Potential use of Piper nigrum ethanol extract against pyrethroid-resistant Aedes aegypti larvae Utilização em potencial do extrato alcoólico de Piper nigrum como larvicida em Aedes aegypti resistente a piretróides

Fractionation of Piper nigrum ethanol extract, biomonitored by assays on pyrethroid-resistant Aedes aegypti larvae yielded isolation of the larvicidal amides piperolein-A and piperine. Comparing LC50 values, the ethanol extract (0. 98 ppm) was the most toxic, followed by piperolein-A (1. 46ppm) and...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Naomi Kato Simas, Elisangela da Costa Lima, Ricardo Machado Kuster, Celso Luiz Salgueiro Lage, Alfredo Martins de Oliveira Filho
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2007
Subjects:
Piper nigrum
Aedes aegypti
Piperamidas
Larvicida
Piperamides
Larvicide
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.1590/S0037-86822007000400006
https://doaj.org/article/3549e4985d1a4942b1855a48f63657f9
Description
Summary:Fractionation of Piper nigrum ethanol extract, biomonitored by assays on pyrethroid-resistant Aedes aegypti larvae yielded isolation of the larvicidal amides piperolein-A and piperine. Comparing LC50 values, the ethanol extract (0. 98 ppm) was the most toxic, followed by piperolein-A (1. 46ppm) and piperine (1. 53ppm). O fracionamento do extrato etanólico de Piper nigrum biomonitorado por ensaios em larvas de Aedes aegypti resistentes a piretróides resultou no isolamento das amidas larvicidas piperoleína-A e piperina. Comparando-se os valores de CL50, o extrato etanólico (0. 98ppm) foi o mais tóxico, seguido pela piperoleína-A (1. 46ppm) e piperina (1. 53ppm).

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