ho, Krzysztof Wojtak, Charles Reed, Stephanie Ramos, Nathen E Bopp, Patricia V Aguilar, Scott C Weaver, J Joseph Kim, Laurent Humeau, Pablo Tebas, David B Weiner, Kar Muthumani
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2019
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Trinidad
• Online Access: https://doi.org/10.1371/journal.pntd.0007042; https://doaj.org/article/365111ea733342ab82ae66dc7897d8a4

Mayaro virus (MAYV) of the genus alphavirus is a mosquito-transmitted emerging infectious disease that causes an acute febrile illness, rash, headaches, and nausea that may turn into incapacitating, persistent arthralgias in some victims. Since its discovery in Trinidad in 1954, cases of MAYV infect...