Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala
Objectives. To determine the prevalence of kidney disease of unknown etiology in banana, melon, and tomato workers in north-eastern Guatemala, and to evaluate the usefulness of a cystatin C blood test for early detection of renal disease. Methods. This was a cross-sectional, farm-based study of 462...
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ftdoajarticles:oai:doaj.org/article:3458207f7cae4328a9df076e76bd2f2c 2023-06-18T03:39:37+02:00 Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala Gerardo Arroyo Gabriella Soto Sofía García Jorge Pérez-Folgar Paola Bailón Brenda Acabal Anita Cocón Mario Díaz-Moscoso Federico Nave 2023-06-01T00:00:00Z https://doi.org/10.26633/RPSP.2023.84 https://doaj.org/article/3458207f7cae4328a9df076e76bd2f2c EN ES PT eng spa por Pan American Health Organization https://iris.paho.org/handle/10665.2/57548 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2023.84 https://doaj.org/article/3458207f7cae4328a9df076e76bd2f2c Revista Panamericana de Salud Pública, Vol 47, Iss 84, Pp 1-9 (2023) kidney diseases farm workers glomerular filtration rate guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles https://doi.org/10.26633/RPSP.2023.84 2023-06-04T00:37:18Z Objectives. To determine the prevalence of kidney disease of unknown etiology in banana, melon, and tomato workers in north-eastern Guatemala, and to evaluate the usefulness of a cystatin C blood test for early detection of renal disease. Methods. This was a cross-sectional, farm-based study of 462 agricultural workers conducted from June to September 2021. Epidemiological and demographic characteristics of the workers were collected through a self-administered questionnaire. Blood samples were obtained to determine glucose, creatinine and cystatin C levels. Anthropometric and clinical data were also recorded. Results. The prevalence of kidney disease of unknown etiology was 3.03% (95% confidence interval (CI): 1.36–4.70%) based on glomerular filtration rate (GFR-EPI) < 60 mL/min/1.73 m2, with a significantly higher prevalence in banana workers (5.67%; 95% CI: 2.16–9.18%) than melon workers (p = 0.009) and tomato workers (p = 0.044). Ten workers (2.16%) had reduced kidney function (GFR-EPI 60–90 mL/min/1.73 m2). The levels of cystatin C showed less variability (coefficient of variation 46.4%) than those of creatinine (coefficient of variation 67.0%), and cystatin C levels in cases with abnormal and reduced kidney function were significantly different from cases with normal kidney function (p < 0.001). Conclusions. Surveillance of the health of active farm workers and improvement of working conditions, such as sun protection, adequate hydration, and sufficient breaks, are recommended. The significant differences in cystatin C levels between cases with abnormal and reduced kidney function and those with normal kidney function suggest that cystatin C could be a useful measure for early detection of renal disease. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista Panamericana de Salud Pública 47 1 |
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English Spanish Portuguese |
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kidney diseases farm workers glomerular filtration rate guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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kidney diseases farm workers glomerular filtration rate guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Gerardo Arroyo Gabriella Soto Sofía García Jorge Pérez-Folgar Paola Bailón Brenda Acabal Anita Cocón Mario Díaz-Moscoso Federico Nave Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala |
topic_facet |
kidney diseases farm workers glomerular filtration rate guatemala Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Objectives. To determine the prevalence of kidney disease of unknown etiology in banana, melon, and tomato workers in north-eastern Guatemala, and to evaluate the usefulness of a cystatin C blood test for early detection of renal disease. Methods. This was a cross-sectional, farm-based study of 462 agricultural workers conducted from June to September 2021. Epidemiological and demographic characteristics of the workers were collected through a self-administered questionnaire. Blood samples were obtained to determine glucose, creatinine and cystatin C levels. Anthropometric and clinical data were also recorded. Results. The prevalence of kidney disease of unknown etiology was 3.03% (95% confidence interval (CI): 1.36–4.70%) based on glomerular filtration rate (GFR-EPI) < 60 mL/min/1.73 m2, with a significantly higher prevalence in banana workers (5.67%; 95% CI: 2.16–9.18%) than melon workers (p = 0.009) and tomato workers (p = 0.044). Ten workers (2.16%) had reduced kidney function (GFR-EPI 60–90 mL/min/1.73 m2). The levels of cystatin C showed less variability (coefficient of variation 46.4%) than those of creatinine (coefficient of variation 67.0%), and cystatin C levels in cases with abnormal and reduced kidney function were significantly different from cases with normal kidney function (p < 0.001). Conclusions. Surveillance of the health of active farm workers and improvement of working conditions, such as sun protection, adequate hydration, and sufficient breaks, are recommended. The significant differences in cystatin C levels between cases with abnormal and reduced kidney function and those with normal kidney function suggest that cystatin C could be a useful measure for early detection of renal disease. |
format |
Article in Journal/Newspaper |
author |
Gerardo Arroyo Gabriella Soto Sofía García Jorge Pérez-Folgar Paola Bailón Brenda Acabal Anita Cocón Mario Díaz-Moscoso Federico Nave |
author_facet |
Gerardo Arroyo Gabriella Soto Sofía García Jorge Pérez-Folgar Paola Bailón Brenda Acabal Anita Cocón Mario Díaz-Moscoso Federico Nave |
author_sort |
Gerardo Arroyo |
title |
Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala |
title_short |
Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala |
title_full |
Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala |
title_fullStr |
Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala |
title_full_unstemmed |
Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala |
title_sort |
prevalence of kidney disease of unknown etiology in agricultural workers, guatemala |
publisher |
Pan American Health Organization |
publishDate |
2023 |
url |
https://doi.org/10.26633/RPSP.2023.84 https://doaj.org/article/3458207f7cae4328a9df076e76bd2f2c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 47, Iss 84, Pp 1-9 (2023) |
op_relation |
https://iris.paho.org/handle/10665.2/57548 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2023.84 https://doaj.org/article/3458207f7cae4328a9df076e76bd2f2c |
op_doi |
https://doi.org/10.26633/RPSP.2023.84 |
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Revista Panamericana de Salud Pública |
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47 |
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