Role of Enterovirus ECHO 30 as the etiological agent of enterovirus infection in the North-West of Russia in 2013

• Main Authors: M. A. Bichurina, N. I. Romanenkova, L. N. Golitsyna, N. R. Rozaeva, O. I. Kanaeva, S. G. Fomina, T. I. Krainova, L. A. Shishko, T. A. Gordienko, V. A. Pianykh, T. G. Ivanova, S. N. Smelkov, M. V. Lesnikova, N. A. Novikova
• Format: Article in Journal/Newspaper
• Language: Russian
• Published: Journal Infectology 2014
• Subjects: энтеровирусная инфекция; выделение и идентификация энтеровирусов; молекулярное типирование; Infectious and parasitic diseases; RC109-216; Arkhangelsk
• Online Access: https://doi.org/10.22625/2072-6732-2014-6-3-84-91; https://doaj.org/article/355c54e85d68426482648b1c9ea9268a

In 2013 after two previous years when the situation had been calm the incidence rates of enterovirus infection significantly increased on certain territories of the North-West of Russia. In Novgorod and Vologda regions and in Saint-Petersburg enterovirus meningitis group cases were registered. The etiology of enterovirus infection was studied by virological and molecular methods. Enterovirus ECHO30 was identified as the principal etiological agent of the cases. Molecular study revealed that enteroviruses ECHO30 isolated in the North-West of Russia belonged to the genotype H and formed two subtypes inside this genotype. Phylogenetic analysis has shown that enteroviruses ECHO30 of both subtypes were closely related to the strains detected in different provinces of China in 2010-2013. Probably enteroviruses ECHO30 of the genotype H which largely circulated in Russia in 2013 and practically had not been detected in the country earlier had been imported on the territory of Russia from South-East Asia. Enteroviruses ECHO30 isolated in Arkhangelsk and Novgorod regions in 2008-2009 belonged to another genotype Ec2. Enteroviruses of this genotype had circulated at that time in the European countries.