Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia.
Despite the increased use of vaccination in several Asian countries, Japanese Encephalitis (JE) remains the most important cause of viral encephalitis in Asia in humans with an estimated 68,000 cases annually. Considered a rural disease occurring mainly in paddy-field dominated landscapes where pigs...
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ftdoajarticles:oai:doaj.org/article:354c9c0b695040d8a91e3cdafc94f843 2023-05-15T15:08:49+02:00 Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia. Julien Cappelle Veasna Duong Long Pring Lida Kong Maud Yakovleff Didot Budi Prasetyo Borin Peng Rithy Choeung Raphaël Duboz Sivuth Ong San Sorn Philippe Dussart Arnaud Tarantola Philippe Buchy Véronique Chevalier 2016-12-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0005149 https://doaj.org/article/354c9c0b695040d8a91e3cdafc94f843 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5142769?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005149 https://doaj.org/article/354c9c0b695040d8a91e3cdafc94f843 PLoS Neglected Tropical Diseases, Vol 10, Iss 12, p e0005149 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0005149 2022-12-30T21:04:29Z Despite the increased use of vaccination in several Asian countries, Japanese Encephalitis (JE) remains the most important cause of viral encephalitis in Asia in humans with an estimated 68,000 cases annually. Considered a rural disease occurring mainly in paddy-field dominated landscapes where pigs are amplifying hosts, JE may nevertheless circulate in a wider range of environment given the diversity of its potential hosts and vectors. The main objective of this study was to assess the intensity of JE transmission to pigs in a peri-urban environment in the outskirt of Phnom Penh, Cambodia. We estimated the force of JE infection in two cohorts of 15 sentinel pigs by fitting a generalised linear model on seroprevalence monitoring data observed during two four-month periods in 2014. Our results provide evidence for intensive circulation of JE virus in a periurban area near Phnom Penh, the capital and most populated city of Cambodia. Understanding JE virus transmission in different environments is important for planning JE virus control in the long term and is also an interesting model to study the complexity of vector-borne diseases. Collecting quantitative data such as the force of infection will help calibrate epidemiological model that can be used to better understand complex vector-borne disease epidemiological cycles. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 12 e0005149 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Julien Cappelle Veasna Duong Long Pring Lida Kong Maud Yakovleff Didot Budi Prasetyo Borin Peng Rithy Choeung Raphaël Duboz Sivuth Ong San Sorn Philippe Dussart Arnaud Tarantola Philippe Buchy Véronique Chevalier Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Despite the increased use of vaccination in several Asian countries, Japanese Encephalitis (JE) remains the most important cause of viral encephalitis in Asia in humans with an estimated 68,000 cases annually. Considered a rural disease occurring mainly in paddy-field dominated landscapes where pigs are amplifying hosts, JE may nevertheless circulate in a wider range of environment given the diversity of its potential hosts and vectors. The main objective of this study was to assess the intensity of JE transmission to pigs in a peri-urban environment in the outskirt of Phnom Penh, Cambodia. We estimated the force of JE infection in two cohorts of 15 sentinel pigs by fitting a generalised linear model on seroprevalence monitoring data observed during two four-month periods in 2014. Our results provide evidence for intensive circulation of JE virus in a periurban area near Phnom Penh, the capital and most populated city of Cambodia. Understanding JE virus transmission in different environments is important for planning JE virus control in the long term and is also an interesting model to study the complexity of vector-borne diseases. Collecting quantitative data such as the force of infection will help calibrate epidemiological model that can be used to better understand complex vector-borne disease epidemiological cycles. |
format |
Article in Journal/Newspaper |
author |
Julien Cappelle Veasna Duong Long Pring Lida Kong Maud Yakovleff Didot Budi Prasetyo Borin Peng Rithy Choeung Raphaël Duboz Sivuth Ong San Sorn Philippe Dussart Arnaud Tarantola Philippe Buchy Véronique Chevalier |
author_facet |
Julien Cappelle Veasna Duong Long Pring Lida Kong Maud Yakovleff Didot Budi Prasetyo Borin Peng Rithy Choeung Raphaël Duboz Sivuth Ong San Sorn Philippe Dussart Arnaud Tarantola Philippe Buchy Véronique Chevalier |
author_sort |
Julien Cappelle |
title |
Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia. |
title_short |
Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia. |
title_full |
Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia. |
title_fullStr |
Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia. |
title_full_unstemmed |
Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia. |
title_sort |
intensive circulation of japanese encephalitis virus in peri-urban sentinel pigs near phnom penh, cambodia. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0005149 https://doaj.org/article/354c9c0b695040d8a91e3cdafc94f843 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 12, p e0005149 (2016) |
op_relation |
http://europepmc.org/articles/PMC5142769?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005149 https://doaj.org/article/354c9c0b695040d8a91e3cdafc94f843 |
op_doi |
https://doi.org/10.1371/journal.pntd.0005149 |
container_title |
PLOS Neglected Tropical Diseases |
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10 |
container_issue |
12 |
container_start_page |
e0005149 |
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1766340111251800064 |