Chronic kidney disease among children in Guatemala
OBJECTIVE: To describe the distribution of pediatric chronic kidney disease (CKD) in Guatemala, estimate incidence and prevalence of pediatric end-stage renal disease (ESRD), and estimate time to progress to ESRD. METHODS: This study analyzed the registry of the only pediatric nephrology center in G...
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Pan American Health Organization
2014
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ftdoajarticles:oai:doaj.org/article:35d7d91b08844c14bc23d0e348fb02e0 2023-05-15T15:09:24+02:00 Chronic kidney disease among children in Guatemala Alejandro Cerón Meredith P. Fort Chris M. Morine Randall Lou-Meda 2014-12-01T00:00:00Z https://doaj.org/article/35d7d91b08844c14bc23d0e348fb02e0 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892014001100004&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 https://doaj.org/article/35d7d91b08844c14bc23d0e348fb02e0 Revista Panamericana de Salud Pública, Vol 36, Iss 6, Pp 376-382 (2014) Enfermedades renales fallo renal crónico insuficiencia renal crónica factores de riesgo salud del niño epidemiología Guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles 2022-12-31T00:27:01Z OBJECTIVE: To describe the distribution of pediatric chronic kidney disease (CKD) in Guatemala, estimate incidence and prevalence of pediatric end-stage renal disease (ESRD), and estimate time to progress to ESRD. METHODS: This study analyzed the registry of the only pediatric nephrology center in Guatemala, from 2004-2013. Incidence and prevalence were calculated for annual periods. Moran's index for spatial autocorrelation was used to determine significance of geographic distribution of incidence. Time to progress to ESRD and associated risk factors were calculated with multivariate Cox regression. RESULTS: Of 1 545 patients from birth to less than 20 years of age, 432 had chronic renal failure (CRF). Prevalence and incidence of ESRD were 4.9 and 4.6 per million age-related population, respectively. Incidence was higher for the Pacific coast and Guatemala City. The cause of CRF was undetermined in 43% of patients. Average time to progress to ESRD was 21.9 months; factors associated with progression were: older age, diagnosis of glomerulopathies, and advanced-stage CKD at consultation. CONCLUSIONS: Prevalence and incidence of ESRD in Guatemala are lower than in other countries. This may reflect poor access to diagnosis. Areas with higher incidence and large proportion of CKD of undetermined cause are compatible with other studies from the geographic subregion. Findings on progression to ESRD may reflect delayed referral. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pacific |
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Directory of Open Access Journals: DOAJ Articles |
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English Spanish Portuguese |
topic |
Enfermedades renales fallo renal crónico insuficiencia renal crónica factores de riesgo salud del niño epidemiología Guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Enfermedades renales fallo renal crónico insuficiencia renal crónica factores de riesgo salud del niño epidemiología Guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Alejandro Cerón Meredith P. Fort Chris M. Morine Randall Lou-Meda Chronic kidney disease among children in Guatemala |
topic_facet |
Enfermedades renales fallo renal crónico insuficiencia renal crónica factores de riesgo salud del niño epidemiología Guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
OBJECTIVE: To describe the distribution of pediatric chronic kidney disease (CKD) in Guatemala, estimate incidence and prevalence of pediatric end-stage renal disease (ESRD), and estimate time to progress to ESRD. METHODS: This study analyzed the registry of the only pediatric nephrology center in Guatemala, from 2004-2013. Incidence and prevalence were calculated for annual periods. Moran's index for spatial autocorrelation was used to determine significance of geographic distribution of incidence. Time to progress to ESRD and associated risk factors were calculated with multivariate Cox regression. RESULTS: Of 1 545 patients from birth to less than 20 years of age, 432 had chronic renal failure (CRF). Prevalence and incidence of ESRD were 4.9 and 4.6 per million age-related population, respectively. Incidence was higher for the Pacific coast and Guatemala City. The cause of CRF was undetermined in 43% of patients. Average time to progress to ESRD was 21.9 months; factors associated with progression were: older age, diagnosis of glomerulopathies, and advanced-stage CKD at consultation. CONCLUSIONS: Prevalence and incidence of ESRD in Guatemala are lower than in other countries. This may reflect poor access to diagnosis. Areas with higher incidence and large proportion of CKD of undetermined cause are compatible with other studies from the geographic subregion. Findings on progression to ESRD may reflect delayed referral. |
format |
Article in Journal/Newspaper |
author |
Alejandro Cerón Meredith P. Fort Chris M. Morine Randall Lou-Meda |
author_facet |
Alejandro Cerón Meredith P. Fort Chris M. Morine Randall Lou-Meda |
author_sort |
Alejandro Cerón |
title |
Chronic kidney disease among children in Guatemala |
title_short |
Chronic kidney disease among children in Guatemala |
title_full |
Chronic kidney disease among children in Guatemala |
title_fullStr |
Chronic kidney disease among children in Guatemala |
title_full_unstemmed |
Chronic kidney disease among children in Guatemala |
title_sort |
chronic kidney disease among children in guatemala |
publisher |
Pan American Health Organization |
publishDate |
2014 |
url |
https://doaj.org/article/35d7d91b08844c14bc23d0e348fb02e0 |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 36, Iss 6, Pp 376-382 (2014) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892014001100004&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 https://doaj.org/article/35d7d91b08844c14bc23d0e348fb02e0 |
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1766340599348199424 |