Sexual transmission of human T-cell lymphotropic virus type 1
Human T-cell lymphotropic virus type 1 (HTLV-1) is endemic in many parts of the world and is primarily transmitted through sexual intercourse or from mother to child. Sexual transmission occurs more efficiently from men to women than women to men and might be enhanced by sexually transmitted disease...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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Online Access: | https://doi.org/10.1590/0037-8682-0232-2013 https://doaj.org/article/364eca0cb1f147b0b8622a871c1ecc8d |
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ftdoajarticles:oai:doaj.org/article:364eca0cb1f147b0b8622a871c1ecc8d 2023-05-15T15:07:22+02:00 Sexual transmission of human T-cell lymphotropic virus type 1 Arthur Paiva Jorge Casseb 2014-06-01T00:00:00Z https://doi.org/10.1590/0037-8682-0232-2013 https://doaj.org/article/364eca0cb1f147b0b8622a871c1ecc8d EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300265&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0232-2013 https://doaj.org/article/364eca0cb1f147b0b8622a871c1ecc8d Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 3, Pp 265-274 (2014) Deltaretrovirus Human T-cell lymphotropic virus type 1 Sexually transmitted diseases Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1590/0037-8682-0232-2013 2022-12-31T02:54:53Z Human T-cell lymphotropic virus type 1 (HTLV-1) is endemic in many parts of the world and is primarily transmitted through sexual intercourse or from mother to child. Sexual transmission occurs more efficiently from men to women than women to men and might be enhanced by sexually transmitted diseases that cause ulcers and result in mucosal ruptures, such as syphilis, herpes simplex type 2 (HSV-2), and chancroid. Other sexually transmitted diseases might result in the recruitment of inflammatory cells and could increase the risk of HTLV-1 acquisition and transmission. Additionally, factors that are associated with higher transmission risks include the presence of antibodies against the viral oncoprotein Tax (anti-Tax), a higher proviral load in peripheral blood lymphocytes, and increased cervicovaginal or seminal secretions. Seminal fluid has been reported to increase HTLV replication and transmission, whereas male circumcision and neutralizing antibodies might have a protective effect. Recently, free virions were discovered in plasma, which reveals a possible new mode of HTLV replication. It is unclear how this discovery might affect the routes of HTLV transmission, particularly sexual transmission, because HTLV transmission rates are significantly higher from men to women than women to men. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Circumcision ENVELOPE(-64.167,-64.167,-65.183,-65.183) Revista da Sociedade Brasileira de Medicina Tropical 47 3 265 274 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Deltaretrovirus Human T-cell lymphotropic virus type 1 Sexually transmitted diseases Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Deltaretrovirus Human T-cell lymphotropic virus type 1 Sexually transmitted diseases Arctic medicine. Tropical medicine RC955-962 Arthur Paiva Jorge Casseb Sexual transmission of human T-cell lymphotropic virus type 1 |
topic_facet |
Deltaretrovirus Human T-cell lymphotropic virus type 1 Sexually transmitted diseases Arctic medicine. Tropical medicine RC955-962 |
description |
Human T-cell lymphotropic virus type 1 (HTLV-1) is endemic in many parts of the world and is primarily transmitted through sexual intercourse or from mother to child. Sexual transmission occurs more efficiently from men to women than women to men and might be enhanced by sexually transmitted diseases that cause ulcers and result in mucosal ruptures, such as syphilis, herpes simplex type 2 (HSV-2), and chancroid. Other sexually transmitted diseases might result in the recruitment of inflammatory cells and could increase the risk of HTLV-1 acquisition and transmission. Additionally, factors that are associated with higher transmission risks include the presence of antibodies against the viral oncoprotein Tax (anti-Tax), a higher proviral load in peripheral blood lymphocytes, and increased cervicovaginal or seminal secretions. Seminal fluid has been reported to increase HTLV replication and transmission, whereas male circumcision and neutralizing antibodies might have a protective effect. Recently, free virions were discovered in plasma, which reveals a possible new mode of HTLV replication. It is unclear how this discovery might affect the routes of HTLV transmission, particularly sexual transmission, because HTLV transmission rates are significantly higher from men to women than women to men. |
format |
Article in Journal/Newspaper |
author |
Arthur Paiva Jorge Casseb |
author_facet |
Arthur Paiva Jorge Casseb |
author_sort |
Arthur Paiva |
title |
Sexual transmission of human T-cell lymphotropic virus type 1 |
title_short |
Sexual transmission of human T-cell lymphotropic virus type 1 |
title_full |
Sexual transmission of human T-cell lymphotropic virus type 1 |
title_fullStr |
Sexual transmission of human T-cell lymphotropic virus type 1 |
title_full_unstemmed |
Sexual transmission of human T-cell lymphotropic virus type 1 |
title_sort |
sexual transmission of human t-cell lymphotropic virus type 1 |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2014 |
url |
https://doi.org/10.1590/0037-8682-0232-2013 https://doaj.org/article/364eca0cb1f147b0b8622a871c1ecc8d |
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ENVELOPE(-64.167,-64.167,-65.183,-65.183) |
geographic |
Arctic Circumcision |
geographic_facet |
Arctic Circumcision |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 3, Pp 265-274 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300265&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0232-2013 https://doaj.org/article/364eca0cb1f147b0b8622a871c1ecc8d |
op_doi |
https://doi.org/10.1590/0037-8682-0232-2013 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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47 |
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3 |
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265 |
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274 |
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